Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?
出版年份 2011 全文链接
标题
Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?
作者
关键词
-
出版物
ARCHIVES OF TOXICOLOGY
Volume 85, Issue 11, Pages 1361-1372
出版商
Springer Nature
发表日期
2011-10-18
DOI
10.1007/s00204-011-0767-1
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Re-evaluation of animal numbers and costs for in vivo tests to accomplish REACH legislation requirements for chemicals - a report by the Transatlantic Think Tank for Toxicology (t4)
- (2016) Costanza Rovida ALTEX-Alternatives to Animal Experimentation
- New Directions in Toxicity Testing
- (2011) Daniel Krewski et al. Annual Review of Public Health
- Present state and future perspectives of using pluripotent stem cells in toxicology research
- (2011) Anna M. Wobus et al. ARCHIVES OF TOXICOLOGY
- Isolation of Epiblast Stem Cells from Preimplantation Mouse Embryos
- (2011) Fadi J. Najm et al. Cell Stem Cell
- Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment
- (2011) Richard S. Judson et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Chemical toxicity testing in vitro using cytochrome P450–expressing cell lines, such as human CYP1B1
- (2011) Robert Landsiedel et al. Nature Protocols
- The validated embryonic stem cell test to predict embryotoxicity in vitro
- (2011) Andrea E M Seiler et al. Nature Protocols
- Pluripotent Human Stem Cells
- (2010) Blaine W. Phillips et al. BIODRUGS
- Predicting developmental toxicity through toxicogenomics
- (2010) George P. Daston et al. BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS
- Toward a Comprehensive Molecular Design Framework for Reduced Hazard
- (2010) Adelina M. Voutchkova et al. CHEMICAL REVIEWS
- Commentary on ‘‘Toxicity Testing in the 21st Century: A vision and a Strategy’’: Stem Cells and Cell-Cell Communication as Fundamental Targets in Assessing the Potential Toxicity of Chemicals
- (2010) James E Trosko HUMAN & EXPERIMENTAL TOXICOLOGY
- Lessons Learned from Alternative Methods and their Validation for a New Toxicology in the 21st Century
- (2010) Thomas Hartung JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
- In vitro-Ishikawa cell test for assessing tissue-specific chemical effects on human endometrium
- (2010) W.R. Schaefer et al. REPRODUCTIVE TOXICOLOGY
- Transferability and inter-laboratory variability assessment of the in vitro bovine oocyte maturation (IVM) test within ReProTect
- (2010) Alberto M. Luciano et al. REPRODUCTIVE TOXICOLOGY
- Assessing developmental osteotoxicity of chlorides in the embryonic stem cell test
- (2010) Nicole I. zur Nieden et al. REPRODUCTIVE TOXICOLOGY
- The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants
- (2010) Barbara Schenk et al. REPRODUCTIVE TOXICOLOGY
- Reconstituting Organ-Level Lung Functions on a Chip
- (2010) D. Huh et al. SCIENCE
- The Vision of Toxicity Testing in the 21st Century: Moving from Discussion to Action
- (2010) Melvin E. Andersen et al. TOXICOLOGICAL SCIENCES
- Comparing three novel endpoints for developmental osteotoxicity in the embryonic stem cell test
- (2010) Nicole I. zur Nieden et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- The Potential of Embryonic Stem Cells Combined with -omics Technologies as Model Systems for Toxicology
- (2009) J. Winkler et al. CURRENT MEDICINAL CHEMISTRY
- Toxicology for the twenty-first century
- (2009) Thomas Hartung NATURE
- Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells
- (2009) Siqin Bao et al. NATURE
- The evolution of hierarchical gene regulatory networks
- (2009) Douglas H. Erwin et al. NATURE REVIEWS GENETICS
- Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: State of the science
- (2009) Joseph M. Breier et al. NEUROTOXICOLOGY AND TERATOLOGY
- ReProGlo: A new stem cell-based reporter assay aimed to predict embryotoxic potential of drugs and chemicals
- (2009) Frederik Uibel et al. REPRODUCTIVE TOXICOLOGY
- Endless Possibilities: Stem Cells and the Vision for Toxicology Testing in the 21st Century
- (2009) Robert E. Chapin et al. TOXICOLOGICAL SCIENCES
- Embryonic Stem Cell Test Remastered: Comparison between the Validated EST and the New Molecular FACS-EST for Assessing Developmental Toxicity In Vitro
- (2009) Roland Buesen et al. TOXICOLOGICAL SCIENCES
- Challenges of using pluripotent stem cells for safety assessments of substances
- (2009) Kinga Vojnits et al. TOXICOLOGY
- Factors to consider in the use of stem cells for pharmaceutic drug development and for chemical safety assessment
- (2009) James Edward Trosko et al. TOXICOLOGY
- High-throughput cellular microarray platforms: applications in drug discovery, toxicology and stem cell research
- (2009) Tiago G. Fernandes et al. TRENDS IN BIOTECHNOLOGY
- Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming
- (2009) Wenlin Li et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Assessment of the Embryonic Stem Cell Test and application and use in the pharmaceutical industry
- (2008) Jennifer A. Paquette et al. BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY
- Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development
- (2008) Charles E. Murry et al. CELL
- Evo-Devo: Variations on Ancestral Themes
- (2008) E.M. De Robertis CELL
- High-Throughput Screening Assay for the Identification of Compounds Regulating Self-Renewal and Differentiation in Human Embryonic Stem Cells
- (2008) Sabrina C. Desbordes et al. Cell Stem Cell
- Mesodermal fate decisions of a stem cell: the Wnt switch
- (2008) L. A. Davis et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Characterization of Diversity in Toxicity Mechanism Using in Vitro Cytotoxicity Assays in Quantitative High Throughput Screening
- (2008) Ruili Huang et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Systems biology and functional genomics approaches for the identification of cellular responses to drug toxicity
- (2008) Alison Hege Harrill et al. Expert Opinion on Drug Metabolism & Toxicology
- Pluripotent stem cell lines
- (2008) J. Yu et al. GENES & DEVELOPMENT
- Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?
- (2008) Giovanna Mazzoleni et al. Genes and Nutrition
- Development of a gene-trap vector with a highly sensitive fluorescent protein reporter system for expression profiling
- (2008) Tetsuya S. Tanaka et al. GENESIS
- Canine embryo-derived stem cells and models for human diseases
- (2008) M. R. Schneider et al. HUMAN MOLECULAR GENETICS
- Tackling the epigenome in the pluripotent stem cells
- (2008) Xiaodong Zhao et al. Journal of Genetics and Genomics
- Marked differences in differentiation propensity among human embryonic stem cell lines
- (2008) Kenji Osafune et al. NATURE BIOTECHNOLOGY
- Relevance of in vitro neurotoxicity testing for regulatory requirements: Challenges to be considered
- (2008) Anna K. Bal-Price et al. NEUROTOXICOLOGY AND TERATOLOGY
- Human developmental neurotoxicity of methylmercury: Impact of variables and risk modifiers
- (2008) Anna F. Castoldi et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- REACH, non-testing approaches and the urgent need for a change in mind set
- (2008) G. Schaafsma et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Transforming Environmental Health Protection
- (2008) Francis S. Collins et al. SCIENCE
- Efficient Differentiation of Hepatocytes from Human Embryonic Stem Cells Exhibiting Markers Recapitulating Liver Development In Vivo
- (2008) David C. Hay et al. STEM CELLS
- Derivation and Characterization of Canine Embryonic Stem Cell Lines with In Vitro and In Vivo Differentiation Potential
- (2008) Andrea K. Vaags et al. STEM CELLS
- In Vitro Differentiation of Embryonic and Adult Stem Cells into Hepatocytes: State of the Art
- (2008) Sarah Snykers et al. STEM CELLS
- Evaluation of the Embryotoxic Potency of Compounds in a Newly Revised High Throughput Embryonic Stem Cell Test
- (2008) Annelieke K. Peters et al. TOXICOLOGICAL SCIENCES
- Toxicity Testing in the 21st Century: Bringing the Vision to Life
- (2008) Melvin E. Andersen et al. TOXICOLOGICAL SCIENCES
- Automated analysis of contractility in the embryonic stem cell test, a novel approach to assess embryotoxicity
- (2008) Annelieke K. Peters et al. TOXICOLOGY IN VITRO
- A microwell array system for stem cell culture
- (2007) Hannes-Christian Moeller et al. BIOMATERIALS
- Microenvironments Engineered by Inkjet Bioprinting Spatially Direct Adult Stem Cells Toward Muscle- and Bone-Like Subpopulations
- (2007) Julie A. Phillippi et al. STEM CELLS
- Derivation, Characterization, and In Vitro Differentiation of Canine Embryonic Stem Cells
- (2007) Brian Hayes et al. STEM CELLS
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started