Article
Rehabilitation
Sugalya Amatachaya, Donlaya Promkeaw, Preeda Arayawichanon, Thiwabhorn Thaweewannakij, Pipatana Amatachaya
Summary: Comparing walking training on different surfaces for individuals with SCI can improve their functional ability and reduce fall risk, especially for those who can walk independently. The experimental group showed significant improvement after training, with a lower fall rate compared to the control group.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Rehabilitation
Mei Zhen Huang, Mark W. Rogers, Douglas Pizac, Ann L. Gruber-Baldini, Denise Orwig, Marc C. Hochberg, Brock A. Beamer, Robert A. Creath, Douglas N. Savin, Vincent M. Conroy, Kathleen K. Mangione, Rebecca Craik, Li-Qun Zhang, Jay Magaziner
Summary: The objective of this study was to investigate the effect of 16-week home-based physical therapy interventions on gait and muscle strength. The study found that both the experimental and control groups showed significant increases in usual and fast walking speed after the intervention. However, there was no significant difference in the increases between the groups. The study also showed that the experimental group had a significant improvement in lower limb muscle strength compared to the control group.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Orthopedics
Rodrigo Rodrigues Gomes Costa, Frederico Ribeiro Neto, Carlos Wellington Goncalves, Rodrigo Luiz Carregaro
Summary: The study investigated the accuracy of different forms of muscle knee extension strength analysis to identify high or low walking performance in individuals with chronic stroke. The results showed that the models using the difference between sides (DS) and the sum of the sides (SS) of knee extension strength had moderate accuracy in predicting walking performance. Time since injury and peak torque also played important roles in predicting walking performance.
BRAZILIAN JOURNAL OF PHYSICAL THERAPY
(2021)
Article
Cell Biology
Hiroki Okawara, Syoichi Tashiro, Tomonori Sawada, Keiko Sugai, Kohei Matsubayashi, Michiyuki Kawakami, Satoshi Nori, Osahiko Tsuji, Narihito Nagoshi, Morio Matsumoto, Masaya Nakamura
Summary: Body weight-supported treadmill training with the voluntary driven exoskeleton (VDE-BWSTT) has been shown to improve the gait function of patients with chronic spinal cord injury. This study indicates that VDE-BWSTT can effectively improve the trunk function of patients with chronic spinal cord injury, especially for older adult patients.
NEURAL REGENERATION RESEARCH
(2022)
Article
Geriatrics & Gerontology
R. S. Feitosa, A. C. B. Marini, G. D. Pimentel
Summary: This study examined the prevalence of sarcopenia in elderly hemodialysis patients and found an association between fat mass percentage and SARC-F/SARC-F+CC. A significant proportion (37.5%) of patients were at risk of muscle function loss, and adiposity was linked to an increased likelihood of sarcopenia by 25%.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Engineering, Biomedical
Andrew Sawers, Stefania Fatone
Summary: The purpose of this study was to test whether there were differences in hip strength between the residual and intact limbs of lower limb prosthesis users. The results suggest that the intact limb is weaker compared to the residual limb, which may be due to methodological choices or biomechanical demands on the residual limb hip muscles. Further research is needed to confirm, expand upon, and elucidate the findings, as well as clarify the contributions of intact and residual limb hip muscles to walking and balance in lower limb prosthesis users.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2023)
Article
Nutrition & Dietetics
Feng-Min Zhang, Xian-Zhong Zhang, Han-Ping Shi, Zhao Zhang, Su-Lin Wang, Zi-Le Shen, Xiao-Lei Chen, Xian Shen, Zhen Yu, Cheng-Le Zhuang
Summary: Muscle function parameters (such as handgrip strength and gait speed) are better predictors of post-operative complications and survival compared to muscle composition parameters. Combining muscle function and muscle composition separately in the sarcopenia definition is more effective than combining two muscle function parameters or two muscle composition parameters.
FRONTIERS IN NUTRITION
(2021)
Article
Nutrition & Dietetics
Amir Bagheri, Rezvan Hashemi, Ramin Heshmat, Ahmadreza Dorosty Motlagh, Ahmad Esmaillzadeh
Summary: The study identified three major nutrient-based dietary patterns associated with sarcopenia and its components. The anti-inflammatory pattern was inversely related to the odds of sarcopenia and low muscle strength, while the carbo-vit pattern was inversely associated with the odds of low gait speed. Further research is needed to confirm these findings.
FRONTIERS IN NUTRITION
(2021)
Article
Medicine, General & Internal
Byung Hoon Kwack, Jun Chul Kim, Jun Young Do, Seok Hui Kang
Summary: The study found a higher correlation of the NPM index with muscle mass-related indices compared to the PM index, and it had stronger predictive value for SGA score, ASM/Ht(2), HGS, and GS. The NPM index may be an early and useful indicator for detecting muscle strength and physical performance among HD patients.
FRONTIERS IN MEDICINE
(2021)
Article
Engineering, Biomedical
Raiff Simplicio da Silva, Mikhail Santos Cerqueira, Daniel Germano Maciel, Stephano Tomaz da Silva, Marianna Celeste Cordeiro de Figueiredo, Daiane Carla Rodrigues Cardoso, Sinval Bezerra Nobrega Neto, Clarissa Fernandes Bezerra, Rafael Pereira, Wouber Herickson de Brito Vieira, Tatiana Souza Ribeiro
Summary: This study verified the relationship between walking speed and neuromuscular parameters in stroke survivors and found that adjusting predictive models for assistive device use and lower limb motor function improves accuracy. These findings may have significant implications for assessing stroke individuals and developing treatment strategies.
CLINICAL BIOMECHANICS
(2022)
Article
Geriatrics & Gerontology
Juan Luis Sanchez-Sanchez, L. He, K. Virecoulon Giudici, S. Guyonnet, A. Parini, C. Dray, P. Valet, O. Pereira, B. Vellas, Y. Rolland, P. de Souto Barreto
Summary: This study found that blood apelin and GDF-15 were not significantly associated with the incidence of age-related sarcopenia or the evolution of sarcopenia components in older adults over a 2-year follow-up period.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Chemistry, Analytical
Julio A. Costa, Konstantinos Spyrou, Antonio Sancho, Joana F. Reis, Joao Brito
Summary: A study was conducted to assess the reliability of measuring maximal strength and rate of force development during the Nordic hamstring exercise (NHE). The results showed no significant differences in the test-retest measurements of maximal strength and rate of force development after a two-day interval.
Article
Geriatrics & Gerontology
Adam J. Santanasto, Joseph M. Zmuda, Ryan K. Cvejkus, Christopher L. Gordon, Sangeeta Nair, J. Jeffrey Carr, James G. Terry, Victor W. Wheeler, Iva Miljkovic
Summary: This study examined the association between myosteatosis and physical function in African Caribbean men. The results showed that myosteatosis in the calf and thigh was strongly associated with grip strength and performance measures of physical function, while myosteatosis in the abdomen may have some utility when abdominal images are all that are available.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Review
Geriatrics & Gerontology
Jinyang Zhuang, Jie Jia
Summary: This article reviews the research progress of respiratory muscle strength training (RMST) in Parkinson's disease (PD) rehabilitation, providing new insights into the management of respiratory-related impairments in people with PD.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Rheumatology
Toby O. Smith, Celia Clarke, Jack R. Dainty, Laura Watts, Max Yates, Valerie M. Pomeroy, Emma Stanmore, Terence W. O'Neill, Alexander J. Macgregor
Summary: The study aimed to identify the clinical and biomechanical characteristics associated with falls in people with rheumatoid arthritis (RA). Results showed that older age, unmarried status, higher pain scores, frequent dizziness, psychotropic medication usage, and lower health-related quality of life (HRQoL) were associated with falls in RA patients. Biomechanical assessments revealed that fallers had greater anteroposterior and medial-lateral sway range, reduced knee flexion strength, shorter stride length, shorter double support time, and decreased knee range of motion during the gait cycle compared to non-fallers.
Review
Rehabilitation
Cecilie Thrue, Lars G. Hvid, Mads Gamborg, Helen Dawes, Ulrik Dalgas, Martin Langeskov-Christensen
Summary: This study systematically reviewed the psychometric properties of the VO2max test in PD, VO2max levels in pwPD compared to HCs, and reported VO2max associations in PD. The results showed that VO2max was comparable between pwPD and HC as well as between different PD-medication states, and only age, sex, and fatigue were associated with VO2max. However, there was limited evidence on the psychometric properties of the VO2max test.
DISABILITY AND REHABILITATION
(2023)
Article
Rehabilitation
Anders Gravholt, Jon Herskind, Christoffer Tiedemann Kloster, Lars G. Hvid, Kristian Overgaard
Summary: The objective of this study was to investigate the effects of electrical stimulation current, pulse frequency, and contraction mode on torque output and discomfort, as well as the influence of familiarization on perceived discomfort ratings. The results showed that a higher stimulation frequency increased torque without increasing discomfort, while higher currents were associated with increases in both torque and discomfort. Contraction type did not affect discomfort levels, although eccentric contractions produced higher torque compared to concentric and isometric contractions. Additionally, a single familiarization session significantly reduced perceived discomfort during electrical stimulation.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Review
Clinical Neurology
Mads Gamborg, Lars Grondahl Hvid, Cecilie Thrue, Sverker Johansson, Erika Franzen, Ulrik Dalgas, Martin Langeskov-Christensen
Summary: This study systematically reviewed the literature on mechanical muscle function in people with Parkinson's disease (PwPD). The findings indicate that PwPD have impaired muscle strength, power, and rate of force development compared to healthy controls (HC). Additionally, muscle strength was found to be associated with functional capacity and disease severity.
JOURNAL OF NEUROLOGIC PHYSICAL THERAPY
(2023)
Article
Clinical Neurology
Paolo Preziosa, Maria A. Rocca, Elisabetta Pagani, Paola Valsasina, Maria Pia Amato, Giampaolo Brichetto, Nicolo Bruschi, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John DeLuca, Rachel Farrell, Peter Feys, Jennifer Freeman, Matilde Inglese, Alessandro Meani, Cecilia Meza, Robert W. Motl, Amber Salter, Brian M. Sandroff, Anthony Feinstein, Massimo Filippi
Summary: The study explores the associations among fatigue, dual-task performance and structural and functional abnormalities of frontal cortico-subcortical network in progressive multiple sclerosis (PMS). The results indicate that both structural and functional abnormalities contribute to fatigue and worse dual-task performance in PMS, with different patterns according to the presence of fatigue.
JOURNAL OF NEUROLOGY
(2023)
Review
Clinical Neurology
John Brincks, Ulrik Dalgas, Erika Franzen, Jacob Callesen, Andreas Wallin, Sverker Johansson
Summary: The specific components of balance training interventions in people with multiple sclerosis (PwMS) were systematically analyzed. The frequency, time, and duration of the interventions were well described, while the intensity and progression of training were not reported systematically. The interventions primarily focused on sensory and motor strategies, with little emphasis on reactive motor strategies, vestibular sense, and cognitive dual-tasking.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2023)
Article
Physiology
Ole Emil Andersen, Anders M. Kristensen, Ole B. Nielsen, Kristian Overgaard
Summary: This study aimed to investigate the acute effects of muscle activity on eccentric force of slow and fast-twitch muscles and its relation to postactivation potentiation. The results showed that muscle force consistently increased during consecutive contractions while isometric peak force slightly declined. This increase in eccentric force may be important for sports performance.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Luise Aamann, Gitte Dam, Peter Jepsen, Mette Borre, Aska Drljevic-Nielsen, Kristian Overgaard, Henning Andersen, Hendrik Vilstrup, Niels Kristian Aagaard
Summary: This study investigates whether a 12-week period of resistance training has a long-term effect on the risk of hospitalization or mortality among patients with cirrhosis. The results show that the training group has a lower risk of first hospitalization and lower all-cause mortality. This suggests that resistance training may reduce the risk of hospitalization and death in patients with cirrhosis.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Clinical Neurology
Frederik Bonde Jensen, Ulrik Dalgas, John Brincks, Martin Langeskov-Christensen
Summary: This study investigated the content validity and test-retest reliability of the VO2-max test in persons with Parkinson's disease (pwPD), both in the ON and OFF medication states. The study found that the VO2-max test had acceptable content validity and excellent day-to-day reliability in pwPD, regardless of medication.
PARKINSONISM & RELATED DISORDERS
(2023)
Article
Sport Sciences
Lisa Urup Tonning, Bjarne Mygind-Klavsen, Troels Kjeldsen, Ulrik Dalgas, John Brincks, Inger Mechlenburg
Summary: Chronic exertional compartment syndrome (CECS) is a common cause of exercise-induced pain in the lower leg. This study compared muscle strength, oxygen saturation, and daily physical activity between patients with CECS and asymptomatic controls. The results showed no differences in muscle strength, oxygen saturation, and daily physical activity levels between the two groups, but patients with CECS experienced significantly higher levels of lower leg pain during running and daily activities. Oxygen saturation was not associated with leg pain.
INTERNATIONAL JOURNAL OF SPORTS PHYSICAL THERAPY
(2023)
Review
Physiology
Jean-Marc Renaud, Niels ortenblad, Michael J. McKenna, Kristian Overgaard
Summary: Potassium ions play a crucial role in skeletal muscle fatigue, but the changes in K+ intra-to-extracellular gradient alone are not enough to cause significant force decrease unless combined with changes in other ion gradients, such as Na+. Studies have shown that K+-induced force depression can be prevented by decreased ClC-1 channel activity, allowing K+-induced potentiation to dominate during low-moderate intensity muscle contractions. However, during metabolic stress, both K-ATP and ClC-1 channels are activated, leading to force reductions and fatigue.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Review
Clinical Neurology
Marcia Finlayson, Peter Feys, Ulrik Dalgas, Daphne Kos
Summary: This study discusses the conceptual and practical issues related to selecting intermediate outcomes for clinical trials of multiple sclerosis (MS) rehabilitation interventions. The overall goal of rehabilitation is optimal functioning, which is a complex biopsychosocial phenomenon that varies with patient priorities and environmental context. Multiple causal pathways and potential intermediate outcomes must be carefully considered in the design of clinical trials aiming to improve functioning in MS rehabilitation, along with practical issues such as the psychometric properties of outcome measures, measure type, and characteristics of the target population, including severity of dysfunction.
MULTIPLE SCLEROSIS JOURNAL
(2023)
Article
Clinical Neurology
Nick M. Kristensen, Laurits Taul-Madsen, Tobias Gaemelke, Morten Riemenschneider, Ulrik Dalgas, Lars G. Hvid
Summary: This study investigated the association between rate of force development (RFD) and falls in persons with multiple sclerosis (pwMS). The findings suggest that RFD is superior to maximal muscle strength (Fmax) in discriminating fallers from non-fallers in pwMS. Therefore, assessing lower extremity neuromuscular function may be useful in identifying pwMS at future risk of falling.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2023)
Article
Clinical Neurology
Morten Riemenschneider, Lars G. G. Hvid, Thor Petersen, Egon Stenager, Ulrik Dalgas
Summary: This study investigates the effects of exercise on physical function, cognition, and patient-reported measures of disease and fatigue impact in early multiple sclerosis (MS). The results show that supervised aerobic exercise can improve physical function, but does not have a significant impact on cognitive function. However, perception of disease and fatigue impact can be improved through exercise in early MS.
NEUROREHABILITATION AND NEURAL REPAIR
(2023)
Article
Clinical Neurology
Anders G. Skjerbaek, Ulrik Dalgas, Egon Stenager, Finn Boesen, Lars G. Hvid
Summary: Walking capacity is crucial for individuals with multiple sclerosis. This study compared impairment levels across three commonly used walking capacity outcomes in multiple sclerosis patients. The results showed that patients with multiple sclerosis performed worse than healthy controls in all three outcomes, with differences observed between the different outcomes.
MULTIPLE SCLEROSIS JOURNAL-EXPERIMENTAL TRANSLATIONAL AND CLINICAL
(2023)
Article
Clinical Neurology
Anthony Feinstein, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy Chiaravalloti, Gary Cutter, Ulrik Dalgas, John DeLuca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Robert W. Motl, Maria A. Rocca, Brian M. Sandroff, CogEx Res Team
Summary: This study investigated the individual and synergistic effects of cognitive rehabilitation and exercise in patients with progressive multiple sclerosis. The results showed that combined cognitive rehabilitation plus exercise did not seem to improve processing speed in these patients.