Inactivation of the transcription factor STAT-4 prevents inflammation-driven fibrosis in animal models of systemic sclerosis

Animal models of systemic sclerosis: Prospects and limitations

(2010) Christian Beyer et al.   ARTHRITIS AND RHEUMATISM

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

(2010) Timothy R D J Radstake et al.   NATURE GENETICS

Association of STAT4 polymorphism with systemic sclerosis in a Japanese population

(2009) N Tsuchiya et al.   ANNALS OF THE RHEUMATIC DISEASES

Polymorphisms inTBX21andSTAT4increase the risk of systemic sclerosis: Evidence of possible gene–gene interaction and alterations in Th1/Th2 cytokines

(2009) Pravitt Gourh et al.   ARTHRITIS AND RHEUMATISM

STAT4is a genetic risk factor for systemic sclerosis having additive effects withIRF5on disease susceptibility and related pulmonary fibrosis

(2009) P. Dieudé et al.   ARTHRITIS AND RHEUMATISM

The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis

(2009) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis

(2009) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM

Association between theIRF5rs2004640 functional polymorphism and systemic sclerosis: A new perspective for pulmonary fibrosis

(2009) P. Dieudé et al.   ARTHRITIS AND RHEUMATISM

BANK1is a genetic risk factor for diffuse cutaneous systemic sclerosis and has additive effects withIRF5andSTAT4

(2009) P. Dieudé et al.   ARTHRITIS AND RHEUMATISM

The transcription factor Fra-2 regulates the production of extracellular matrix in systemic sclerosis

(2009) Nicole Reich et al.   ARTHRITIS AND RHEUMATISM

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic background of systemic sclerosis: autoimmune genes take centre stage

(2009) Y. Allanore et al.   RHEUMATOLOGY

STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk

(2008) A-K Abelson et al.   ANNALS OF THE RHEUMATIC DISEASES

ThePTPN22620W allele confers susceptibility to systemic sclerosis: Findings of a large case–control study of European Caucasians and a meta‐analysis

(2008) P. Dieudé et al.   ARTHRITIS AND RHEUMATISM

Association of the STAT4 gene with increased susceptibility for some immune-mediated diseases

(2008) A. Martínez et al.   ARTHRITIS AND RHEUMATISM

The controversial role of tumor necrosis factor α in fibrotic diseases

(2008) Jörg H. W. Distler et al.   ARTHRITIS AND RHEUMATISM

Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis

(2008) Catherine Skhirtladze et al.   ARTHRITIS AND RHEUMATISM

Dual inhibition of c-abl and PDGF receptor signaling by dasatinib and nilotinib for the treatment of dermal fibrosis

(2008) Alfiya Akhmetshina et al.   FASEB JOURNAL

Variant form of STAT4 is associated with primary Sjögren's syndrome

(2008) B D Korman et al.   GENES AND IMMUNITY

STAT4: A risk factor for type 1 diabetes?

(2008) Maria I. Zervou et al.   HUMAN IMMUNOLOGY

The Immunobiology of Systemic Sclerosis

(2008) Y. Stephanie Gu et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM