Factor XI Regulates Pathological Thrombus Formation on Acutely Ruptured Atherosclerotic Plaques

Antithrombotic Effect of Antisense Factor XI Oligonucleotide Treatment in Primates

(2013) Jeffrey R. Crosby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanisms of Acute Coronary Syndromes and Their Implications for Therapy

(2013) Peter Libby   NEW ENGLAND JOURNAL OF MEDICINE

Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner

(2013) Julian I. Borissoff et al.   PLoS One

Anticoagulation beyond direct thrombin and factor Xa inhibitors: indications for targeting the intrinsic pathway?

(2013) Maurits van Montfoort et al.   THROMBOSIS AND HAEMOSTASIS

Two novel inhibitory anti-human factor XI antibodies prevent cessation of blood flow in a murine venous thrombosis model

(2013) Maurits L. van Montfoort et al.   THROMBOSIS AND HAEMOSTASIS

Inhibition of factor XI activation attenuates inflammation and coagulopathy while improving the survival of mouse polymicrobial sepsis

(2012) E. I. Tucker et al.   BLOOD

Executive Summary

(2012) Gordon H. Guyatt et al.   CHEST

Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo

(2012) Marie-Luise von Brühl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes

(2011) Asako Itakura et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The procoagulant and proinflammatory plasma contact system

(2011) Thomas Renné   Seminars in Immunopathology

A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo

(2010) Q. Cheng et al.   BLOOD

Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk

(2010) H. Zhang et al.   BLOOD

Coagulation factor XI as a novel target for antithrombotic treatment

(2010) E. C. LÖWENBERG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Stabilizing Role of Platelet P2Y12 Receptors in Shear-Dependent Thrombus Formation on Ruptured Plaques

(2010) Reyhan Nergiz-Unal et al.   PLoS One

Patients with severe factor XI deficiency have a reduced incidence of deep-vein thrombosis

(2010) Ophira Salomon et al.   THROMBOSIS AND HAEMOSTASIS

Reduced incidence of ischemic stroke in patients with severe factor XI deficiency

(2008) O. Salomon et al.   BLOOD

Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model

(2008) M. J. E. KUIJPERS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS