Article
Geriatrics & Gerontology
Andrea Kirfel, Jan Menzenbach, Vera Guttenthaler, Johanna Feggeler, Andreas Mayr, Mark Coburn, Maria Wittmann
Summary: The study aimed to compare the frequency of tested POD with the coded ICD diagnosis of POD and evaluate the impact of POD on ICU and hospital LOS. Results showed that approximately 50% of elderly patients undergoing cardiac surgery developed POD, which was significantly associated with prolonged LOS in ICU and hospital. Additionally, the underdiagnosis of POD in clinical routine was highlighted.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Clinical Neurology
Bianca Fedele, Dean McKenzie, Gavin Williams, Robert Giles, John Olver
Summary: This study explores sleep disturbance in patients with PTA following moderate to severe TBI through ambulatory PSG and salivary melatonin assessment. Findings suggest altered sleep structure and abnormal melatonin levels in these patients, highlighting the need for further research on the relationship between PTA and sleep disturbances.
NEUROREHABILITATION AND NEURAL REPAIR
(2021)
Article
Psychiatry
Kerstin Weber, Sandrine Morier, Lise Lesaffre, Christophe Menu, Philippe Bertschy, Francois R. Herrmann, Panteleimon Giannakopoulos
Summary: This article analyzes the demographic, psychiatric, and offense predictors of length of stay and discharge locations for mentally disordered offenders receiving court-ordered treatments in a new medium-security forensic psychiatry clinic in Geneva, Switzerland.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Rehabilitation
Courtney Spiteri, Jennie Ponsford, Gavin Williams, Michelle Kahn, Adam McKay
Summary: Agitation, fatigue, pain, and cognitive impairment have negative effects on physical therapy participation and outcomes during posttraumatic amnesia after traumatic brain injury.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Rehabilitation
Jennifer A. Weaver, John Liu, Ann Guernon, Theresa Bender Pape, Trudy Mallinson
Summary: The study aimed to investigate the construct validity and measurement precision of the Coma Near-Coma scale in measuring neurobehavioral function in patients with disorders of consciousness. Results showed that the items of the CNC reflected good construct validity and acceptable interrater reliability. The CNC achieved good measurement precision in the full sample.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Review
Critical Care Medicine
Thiago G. Bassi, Elizabeth C. Rohrs, Steven C. Reynolds
Summary: Through a systematic review, it was found that mechanical ventilation may be associated with neuroinflammation, cognitive impairment, and brain insult, but no clinical studies have demonstrated a causal link between MV, cognitive dysfunction, and brain insult. More research should focus on ventilation-induced brain injury pathways and causative linkage.
Article
Anesthesiology
Andrea Kirfel, Vera Guttenthaler, Andreas Mayr, Mark Coburn, Jan Menzenbach, Maria Wittmann
Summary: This study aimed to identify preoperative risk factors and the impact of postoperative delirium (POD) on length of stay in the ICU and hospital for older patients. The results showed that POD was an independent predictor for a prolonged length of stay in the ICU and hospital.
JOURNAL OF ANESTHESIA
(2022)
Article
Anesthesiology
Elzbieta Dulko, Michal Jedrusiak, Hari P. Osuru, Navya Atluri, Meghana Illendula, Eric M. Davis, Mark P. Beenhakker, Nadia Lunardi
Summary: In this study, an animal model was used to investigate the effects of Anesthesia, Surgery, and simulated ICU conditions (ASI) on sleep fragmentation, EEG slowing, and circadian disarray in aged mice. The results showed that ASI mice experienced frequent arousals, EEG slowing, and disrupted circadian gene expression, similar to delirious ICU patients. These findings suggest that the mouse model can be used to study the neurobiology of delirium.
ANESTHESIA AND ANALGESIA
(2023)
Article
Rehabilitation
Christine Yunjae Wang, Marla Petriello, Jiling Chou, Richard David Zorowitz
Summary: This study aimed to compare functional outcomes of acquired brain injury patients in an inpatient rehabilitation facility during the COVID-19 pandemic and before, and found that despite the impact of hospital policies, similar functional outcomes were obtained for those with acquired brain injury after inpatient rehabilitation.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Article
Rehabilitation
Megan Banky, Ross A. Clark, Benjamin F. Mentiplay, John H. Olver, Gavin Williams
Summary: This study found that clinicians often completed the Modified Tardieu Scale too quickly, leading to mismatches with joint angles and angular velocities during walking.
JOURNAL OF REHABILITATION MEDICINE
(2021)
Article
Rehabilitation
Wendy L. Magee, Ajit Narayanan, Rebecca O'Connor, Fiona Haughey, Erin Wegener, Bernice H. L. Chu, Mark Delargy, Dee Gray, Alika D. Seu, Richard J. Siegert, Rosanne J. Tyas, Kudret C. Yelden, Caroline Schnakers
Summary: This study aimed to examine the concurrent validity of the Music Therapy Assessment Tool for Awareness in Disorders of Consciousness (MATADOC) with the criterion standard Coma Recovery Scale-Revised (CRS-R) in patients with prolonged disorders of consciousness (PDoC). The results showed that MATADOC and CRS-R measure similar underlying latent variables of awareness and could complement each other for diagnosis and intervention purposes.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Rehabilitation
Leia Vos, Esther Ngan, Luis Leon Novelo, Michael W. Williams, Flora M. Hammond, William C. Walker, Allison N. Clark, Andrea P. Ochoa Lopez, Shannon B. Juengst, Mark Sherer
Summary: This study analyzed a longitudinal database of traumatic brain injury patients to identify key factors associated with loss to follow-up. Missed earlier follow-ups and demographic factors, including ethnicity, education, and health insurance, were found to be strong predictors of loss to follow-up. Efforts should be made to retain participants from socially disadvantaged or minority groups.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Rehabilitation
Emily L. Morrow, Nirav N. Patel, Melissa C. Duff
Summary: This study investigated the impact of the COVID-19 pandemic on individuals with chronic traumatic brain injury (TBI), finding that individuals with TBI have more difficulties coping with the pandemic, with social isolation and mental health challenges identified as key barriers.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Clinical Neurology
Alissa A. A. Totman, Adam G. G. Lamm, Richard Goldstein, Joseph T. T. Giacino, Yelena G. G. Bodien, Colleen M. M. Ryan, Jeffrey C. C. Schneider, Ross Zafonte
Summary: The study aimed to describe the national trends in inpatient rehabilitation facility (IRF) discharges for the most severely disabled patients with traumatic brain injury (TBI). Data from the Uniform Data System for Medical Rehabilitation were analyzed, and it was found that the number and proportion of TBI patients with the most severe disability admitted to IRFs and discharged from them decreased over time. This decrease may be attributed to primary prevention, early mortality, alternative discharge dispositions, or changes in admitting and reimbursement practices. There was also a decrease in the duration of IRF level care for these patients.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2023)
Article
Neurosciences
Francesca Cesira Cava, Giovanna Barbara Castellani, Elisa Maietti, Pamela Salucci, Valentina Colombo, Giorgio Palandri
Summary: This study designed a new clinical diagnostic protocol to improve the accuracy of secondary hydrocephalus diagnosis in patients with severe acquired brain injuries. The protocol integrates clinical, functional, biochemical, and neuroradiological assessments. Expected results include increased diagnosed cases, reduced clinical complications, improved rehabilitative outcomes, shortened hospital stay, and valuable information about neuroradiological characteristics. The protocol has the potential to improve prognosis and can be adopted by other rehabilitation centers.
