The PI3K signaling pathway mediates the biological effects of leptin

Hypothalamic regulation of food intake and clinical therapeutic applications

(2010) Katherine Anne Simpson et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

PI3K Signaling in the Ventromedial Hypothalamic Nucleus Is Required for Normal Energy Homeostasis

(2010) Yong Xu et al.   Cell Metabolism

Both p110α and p110β Isoforms of Phosphatidylinositol 3-OH-Kinase are Required for Insulin Signalling in the Hypothalamus

(2010) A. Tups et al.   JOURNAL OF NEUROENDOCRINOLOGY

The emerging mechanisms of isoform-specific PI3K signalling

(2010) Bart Vanhaesebroeck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From observation to experimentation: leptin action in the mediobasal hypothalamus

(2009) Kevin W Williams et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Epidemiological and molecular mechanisms aspects linking obesity and cancer

(2009) Felipe Osório-Costa et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons

(2009) Hind Al-Qassab et al.   Cell Metabolism

Should individual PI3 kinase isoforms be targeted in cancer?

(2009) Shidong Jia et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphatidyl Inositol 3-Kinase Signaling in Hypothalamic Proopiomelanocortin Neurons Contributes to the Regulation of Glucose Homeostasis

(2009) Jennifer W. Hill et al.   ENDOCRINOLOGY

Leptin targets in the mouse brain

(2009) Michael M. Scott et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The Ventral Premammillary Nucleus Links Fasting-Induced Changes in Leptin Levels and Coordinated Luteinizing Hormone Secretion

(2009) J. Donato et al.   JOURNAL OF NEUROSCIENCE

Central leptin action improves skeletal muscle AKT, AMPK, and PGC1α activation by hypothalamic PI3K-dependent mechanism

(2009) Erika A.F.R. Roman et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Obesity, the PI3K/Akt signal pathway and colon cancer

(2009) X-F. Huang et al.   Obesity Reviews

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice

(2008) Jennifer W. Hill et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphoinositide 3-Kinase p110  Activity: Key Role in Metabolism and Mammary Gland Cancer but Not Development

(2008) E. Ciraolo et al.   Science Signaling