Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21

Genetically determined Amerindian ancestry correlates with increased frequency of risk alleles for systemic lupus erythematosus

(2010) Elena Sanchez et al.   ARTHRITIS AND RHEUMATISM

Confirmation of an association between rs6822844 at theIl2-Il21region and multiple autoimmune diseases: Evidence of a general susceptibility locus

(2010) Amit K. Maiti et al.   ARTHRITIS AND RHEUMATISM

Novel Association of the Interleukin 2–Interleukin 21 Region With Inflammatory Bowel Disease

(2009) Ana Márquez et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis With IL23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease

(2009) Jürgen Glas et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

A polymorphism withinIL21Rconfers risk for systemic lupus erythematosus

(2009) Ryan Webb et al.   ARTHRITIS AND RHEUMATISM

Recent insights into the genetic basis of systemic lupus erythematosus

(2009) K L Moser et al.   GENES AND IMMUNITY

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis

(2009) E A M Festen et al.   GUT

Follicular helper T cells are required for systemic autoimmunity

(2009) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Review of recent genome-wide association scans in lupus

(2009) R. R. Graham et al.   JOURNAL OF INTERNAL MEDICINE

Th17 cells in rheumatoid arthritis and systemic lupus erythematosus

(2009) A. B. Pernis   JOURNAL OF INTERNAL MEDICINE

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

(2009) H. M. McGuire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A critical role for IL-21 receptor signaling in the pathogenesis of systemic lupus erythematosus in BXSB-Yaa mice

(2009) J. A. Bubier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Interleukin 21 as a target of intervention in autoimmune disease

(2008) R Ettinger et al.   ANNALS OF THE RHEUMATIC DISEASES

Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America

(2008) Roman Kosoy et al.   HUMAN MUTATION

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages

(2008) Roza I. Nurieva et al.   IMMUNITY

Development and characterization of IL-21–producing CD4+T cells

(2008) Akira Suto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE

A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

(2008) Ying Liu et al.   PLoS Genetics