Article
Gastroenterology & Hepatology
Laurence Daoust, Beatrice S-Y Choi, Sebastien Lacroix, Vanessa Rodrigues Vilela, Thibault Vincent Varin, Stephanie Dudonne, Genevieve Pilon, Denis Roy, Emile Levy, Yves Desjardins, Benoit Chassaing, Andre Marette
Summary: The study compared the impact of prenatal and postnatal environment on maternal gut microbiota and metabolic outcomes in offspring. It was found that the postnatal environment had negative effects on female offspring, leading to adiposity and glucose metabolism issues.
Review
Neurosciences
Claudia Lugo Candelas, Ardesheer Talati, Caila Glickman, Mariely Hernandez, Pamela Scorza, Catherine Monk, Ai Kubo, Chiaying Wei, Andre Sourander, Cristiane S. Duarte
Summary: Studies on prenatal interventions for reducing the risk of psychiatric disorders in offspring have provided mixed and limited evidence. Most research has focused on reducing prenatal depression and anxiety, with some positive effects observed. However, there is a lack of studies on offspring mental health and neurodevelopmental outcomes. More randomized controlled trials focusing on these outcomes are urgently needed.
BIOLOGICAL PSYCHIATRY
(2023)
Review
Psychiatry
Lin Feng Hong, Tze-Ern Chua, Ying Chia Ch'ng, Kate Chui, Helen Yu Chen
Summary: The paper evaluates the outcomes of the Postnatal Depression Intervention Program at KK Hospital in Singapore, focusing on changes in depressive symptoms and overall functioning. The study finds statistically significant changes in these areas. Additionally, the paper describes the demographic characteristics of the 10-year cohort involved in the program.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Article
Medicine, General & Internal
Chaoyu Liu, Eivind Ystrom, Tom A. Mcadams
Summary: The results of this large prospective cohort study suggest that postnatal SSRI treatment was associated with a reduced risk of postnatal depression-associated maternal mental health problems and child externalizing behaviors across early childhood years.
Article
Psychiatry
Fairuz Nazri Abd Rahman, Yun Yaw Wong, Ahmad Qabil Khalib
Summary: Postnatal depression is a significant illness that affects maternal and family health. The rate of postnatal depression is believed to be higher among mental health clients compared to the general community. Children of mental health clients are more likely to have psychological issues. This study explores the prevalence of postnatal depression among mental health clients and its impact on their children's psychological health.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Developmental
Iryna Culpin, Gemma Hammerton, Alan Stein, Marc H. Bornstein, Henning Tiemeier, Tim Cadman, Eivor Fredriksen, Jonathan Evans, Tina Miller, Esther Dermott, Jon Heron, Hannah M. Sallis, Rebecca M. Pearson
Summary: The present study suggests that the adverse effects of maternal postnatal depression on child development cannot be explained by various aspects of paternal involvement. Only father-child conflict has been identified as a risk factor for adverse child development and as a mediator in the association between maternal postnatal depression and child development. If found causal, interventions that reduce father-child conflict may improve developmental outcomes of children of mothers with postnatal depression.
DEVELOPMENTAL PSYCHOLOGY
(2023)
Review
Clinical Neurology
Shaun Sweeney, Charlotte Wilson
Summary: Parental anxiety has an impact on their child's development, with the association being stronger in childhood and adolescence. The influence of both mothers and fathers has been found to negatively affect the functioning of offspring. However, the impact of maternal anxiety may be more significant in adolescence.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Neurosciences
Roza M. Vlasova, Ana-Maria Iosif, Amy M. Ryan, Lucy H. Funk, Takeshi Murai, Shuai Chen, Tyler A. Lesh, Douglas J. Rowland, Jeffrey Bennett, Casey E. Hogrefe, Richard J. Maddock, Michael J. Gandal, Daniel H. Geschwind, Cynthia M. Schumann, Judy Van de Water, A. Kimberley McAllister, Cameron S. Carter, Martin A. Styner, David G. Amaral, Melissa D. Bauman
Summary: This study evaluated the neurodevelopment of male rhesus monkeys born to dams treated with maternal immune activation (MIA), finding subtle changes in cognitive development and deviations from species-typical brain growth trajectories in MIA-treated animals. Longitudinal MRI revealed significant gray matter volume reductions in the prefrontal and frontal cortices of MIA-treated offspring at 6 months, along with smaller frontal white matter volumes at later time points. These findings provide evidence of early postnatal changes in brain development in MIA-exposed nonhuman primates, establishing a relevant model system to explore the neurodevelopmental trajectory associated with prenatal immune challenge.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Nutrition & Dietetics
Kacper Witek, Karolina Wydra, Agata Suder, Malgorzata Filip
Summary: Anxiety and depression are common mental disorders affecting people worldwide. Recent studies have shown that a maternal high-sugar diet can increase the risk of mood disorders in offspring. This study evaluated the effects of maternal monosaccharide consumption during pregnancy and lactation on cognitive and emotional disturbances in adolescent and young adult rats. The results suggest that maternal monosaccharide consumption is an important factor affecting the emotional status of offspring.
FRONTIERS IN NUTRITION
(2023)
Article
Psychology, Developmental
Sara R. Jaffee, Judith L. Sligo, Helena M. McAnally, Aroha E. Bolton, Joanne M. Baxter, Robert J. Hancox
Summary: Recurrent depression in both fathers and mothers increases offspring risk for depression, particularly when it starts in childhood or adolescence, but a single lifetime episode does not. The intergenerational effect did not vary as a function of parent or offspring sex. Adolescent depression prevalence was 2.5 times higher in the offspring than in the parents' generation at age 15.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2021)
Article
Psychology, Developmental
Benjamin W. Nelson, Lisa Sheeber, Jennifer Pfeifer, Nicholas B. Allen
Summary: The study found that maternal depression is associated with increased allostatic load in depressed women and their adolescent children, possibly increasing the risk for early onset of psychiatric conditions and disease in these offspring. The research also indicated differences in mental and physical health risk profiles between depressed mothers and their adolescent offspring, suggesting higher allostatic load in the affected individuals. Further investigation is needed to understand why certain biological systems are more impacted than others and to develop preventative programs for the adolescent offspring of depressed mothers.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2021)
Article
Endocrinology & Metabolism
Emily Lipner, Shannon K. Murphy, Elizabeth C. Breen, Barbara A. Cohn, Nickilou Y. Krigbaum, Piera M. Cirillo, Lauren B. Alloy, Lauren M. Ellman
Summary: Prenatal infection and stress may influence offspring depression outcomes, especially during mid-gestation. Higher levels of maternal cortisol may contribute to this effect.
PSYCHONEUROENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Lachlan T. Strike, Narelle K. Hansell, Kai-Hsiang Chuang, Jessica L. Miller, Greig I. de Zubicaray, Paul M. Thompson, Katie L. McMahon, Margaret J. Wright
Summary: The QTAB dataset includes multimodal neuroimaging, cognitive, and mental health data of adolescent twins. It provides a detailed methodology and technical validation for data usage. The project aims to promote health-related research in adolescence.
Article
Cell Biology
Yuri Karen Sinzato, Veronyca Goncalves Paula, Franciane Quintanilha Gallego, Rafaianne Q. Moraes-Souza, Jose Eduardo Corrente, Gustavo Tadeu Volpato, Debora Cristina Damasceno
Summary: Maternal diabetes and high-fat diet have similar adverse effects on the health of F1 and F2 generations, including infertility, decreased insulin sensitivity, and fetal growth restriction. The combination of both factors also results in increased lipoperoxidation, decreased glucose tolerance, and increased fetal leptin levels.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Yujung Michelle Lee, Andre Mu, Martina Wallace, Jivani M. Gengatharan, Annalee J. Furst, Lars Bode, Christian M. Metallo, Janelle S. Ayres
Summary: Maternal behavior is crucial for the optimal development and growth of offspring, while the intestinal microbiota plays a key role in regulating growth and development. Certain strains of Escherichia coli were found to be pathogenic to the maternal-offspring system, leading to growth stunting by interfering with maternal behavior rather than directly affecting the infants. This study provides new insights into how microbiota regulates postnatal growth and highlights an additional variable to consider when studying the regulation of maternal behavior.
Article
Psychiatry
Heather A. O'Mahen, Paul G. Ramchandani, Dorothy X. King, Leonie Lee-Carbon, Esther L. Wilkinson, Chloe Thompson-Booth, Jennifer Ericksen, Jeannette Milgrom, Jacqueline Dunkley-Bent, Sarah L. Halligan, Pasco Fearon
Summary: This study investigated the acceptability and feasibility of a new brief intervention for maternal prenatal anxiety in maternity services. The results showed that the intervention was acceptable to pregnant individuals and their partners, and led to a reduction in anxiety levels.
Editorial Material
Health Policy & Services
Lauren Stewart, Bonnie B. McConnell, Buba Darboe, Vivette Glover, Hajara B. Huma, Katie Rose M. Sanfilippo, Ian Cross, Hassoum Ceesay, Paul Ramchandani, Victoria Cornelius
Summary: Arts in Health initiatives and interventions have mainly focused on WEIRD contexts, ignoring the rich cultural traditions worldwide. However, utilizing these traditions as a starting point can enhance the co-creation, cultural embeddedness, and partnership building in global health research, as demonstrated by the CHIME project in The Gambia.
HEALTH PROMOTION INTERNATIONAL
(2022)
Review
Psychology, Educational
Kayleigh Skene, Christine M. O'Farrelly, Elizabeth M. Byrne, Natalie Kirby, Eloise C. Stevens, Paul G. Ramchandani
Summary: This systematic review and meta-analysis compared the effects of guided play, direct instruction, and free play on children's learning and development. The findings showed that guided play had a positive impact on early maths skills, shape knowledge, and task switching, outperforming direct instruction. It also had a greater effect on spatial vocabulary compared to free play. However, there was heterogeneity in the conceptualization and implementation of guided play across studies.
Review
Obstetrics & Gynecology
Rosie Attard, Jane Iles, Rose-Marie Satherley
Summary: Poor mental health in the postnatal period is common among parents and has a high cost to society. Accessing therapeutic support during this time is complicated by parenting responsibilities. E-Health interventions offer a potential solution by providing convenient and flexible support. However, further research is needed to understand the acceptability of these interventions for parents.
BMC PREGNANCY AND CHILDBIRTH
(2022)
Article
Psychology, Clinical
Kirsten Barnicot, Morgan Welsh, Sarah Kalwarowsky, Eloise Stevens, Jane Iles, Jennie Parker, Maddalena Miele, Tara Lawn, Laura O'Hanlon, Sushma Sundaresh, Ola Ajala, Paul Bassett, Christina Jones, Paul Ramchandani, Mike Crawford
Summary: This study evaluated the feasibility and acceptability of a video feedback intervention for positive parenting adapted for perinatal mental health, showing high intervention uptake and completion rates. While some positive effects were seen in the intervention group, no clear intervention effects were observed in other areas.
BRITISH JOURNAL OF CLINICAL PSYCHOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Stephen Bayley, Darge Wole Meshesha, Pauline Rose, Tassew Woldehanna, Louise Yorke, Paul Ramchandani
Summary: This paper presents the findings of longitudinal research in Ethiopia on the impact of COVID-19 school closures on children's holistic learning. The study compares dropout rates and learning outcomes before and after the closures, using data from over 2,000 primary school children. The findings highlight the risk of widening educational inequality based on gender, age, wealth, and location, as well as a decline in social skills and the positive relationship between social skills and numeracy. The study recommends the promotion of holistic learning in education systems, particularly in the aftermath of the pandemic.
LONGITUDINAL AND LIFE COURSE STUDIES
(2023)
Article
Psychology, Clinical
Kirsten Barnicot, Jennie Parker, Sarah Kalwarowsky, Eloise Stevens, Jane Iles, Paul Ramchandani, Mike Crawford
Summary: This study explored the experiences of mothers and clinicians in a video feedback intervention adapted for perinatal 'personality disorder' (VIPP-PMH) and the acceptability of a randomised controlled trial (RCT) testing its effectiveness. In-depth qualitative interviews were conducted with participants from a two-phase feasibility study, including mothers experiencing difficulties in managing emotions and relationships and their 6- to 36-month-old children. The findings suggest that a future definitive RCT of the VIPP-PMH intervention in this population is likely to be feasible and acceptable.
PSYCHOLOGY AND PSYCHOTHERAPY-THEORY RESEARCH AND PRACTICE
(2023)
Article
Medicine, Research & Experimental
Camilla Rosan, Kim Alyousefi-van Dijk, Zoe Darwin, Daphne Babalis, Victoria Cornelius, Rachel Phillips, Lani Richards, Hannah Wright, Steve Pilling, Pasco Fearon, Elena Pizzo, Peter Fonagy
Summary: This study plans to conduct a randomized controlled trial to test the effectiveness of Circle of Security-Parenting (COS-P) in improving the mental health symptoms of birthing parents accessing NHS perinatal mental health services. The trial also aims to explore whether the intervention can improve parenting sensitivity, emotion regulation skills, attachment security, and infant development. This research is significant for birthing parents with perinatal mental health difficulties.
Article
Psychology, Developmental
Emily J. Goodacre, Elian Fink, Paul Ramchandani, Jenny L. Gibson
Summary: Effective reciprocal communication is crucial for social relationships and peer social play is an important context for communication skill development. The study explores how speakers coordinate ideas in peer social play to build a shared play experience. The results show that connectedness is influenced by dyadic effects rather than individual socio-cognitive measures.
BRITISH JOURNAL OF DEVELOPMENTAL PSYCHOLOGY
(2023)
Article
Social Work
Kelsey Graber, Christine O'Farrelly, Paul Ramchandani
Summary: Despite the COVID-19 pandemic and lockdown measures, children's need and engagement in play remained high, highlighting the enduring value of play in their lives.
CHILDREN & SOCIETY
(2023)
Review
Education & Educational Research
Elizabeth M. M. Byrne, Hanne Jensen, Bo Stjerne Thomsen, Paul G. G. Ramchandani
Summary: This scoping review examined the effectiveness of educational physical manipulatives interventions with pre-primary and primary-age children. The findings showed that physical manipulatives have the most promising effects on math learning, as well as positive impacts on spatial, literacy, and science skills. However, caution should be exercised due to methodological shortcomings and inconsistent results.
REVIEW OF EDUCATION
(2023)
Article
Education & Educational Research
Dina D. D. Fajardo-Tovar, Kelsey M. M. Graber, Sabilah Eboo Alwani, Natalie Kirby, Laura Oxley, Sara Baker, Paul Ramchandani
Summary: The COVID-19 pandemic had a significant impact on our daily lives and research projects at the PEDAL Centre. We quickly adapted our projects to ensure continuity and learned important lessons from the experience. This paper uses the 6Cs framework to describe our retrospective learnings from adjusting to the unprecedented circumstances, emphasizing the key role of a 'playful' mindset in overcoming challenges and providing insights for moving forward after the pandemic.
INTERNATIONAL JOURNAL OF PLAY
(2023)
Article
Medicine, General & Internal
Katie Rose M. Sanfilippo, Vivette Glover, Victoria Cornelius, Rita T. Amiel Castro, Bonnie McConnell, Buba Darboe, Hajara B. Huma, Hassoum Ceesay, Paul Ramchandani, Ian Cross, Lauren Stewart
Summary: It is important to detect symptoms of common mental disorders (CMDs) in pregnant women, but cultural differences and scale variations can affect their expression. This study compared Gambian pregnant women's responses to the Edinburgh Postnatal Depression Scale (EPDS) and Self-reporting Questionnaire (SRQ-20), as well as comparing responses to the EPDS between pregnant women in The Gambia and the UK.
Review
Psychology, Developmental
Nicola Hopkins, Jane Iles, Rose-Marie Satherley
Summary: Autistic females present differently from autistic males, leading to difficulties in diagnosis and support. Parenting an autistic daughter is associated with additional stress, but research in this area is limited. Analysis found challenges in diagnosis and differences in lived experience compared to autistic males, but also benefits to parenting a daughter.
REVIEW JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Meeting Abstract
Psychology, Multidisciplinary
Christine O'Farrelly, Ellen Grimas, Beth Barker, Eloise Stevens, Paul Ramchandani
JOURNAL OF REPRODUCTIVE AND INFANT PSYCHOLOGY
(2022)
