Article
Food Science & Technology
Alessandro Picelli, Andrea Santamato, Michela Cosma, Alessio Baricich, Carmelo Chisari, Marzia Millevolte, Cristina Del Prete, Ilenia Mazzu, Paolo Girardi, Nicola Smania
Summary: This study aimed to investigate the relationship between the timing of BoNT-A injection and treatment outcomes in PSS patients. The results showed that initiating BoNT-A treatment within 3 months post-stroke can lead to greater reduction in muscle tone at 1 and 3 months follow-up.
Review
Rehabilitation
Hui-Min Xie, Ting-Ting Guo, Xuan Sun, Han-Xiao Ge, Xue-Dan Chen, Ke-Jia Zhao, Li-Ning Zhang
Summary: This study evaluated the effectiveness of botulinum toxin A in the treatment of hemiplegic shoulder pain, finding that BTX-A injection provided greater analgesic effects and increased shoulder abduction and external rotation range of motion compared with steroid or placebo injection.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Medicine, General & Internal
Yuma Kadoya, Nobuhiro Tanaka, Takanori Suzuka, Takayuki Yamanaka, Masato Iwata, Naoki Ozu, Masahiko Kawaguchi
Summary: The decrease in quadriceps strength after anterior quadratus lumborum block (AQLB) has not been studied in depth. This prospective study aimed to investigate the incidence of quadriceps weakness after AQLB. The results showed that 13.3% of patients experienced muscle weakness compared with their preoperative baseline, and 30.0% experienced weakness compared with the non-block side. However, all patients were able to walk within 24 hours after surgery, indicating that the weakness was transient.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Food Science & Technology
Sheng Li
Summary: Stiff knee gait (SKG), characterized by decreased knee flexion during the swing phase, is a common gait disorder following stroke. Knee extensor spasticity is considered the primary cause, and clinical management focuses on reducing this spasticity. However, recent research suggests that SKG can result from mechanical consequences between muscle spasticity, weakness, and ground reactions during walking. Sample cases in this article present various underlying mechanisms, including ankle plantar flexor spasticity, knee extensor spasticity, knee flexor and extensor coactivation, and hip flexor spasticity. Careful clinical assessment is advised to determine the primary cause in each patient, and understanding these different presentations of SKG can aid in selecting appropriate muscles for intervention.
Article
Health Care Sciences & Services
Silvia Faccioli, Silvia Sassi, Daniela Pandarese, Corrado Borghi, Valentina Montemaggiori, Marina Sarzana, Stefano Scarparo, Carla Butera, Valeria Calbi, Alessandro Aiuti, Francesca Fumagalli
Summary: This case report describes the long-term management of a child with late infantile metachromatic leukodystrophy (MLD) who received hematopoietic stem and progenitor cell gene therapy (HSPC-GT). Various interventions, including orthoses, a walker, orthopedic surgery, physiotherapy, and botulinum, were effective in improving gait impairment and muscle imbalance. However, caution is advised when using botulinum due to the risk of inducing overall weakness.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Food Science & Technology
Alessandro Picelli, Mirko Filippetti, Giorgio Sandrini, Cristina Tassorelli, Roberto De Icco, Nicola Smania, Stefano Tamburin
Summary: This systematic review provides a comprehensive overview of the current literature on the protocols of electrical stimulation to enhance the effect of BoNT-A injection in treating spasticity. Data on patient characteristics, electrical stimulation protocols, and outcome measures were collected and critically discussed based on the neurobiology of BoNT-A uptake.
Article
Rehabilitation
Rashid Kazerooni, Ileana Howard, Xiaomeng Li, Monica Verduzco-Gutierrez
Summary: This study aimed to estimate the differences in botulinum toxin type A (BoNT-A) treatment costs per patient for spasticity. The results showed that physicians who used abobotulinumtoxinA and/or incobotulinumtoxinA had significantly lower average costs per patient per year compared to those who used only onabotulinumtoxinA.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Rehabilitation
Paul Winston, Rajiv Reebye, Alessandro Picelli, Romain David, Eve Boissonnault
Summary: The diagnostic nerve block (DNB) for spasticity is the temporary paralysis of a nerve using anesthesia to assess its impact on spastic patterns. This study highlights the potential advantages of using ultrasound (US) guidance, such as rapid target localization and avoidance of intravascular injection, in improving DNB techniques. Further research is needed to investigate the use of US in conjunction with electrical stimulation for spasticity management.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Rehabilitation
Woo-Sub Kim, Hanboram Choi, Jung-Woo Jung, Joon Sik Yoon, Ju Hyong Jeoung
Summary: This study aimed to extract independent features from poststroke gait data and found that temporal asymmetry and variability are important factors in early rehabilitation. These characteristics are independent of each other and can guide the assessment and treatment strategy in poststroke gait rehabilitation.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Rehabilitation
Mirko Filippetti, Rita Di Censo, Valentina Varalta, Alessio Baricich, Andrea Santamato, Nicola Smania, Alessandro Picelli
Summary: This study found a correlation between spastic calf muscles echo intensity and the outcome of tibial nerve motor branches selective block in patients with spastic equinovarus foot. Patients with higher spastic calf muscles echo intensity had a poor response to the nerve block.
JOURNAL OF REHABILITATION MEDICINE
(2022)
Review
Rehabilitation
Emanuela E. Mihai, Marius N. Popescu, Alina N. Iliescu, Mihai Berteanu
Summary: This systematic review evaluates and compares the effectiveness of extracorporeal shock wave therapy (ESWT) with botulinum toxin type A (BoNT-A) in reducing spasticity in children and adults. The review includes five studies and the results indicate that both ESWT and BoNT-A have a beneficial effect on spasticity in post-stroke, multiple sclerosis, and cerebral palsy patients. However, further research and more suitable study protocols are needed to strengthen the evidence.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2022)
Article
Rehabilitation
Ian J. Baguley, Hannah L. Barden, Karen Byth
Summary: The study revealed that hand relaxation deteriorated during repetitive movements in people with spasticity, but the deterioration improved after controlling for inducible muscle overactivity.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Rehabilitation
Kirsten Platho-Elwischger, Michaela Schmoeger, Ulrike Willinger, Carmen Abdel-Aziz, Jennifer Algner, Sandra Pretscherer, Eduard Auff, Gottfried Kranz, Oliver Turnbull, Thomas Sycha
Summary: This study investigated the effects of botulinum toxin injections on higher cognitive functions in patients with blepharospasm or hemifacial spasm. The findings showed that patients who received facial BTX injections performed worse in nonverbal reasoning tasks compared to those who did not receive injections. However, there was no significant difference in verbal reasoning scores between the groups. Further research is needed to determine the causality behind these findings.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Rehabilitation
Allison Miller, Ryan T. Pohlig, Tamara Wright, Hyosub E. Kim, Darcy S. Reisman
Summary: This study identified latent classes of survivors of chronic stroke using a mixture model and found significant differences in walking ability, psychosocial factors, environment, and cognition among these classes. The results indicated that real-world walking activity in survivors of stroke is influenced by multiple factors including walking ability, self-efficacy, cognitive function, and socioeconomic environment.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Review
Rehabilitation
Dario Calafiore, Francesco Negrini, Nicola Tottoli, Francesco Ferraro, Ozden Ozyemisci-Taskiran, Alessandro de Sire
Summary: This study evaluated the efficacy of Robot-assisted gait rehabilitation (RAGT) for gait recovery in subacute stroke survivors, showing its potential role in this field, though further research comparing its effectiveness with conventional physical therapy is still needed in the neurorehabilitation field.
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2022)
Article
Engineering, Biomedical
Rene Fluit, Erik C. Prinsen, Shiqian Wang, Herman van der Kooij
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2020)
Article
Clinical Neurology
Marijn Mulder, Corien Nikamp, Rinske Nijland, Erwin van Wegen, Erik Prinsen, Judith Vloothuis, Jaap Buurke, Gert Kwakkel
Summary: The Armed4Stroke study aims to investigate the effects of a caregiver-mediated exercise program using a blended care approach in addition to usual care, on recovery of mobility in the first 6 months poststroke. The study includes a multicentre, observer-blinded randomized clinical trial with 74 patient-caregiver dyads, assessing self-reported mobility, care transition preparedness, psychological functioning, and other outcomes.
Article
Robotics
Robert Schulte, Erik C. Prinsen, Hermie J. Hermens, Jaap H. Buurke
Summary: The study demonstrates that a feature set based on the features selected by a genetic algorithm outperforms the state-of-the-art set, leading to improved accuracy in lower limb myoelectric control. The selected feature sets were evaluated on the remaining test set and an online benchmark dataset ENABL3S in the experiment.
FRONTIERS IN ROBOTICS AND AI
(2021)
Article
Robotics
Robert V. Schulte, Marijke Zondag, Jaap H. Buurke, Erik C. Prinsen
Summary: Proportional control using surface electromyography enables more intuitive control of a transfemoral prosthesis. This study compared three different modelling frameworks for knee torque estimation and found that the convolutional neural network model performed the best in terms of error rate.
FRONTIERS IN ROBOTICS AND AI
(2022)
Article
Robotics
Jesus de Miguel-Fernandez, Camille Pescatore, Alba Mesa-Garrido, Cindy Rikhof, Erik Prinsen, Josep M. Font-Llagunes, Joan Lobo-Prat
Summary: Recent studies have shown that ankle exoskeletons can improve gait biomechanics and walking performance for post-stroke individuals. This comprehensive experimental analysis and protocol evaluated a wide range of metrics and showed that the ABLE-S exoskeleton significantly corrected foot drop, reduced compensatory movements, and improved gait patterns.
IEEE ROBOTICS AND AUTOMATION LETTERS
(2022)
Article
Chemistry, Analytical
Robert V. Schulte, Erik C. Prinsen, Jaap H. Buurke, Mannes Poel
Summary: This study investigated the development of error rate over one week and compared three adaptation strategies to reduce error rate increase. Among the three tested strategies, entropy based adaptation showed the smallest increase in error rate over time. This suggests that entropy based adaptation is a simple and feasible strategy for lower limb pattern recognition.
Article
Robotics
Anthony Remazeilles, Alfonso Dominguez, Pierre Barralon, Adriana Torres-Pardo, David Pinto, Felix Aller, Katja Mombaur, Roberto Conti, Lorenzo Saccares, Freygardur Thorsteinsson, Erik Prinsen, Alberto Canton, Javier Castilla, Clara B. Sanz-Morere, Jesus Tornero, Diego Torricelli
Summary: This study presents a software methodology for systematic benchmarking of bipedal systems. The methodology focuses on standardizing the scoring process and proposes a simple but efficient approach for preparing scoring algorithms. The study also highlights the use of continuous integration and deployment tools for ensuring replicability of the software and generating executable instances.
FRONTIERS IN ROBOTICS AND AI
(2022)
Review
Engineering, Biomedical
Vera G. M. Kooiman, Eline S. van Staveren, Ruud A. Leijendekkers, Jaap H. Buurke, Nico Verdonschot, Erik C. Prinsen, Vivian Weerdesteyn
Summary: This review examines the characteristics, protocols, aims, and outcome measures used during prosthesis prototype testing on individuals with a transfemoral amputation. The results indicate significant variations in research protocols and outcome measures, highlighting the need for a core set of reported characteristics, testing protocols, and outcome measures to evaluate prosthetic developments.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2023)
Review
Engineering, Biomedical
Jesus de Miguel-Fernandez, Joan Lobo-Prat, Erik Prinsen, Josep M. Font-Llagunes, Laura Marchal-Crespo
Summary: In the past decade, there has been progress in the development of robotic controllers for lower-limb exoskeletons to interact with brain-injured patients. However, the most effective control strategies for motor function recovery are still uncertain. This review provides a framework of current control strategies, analyzes the methodology of clinical validations, and explores the relation between control strategies and clinical outcomes.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2023)
Article
Multidisciplinary Sciences
Robert V. Schulte, Erik C. Prinsen, Leendert Schaake, Robert P. G. Paassen, Marijke Zondag, Eline S. van Staveren, Mannes Poel, Jaap H. Buurke
Summary: This data descriptor introduces the Roessingh Research & Development-MyLeg database for activity prediction (MyPredict), which consists of three data sets. These data sets include measurements from 55 able-bodied subjects, with an average age of 24 ± 2 years, recorded in 85 measurement sessions. The data encompasses various activities such as sitting, standing, walking, stair ascent and descent, ramp ascent and descent, walking on uneven terrain, and walking in simulated confined spaces. The recorded data includes joint angles, sensor accelerations, angular velocity, orientation, virtual marker positions, and sEMG signals. The data presented in this descriptor serve as a valuable resource for research in myoelectric pattern recognition, myoelectric control development, and electromyography in data-driven applications.
Review
Rehabilitation
Anoek M. Geers, Erik C. Prinsen, Dick J. van der Pijl, Arjen Bergsma, Johan S. Rietman, Bart F. J. M. Koopman
Summary: In this study, an overview of wheelchair mounted head supports and associated scientific evidence is provided to identify requirements for the next generation of head support systems. The study emphasizes the need for personalized head support systems that combine changes in sitting and head position with continuous optimal support for severely challenged users.
DISABILITY AND REHABILITATION-ASSISTIVE TECHNOLOGY
(2023)
Proceedings Paper
Engineering, Biomedical
Jesus de Miguel-Fernandez, Camille Pescatore, Alba Mesa-Garrido, Cindy Rikhof, Erik Prinsen, Josep M. Font-Llagunes, Joan Lobo-Prat
Summary: Recent studies have shown the feasibility of ankle exoskeletons for post-stroke gait rehabilitation. This study developed an ABLE-S exoskeleton that provided time-adapted ankle assistance and conducted comprehensive experimental analysis to evaluate its effects. The results demonstrated significant improvement in gait biomechanics for post-stroke individuals.
2022 9TH IEEE RAS/EMBS INTERNATIONAL CONFERENCE ON BIOMEDICAL ROBOTICS AND BIOMECHATRONICS (BIOROB 2022)
(2022)
Proceedings Paper
Engineering, Biomedical
Cindy J. H. Rikhof, Gerdienke B. Prange-Lasonder, Erik C. Prinsen, Jaap H. Buurke, Johan S. Rietman
Summary: Stroke patients in the sub-acute stage can benefit from robot-supported training and muscle activity-triggered electrostimulation. The method based on resting levels plus two times the standard deviation showed the most consistent movement initiation detection in this small sample of patients.
2022 INTERNATIONAL CONFERENCE ON REHABILITATION ROBOTICS (ICORR)
(2022)
Proceedings Paper
Engineering, Biomedical
Robert V. Schulte, Erik C. Prinsen, Leendert Schaake, Jaap H. Buurke
Summary: Synchronizing motion capture systems with other modalities in out-of-the-lab settings is challenging. The study developed and validated an acceleration based post-measurement method for synchronizing an IMU motion capture system and an EMG measurement device. The results showed that the method works well for different activities.
2022 INTERNATIONAL CONFERENCE ON REHABILITATION ROBOTICS (ICORR)
(2022)
Review
Robotics
Jule Bessler, Gerdienke B. Prange-Lasonder, Robert V. Schulte, Leendert Schaake, Erik C. Prinsen, Jaap H. Buurke
FRONTIERS IN ROBOTICS AND AI
(2020)
