Structural and Functional Overview of the Lectin Complement Pathway: Its Molecular Basis and Physiological Implication

Mannose-Binding Lectin (MBL)-Associated Serine Protease (MASP)-1 Contributes to Activation of the Lectin Complement Pathway

(2014) Minoru Takahashi et al.   JOURNAL OF IMMUNOLOGY

Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2

(2012) Dávid Héja et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Studies of the Pattern Recognition Molecule H-ficolin

(2012) Rikke M. Zacho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse Ficolin B Has an Ability to Form Complexes with Mannose-Binding Lectin-Associated Serine Proteases and Activate Complement through the Lectin Pathway

(2012) Yuichi Endo et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Human L-Ficolin (Ficolin-2) and Its Clinical Significance

(2012) David C. Kilpatrick et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Mice Deficient in Ficolin, a Lectin Complement Pathway Recognition Molecule, Are Susceptible to Streptococcus pneumoniae Infection

(2012) Y. Endo et al.   JOURNAL OF IMMUNOLOGY

Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function

(2012) S. E. Degn et al.   JOURNAL OF IMMUNOLOGY

Effects of MASP-1 of the Complement System on Activation of Coagulation Factors and Plasma Clot Formation

(2012) Katharina Hess et al.   PLoS One

The Interaction Pattern of Murine Serum Ficolin-A with Microorganisms

(2012) Tina Hummelshøj et al.   PLoS One

Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2

(2012) D. Heja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

(2012) Youssif M. Ali et al.   PLoS Pathogens

New functional ligands for ficolin-3 among lipopolysaccharides of Hafnia alvei

(2011) Anna Swierzko et al.   GLYCOBIOLOGY

Absence of the lectin activation pathway of complement does not increase susceptibility to Pseudomonas aeruginosa infections

(2011) Hany Ibrahim Kenawy et al.   IMMUNOBIOLOGY

The role of ficolins in the lectin pathway of innate immunity

(2011) Yuichi Endo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Near-planar Solution Structures of Mannose-binding Lectin Oligomers Provide Insight on Activation of Lectin Pathway of Complement

(2011) Ami Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Mannose-Binding Lectin-Associated Serine Protease-3 in Activation of the Alternative Complement Pathway

(2011) D. Iwaki et al.   JOURNAL OF IMMUNOLOGY

M-Ficolin Interacts with the Long Pentraxin PTX3: A Novel Case of Cross-Talk between Soluble Pattern-Recognition Molecules

(2011) E. Gout et al.   JOURNAL OF IMMUNOLOGY

Mannose-Binding Lectin-Associated Serine Protease-1 Is a Significant Contributor to Coagulation in a Murine Model of Occlusive Thrombosis

(2011) L. R. La Bonte et al.   JOURNAL OF IMMUNOLOGY

Characterization of the complex between mannose-binding lectin trimer and mannose-binding lectin-associated serine proteases

(2011) Koichiro Tateishi et al.   MICROBIOLOGY AND IMMUNOLOGY

Activation of the alternative complement pathway by mannose-binding lectin via a C2-bypass pathway

(2011) Koichiro Tateishi et al.   MICROBIOLOGY AND IMMUNOLOGY

Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome

(2011) Caroline Rooryck et al.   NATURE GENETICS

Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

(2011) W. J. Schwaeble et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The lectin pathway of complement activation contributes to protection from West Nile virus infection

(2011) Anja Fuchs et al.   VIROLOGY

Carbohydrate recognition and complement activation by rat ficolin-B

(2010) Umakhanth Venkatraman Girija et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Congenital H-ficolin deficiency in premature infants with severe necrotising enterocolitis

(2010) L. J. Schlapbach et al.   GUT

Mannose-binding lectin and its associated proteases (MASPs) mediate coagulation and its deficiency is a risk factor in developing complications from infection, including disseminated intravascular coagulation

(2010) Kazue Takahashi et al.   IMMUNOBIOLOGY

A Novel Mannose-binding Lectin/Ficolin-associated Protein Is Highly Expressed in Heart and Skeletal Muscle Tissues and Inhibits Complement Activation

(2010) Mikkel-Ole Skjoedt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential Role of Complement Mannose-Binding Lectin-Associated Serine Proteases-1/3 in the Murine Collagen Antibody-Induced Model of Inflammatory Arthritis

(2010) N. K. Banda et al.   JOURNAL OF IMMUNOLOGY

Collectin 11 (CL-11, CL-K1) Is a MASP-1/3-Associated Plasma Collectin with Microbial-Binding Activity

(2010) S. Hansen et al.   JOURNAL OF IMMUNOLOGY

Tethering of Ficolin-1 to cell surfaces through recognition of sialic acid by the fibrinogen-like domain

(2010) Christian Honoré et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Functional Analysis of Ficolin-3 Mediated Complement Activation

(2010) Estrid Hein et al.   PLoS One

Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot

(2009) Krishana C. Gulla et al.   IMMUNOLOGY

Synergy between Ficolin-2 and Pentraxin 3 Boosts Innate Immune Recognition and Complement Deposition

(2009) Ying Jie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential role of Mannose-binding lectin-associated serine protease-1 in activation of the complement factor D

(2009) Minoru Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A novel measurement method for activation of the lectin complement pathway via both mannose-binding lectin (MBL) and L-ficolin

(2009) Hiroyuki Inoshita et al.   JOURNAL OF IMMUNOLOGICAL METHODS

MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation

(2009) S. E. Degn et al.   JOURNAL OF IMMUNOLOGY

Complement Protease MASP-1 Activates Human Endothelial Cells: PAR4 Activation Is a Link between Complement and Endothelial Function

(2009) M. Megyeri et al.   JOURNAL OF IMMUNOLOGY

Characteristics and Biological Variations of M-Ficolin, a Pattern Recognition Molecule, in Plasma

(2009) Thomas Wittenborn et al.   Journal of Innate Immunity

The Genetics of Ficolins

(2009) Peter Garred et al.   Journal of Innate Immunity

Ficolins: Complement-Activating Lectins Involved in Innate Immunity

(2009) Misao Matsushita   Journal of Innate Immunity

Interactions of Ficolin and Mannose-Binding Lectin with Fibrinogen/Fibrin Augment the Lectin Complement Pathway

(2009) Yuichi Endo et al.   Journal of Innate Immunity

Immunodeficiency Associated withFCN3Mutation and Ficolin-3 Deficiency

(2009) Lea Munthe-Fog et al.   NEW ENGLAND JOURNAL OF MEDICINE

Local Inflammation Induces Complement Crosstalk Which Amplifies the Antimicrobial Response

(2009) Jing Zhang et al.   PLoS Pathogens

The action of MBL-associated serine protease 1 (MASP1) on factor XIII and fibrinogen

(2008) Anders Krarup et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Stable bronchiectasis is associated with low serum L-ficolin concentrations

(2008) David Chalmers Kilpatrick et al.   Clinical Respiratory Journal

Recognition of acetylated oligosaccharides by human L-ficolin

(2008) Anders Krarup et al.   IMMUNOLOGY LETTERS

Crystal Structure of the CUB1-EGF-CUB2Domain of Human MASP-1/3 and Identification of Its Interaction Sites with Mannan-binding Lectin and Ficolins

(2008) Florence Teillet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma

(2008) Christian Honoré et al.   MOLECULAR IMMUNOLOGY