PI3K signaling mediates diverse regulation of ATF4 expression for the survival of HK-2 cells exposed to cadmium

Roles of EGFR, PI3K, AKT, and mTOR in Heavy Metal-Induced Cancer

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Transforming Growth Factor β Suppresses Osteoblast Differentiation via the Vimentin Activating Transcription Factor 4 (ATF4) Axis

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Upregulation of amino acid transporter expression induced by l-leucine availability in L6 myotubes is associated with ATF4 signaling through mTORC1-dependent mechanism

(2012) Jun-qiu Luo et al.   NUTRITION

Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling

(2012) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of salubrinal on cadmium-induced apoptosis in HK-2 human renal proximal tubular cells

(2011) Yuta Komoike et al.   ARCHIVES OF TOXICOLOGY

Regulation and function of the RSK family of protein kinases

(2011) Yves Romeo et al.   BIOCHEMICAL JOURNAL

Akt signalling in health and disease

(2011) Ingeborg Hers et al.   CELLULAR SIGNALLING

Cadmium Increases HIF-1 and VEGF Expression through ROS, ERK, and AKT Signaling Pathways and Induces Malignant Transformation of Human Bronchial Epithelial Cells

(2011) Yi Jing et al.   TOXICOLOGICAL SCIENCES

Involvement of both intrinsic and extrinsic pathways in hepatoprotection of arjunolic acid against cadmium induced acute damage in vitro

(2011) Sankhadeep Pal et al.   TOXICOLOGY

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Endoplasmic reticulum stress as a progression factor for kidney injury

(2010) Reiko Inagi   CURRENT OPINION IN PHARMACOLOGY

TGFβ enforces activation of eukaryotic elongation factor-2 (eEF2) via inactivation of eEF2 kinase by p90 ribosomal S6 kinase (p90Rsk) to induce mesangial cell hypertrophy

(2010) Falguni Das et al.   FEBS LETTERS

Insulin modulates induction of glucose-regulated protein 78 during endoplasmic reticulum stress via augmentation of ATF4 expression in human neuroblastoma cells

(2010) Kiyoshi Inageda   FEBS LETTERS

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

(2010) Long Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony

(2010) Kathryn G. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activating transcription factor 4 regulates osteoclast differentiation in mice

(2010) Huiling Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

Pleiotropic effects of cadmium in mesangial cells

(2009) Weiqun Xiao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The RSK family of kinases: emerging roles in cellular signalling

(2008) Rana Anjum et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY