期刊
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
卷 58, 期 6, 页码 407-415出版社
SPRINGER BASEL AG
DOI: 10.1007/s00005-010-0095-9
关键词
Iron; Metabolism; Macrophage; Inflammation; Lymphocyte
类别
资金
- National Institutes of Health [R56 AI089700]
- Broad Medical Research Program [IBD-0253]
- Crohn's and Colitis Foundation of America
The influence of iron on immune function has been long appreciated. However, the molecular basis for this interaction is less well understood. Recently, there have been several important advances that have shed light on the mechanisms that regulate mammalian iron metabolism. The new insights provide a conceptual framework for understanding and manipulating the cross-talk between iron homeostasis and the immune system. This article will review what is currently known about how disturbances of iron metabolism can affect immunity and how activation of the immune system can lead to alterations in iron balance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据