Article
Clinical Neurology
Mathew J. Reeves, Bernadette Boden-Albala, Dominique A. Cadilhac
Summary: In many countries, most of a person's recovery from stroke occurs in the community, as the hospital stay after an acute stroke admission is typically short. Care transitions, such as transferring between care settings or providers, pose challenges and vulnerability for stroke patients and caregivers. Underserved and minority populations, due to exposure to poor conditions and discrimination, are particularly susceptible to complicated care transitions, which can negatively impact stroke recovery. Evidence on how to support post-acute stroke care, especially for underserved communities, remains limited.
Article
Geriatrics & Gerontology
Marten Segerdahl, Per-Olof Hansson, Carina M. Samuelsson, Carina U. Persson
Summary: This study found that four out of five stroke survivors (79%) reported impaired HRQoL five years after stroke, with pain/discomfort being the main issue. Higher age and longer hospital stay during the index stroke were associated with impaired HRQoL.
Review
Clinical Neurology
Sarah A. Moore, Pierce Boyne, George Fulk, Geert Verheyden, Natalie A. Fini
Summary: This narrative review explores the current state of walking recovery research after stroke and its potential for development. The importance of targeting walking capacity and performance in relation to individual stroke survivor gait recovery is discussed, along with the need for a common language, measurement, classification, prediction, and current and future intervention development and healthcare delivery. The findings are summarized in a model of current and future stroke walking recovery research, and a mission statement is set to drive the field forward and improve the lives of stroke survivors and their caregivers.
Article
Rehabilitation
Winke Van Meijeren-Pont, Sietske J. Tamminga, Paulien H. Goossens, Iris F. Groeneveld, Henk Arwert, Jorit J. L. Meesters, Radha Rambaran Mishre, Thea P. M. Vlieland, Wilbert B. van den Hout
Summary: The study estimated societal costs and changes in health-related quality of life in stroke patients up to one year after the start of medical specialist rehabilitation. It found that one-year societal costs were considerable, and for inpatients, health-related quality of life significantly improved over time.
JOURNAL OF REHABILITATION MEDICINE
(2021)
Article
Rehabilitation
Julie A. DiCarlo, Galina Gheihman, David J. Lin
Summary: This study conducted a multidisciplinary interactive workshop to identify major challenges facing stroke recovery and proposed unique solutions, including new technologies, healthcare system changes, and the creation of new support roles. Analysis revealed that a comprehensive stroke clinic with follow-up programs, cutting edge treatments, patient advocation, and research was the single proposed solution that solved the most identified challenges.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Review
Medicine, General & Internal
Bei-lei Lin, Yong-xia Mei, Wen-na Wang, Shan-shan Wang, Ying-shuang Li, Meng-ya Xu, Zhen-xiang Zhang, Yao Tong
Summary: Understanding the unmet needs of community-dwelling stroke survivors is crucial for intervention. A systematic review summarised their unmet needs quantitatively, revealing high prevalence of issues related to information support, physical function, and mental health. Standard, effective tools for assessing unmet needs are essential for addressing these concerns.
Article
Clinical Neurology
Joosup Kim, Dominique A. Cadilhac, Stephanie Thompson, John Gommans, Alan Davis, P. Alan Barber, John Fink, Matire Harwood, William Levack, Harry McNaughton, Virginia Abernethy, Jacqueline Girvan, Valery Feigin, Hayley Denison, Marine Corbin, Andrew Wilson, Jeroen Douwes, Anna Ranta
Summary: This study compared the costs and quality-adjusted life years of stroke patients admitted to urban and nonurban hospitals in New Zealand. The results showed that urban hospitals had higher treatment costs and quality-adjusted life years compared to nonurban hospitals, even after adjustment for other factors. These findings can help improve the level of treatment in nonurban hospitals and optimize outcomes for patients.
Article
Medicine, General & Internal
Cristina Fernandez-Garcia, Laura Ternent, Tara Marie Homer, Helen Rodgers, Helen Bosomworth, Lisa Shaw, Lydia Aird, Sreeman Andole, David Cohen, Jesse Dawson, Tracy Finch, Gary Ford, Richard Francis, Steven Hogg, Niall Hughes, H. Krebs, Christopher Price, Duncan Turner, Frederike Van Wijck, Scott Wilkes, Nina Wilson, Luke Vale
Summary: The study found that neither robot-assisted training nor EULT were likely to be cost-effective compared to usual care in terms of healthcare resource use and QALYs. Although EULT group had the highest QALYs value among participants, it did not show better cost-effectiveness compared to robot-assisted training or usual care.
Article
Environmental Sciences
Masashi Kanai, Kazuhiro P. Izawa, Hiroki Kubo, Masafumi Nozoe, Kyoshi Mase, Shinichi Shimada
Summary: This study investigated the association between health utility score and physical activity outcomes in stroke survivors, finding that the health utility score was significantly associated with the number of steps taken, but not with the duration of moderate-to-vigorous physical activity (MVPA).
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Yi Wang, Shilpa Tyagi, Helen Hoenig, Kim En Lee, Narayanaswamy Venketasubramanian, Edward Menon, Deidre Anne De Silva, Philip Yap, Boon Yeow Tan, Sherry H. Young, Yee Sien Ng, Tian Ming Tu, Yan Hoon Ang, Keng He Kong, Rajinder Singh, Reshma A. Merchant, Hui Meng Chang, Chou Ning, Angela Cheong, Gerald Choon-Huat Koh
Summary: Informal care burden remains high up to 12-months post-stroke, with factors such as functional dependency, stroke severity, informal caregiver gender, and co-caring with foreign domestic workers being associated with informal care burden.
Article
Medicine, General & Internal
Caroline Bulsara, Rosemary Saunders, Laura Emery, Christopher Etherton-Beer
Summary: This study identified barriers and enablers to care experiences from the perspectives of stroke survivors, carers, and staff. Findings showed a mismatch between staff and patient/family expectations, but highlighted the positive impact of specialized rehabilitation units on patient experience. Further research with diverse hospital settings is needed to address rehabilitation care reality and patient readiness when returning home.
Article
Multidisciplinary Sciences
Amy F. Dennett, Judi Porter, Stephen Ting, Nicholas Taylor
Summary: This study aims to explore the efficacy of prehabilitation in improving physical capacity for people undergoing autologous stem cell transplant. The intervention includes exercise and nutrition education, and the results will assess changes in physical capacity, time to engraftment, self-efficacy, and adverse events.
Article
Clinical Neurology
Boback Ziaeian, Haolin Xu, Roland A. Matsouaka, Ying Xian, Yosef Khan, Lee S. Schwamm, Eric E. Smith, Gregg C. Fonarow
Summary: We provide timely, reliable, and actionable US national surveillance data for acute ischemic stroke (AIS) using Bayesian interpolation poststratification weights, which can contribute to quality improvement in stroke care and outcomes.
Review
Medicine, General & Internal
Sarah E. Hughes, Olalekan Lee Aiyegbusi, Daniel S. Lasserson, Philip Collis, Samantha Cruz Rivera, Christel McMullan, Grace M. Turner, Jon Glasby, Melanie Calvert
Summary: PROs are measures of a person's views on their health and quality of life, typically assessed through self-completed questionnaires known as PROMs. While they have potential in social care, their current use in this context is unclear.
Article
Cardiac & Cardiovascular Systems
Kelly L. Sloane, Scott E. Kasner, Christopher G. Favilla, Aaron Rothstein, Jens Witsch, Roy H. Hamilton, Andrea L. C. Schneider
Summary: This study investigates the roles of optimism and depression in stroke recovery and finds that patients who are optimistic and without depression have the best recovery, while patients who lack optimism and have depression have the slowest recovery.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Rehabilitation
Yi-Jing Huang, Gong-Hong Lin, Ya-Chen Lee, Tzu-Yi Wu, Wen-Hsuan Hou, Ching-Lin Hsieh
Summary: This study aimed to develop a computerized adaptive test to efficiently assess health literacy among patients with stroke. The results showed that the computerized adaptive test displayed suitable reliability in all 12 health literacy domains, with a relatively short test length.
DISABILITY AND REHABILITATION
(2022)
Article
Rehabilitation
Gong-Hong Lin, Chih-Ying Li, Ching-Fan Sheu, Chien-Yu Huang, Shih-Chieh Lee, Yu-Hui Huang, Ching-Lin Hsieh
Summary: This study aimed to develop and validate a machine learning-based short measure (ML-5F) for assessing five functions in stroke patients. The ML-5F, consisting of 15 selected items transformed into scores using the Extreme Gradient Boosting algorithm, demonstrated good concurrent validity and responsiveness. It has the potential to be an efficient outcome measure in clinical settings for evaluating activities of daily living, balance, upper extremity and lower extremity motor function, and mobility in stroke patients.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Neuroimaging
Shin-Joe Yeh, Chih-Hao Chen, Yen-Heng Lin, Li-Kai Tsai, Chung-Wei Lee, Sung-Chun Tang, Jiann-Shing Jeng
Summary: Our findings demonstrate that plasma levels of SAA at an early stage are significant predictors for poor functional outcomes at 3 months in patients with stroke receiving EVT, indicating the substantial role of systemic inflammation in shaping stroke outcomes following EVT.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Medicine, General & Internal
Yu-Lun Chen, Nai-Fang Chi, Hung-Yi Chiou, Chaur-Jong Hu, Jiann-Shing Jeng, Sung-Chun Tang, Huey-Juan Lin, Yi-Chen Hsieh
Summary: This study developed a polygenic risk score for hyperglycemia/diabetes to predict poor outcomes after a stroke. The score improved the prediction performance and had potential clinical applications.
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION
(2022)
Article
Medicine, General & Internal
Chuan-Hsiu Fu, Chih-Hao Chen, Chun-Hsien Lin, Chung-Wei Lee, Meng Lee, Sung-Chun Tang, Jiann-Shing Jeng
Summary: This study compared the performance of multiple risk scores in predicting symptomatic intracerebral hemorrhage (SICH) after endovascular treatment (EVT). The results showed that the SEDAN and TAG scores consistently predicted SICH and exhibited higher accuracy under certain criteria. Higher glucose level and unsuccessful recanalization were identified as independent risk factors. These findings have important implications for improving the prediction and prevention of SICH.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
(2022)
Article
Multidisciplinary Sciences
Ming-Chyi Pai, Chau-Chung Wu, Yi-Chou Hou, Jiann-Shing Jeng, Sung-Chun Tang, Wei-Che Lin, Cheng-Hsien Lu, Ming-Jang Chiu, Ta-Fu Chen, Sui-Hing Yan, Chaur-Jong Hu, Shieh-Yueh Yang
Summary: Patients with comorbidities are at risk for neurodegeneration. A study found significantly higher levels of plasma A beta(1-42) and T-Tau in patients with poststroke, family history of Alzheimer's disease, diabetes, end-stage renal disease, and obstructive sleep apnea.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Chin-Feng Hsuan, Fang-Ju Lin, Thung-Lip Lee, Kai-Chien Yang, Wei-Kung Tseng, Yen-Wen Wu, Wei-Hsian Yin, Hung- Yeh, Jaw-Wen Chen, Chau-Chung Wu
Summary: The waist-to-BMI ratio may serve as a significant predictor for the risk of major adverse cardiovascular events (MACE) in patients with established ASCVD.
SCIENTIFIC REPORTS
(2022)
Article
Clinical Neurology
Chih-Hao Chen, Sung-Chun Tang, Yu-Wei Chen, Chih-Hung Chen, Li-Kai Tsai, Sheng-Feng Sung, Huey-Juan Lin, Hung-Yu Huang, Helen L. Po, Yu Sun, Po-Lin Chen, Lung Chan, Cheng-Yu Wei, Jiunn-Tay Lee, Cheng-Yang Hsieh, Yung-Yang Lin, Li-Ming Lien, Jiann-Shing Jeng
Summary: The efficacy and safety of standard-dose and low-dose alteplase administered 3-4.5 hours after acute ischemic stroke appear to be comparable. Standard-dose alteplase may be preferred for patients with cardioembolism, atrial fibrillation, or hypercholesterolemia.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Nawaf Yassi, Henry Zhao, Leonid Churilov, Bruce C. Campbell, Teddy Wu, Henry Ma, Andrew Cheung, Timothy Kleinig, Helen Brown, Philip Choi, Jiann-Shing Jeng, Annemarei Ranta, Hao-Kuang Wang, Geoffrey C. Cloud, Rohan Grimley, Darshan Shah, Neil Spratt, Der-Yang Cho, Karim Mahawish, Lauren Sanders, John Worthington, Ben Clissold, Atte Meretoja, Vignan Yogendrakumar, Mai Duy Ton, Duc Phuc Dang, Nguyen Thai My Phuong, Huy-Thang Nguyen, Chung Y. Hsu, Gagan Sharma, Peter J. Mitchell, Bernard Yan, Mark W. Parsons, Christopher Levi, Geoffrey A. Donnan, Stephen M. Davis
Summary: The STOP-MSU trial aims to investigate the effectiveness of tranexamic acid in reducing hematoma growth in patients with intracerebral hemorrhage. The study will be conducted in mobile stroke units and emergency departments, with an expected sample size of 180 patients.
STROKE AND VASCULAR NEUROLOGY
(2022)
Article
Rehabilitation
Gong-Hong Lin, Inga Wang, Shih-Chieh Lee, Chien-Yu Huang, Yi-Ching Wang, Ching-Lin Hsieh
Summary: The study developed and validated a shortened form of the Fugl-Meyer Assessment of Upper Extremity Scale (FMA-UE) using a machine learning approach (FMA-UE-ML). Through data analysis, it was determined that there were significant differences among different versions of FMA-UE-ML, with a 13-item version selected as the final version. The FMA-UE-ML demonstrated good concurrent validity and responsiveness, and it can provide all item scores of the FMA-UE for users.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Neuroimaging
Kuo-Wei Chen, Chih-Hao Chen, Yen-Heng Lin, Chung-Wei Lee, Kun-Chang Tsai, Li-Kai Tsai, Sung-Chun Tang, Jiann-Shing Jeng
Summary: This study investigated the outcome of endovascular thrombectomy in patients with end-stage renal disease (ESRD). The results showed that ESRD-dialysis patients had more adverse events and worse outcomes. Patients with premorbid functional dependency also had a higher mortality rate.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2022)
Article
Rehabilitation
Hsin-yu Chiang, Po-Ting Chen, Shih-Chieh Lee, Yun-Jer Shieh, I. -Ping Hsueh, Ching-Lin Hsieh
Summary: The study found that the Computerized Adaptive Test of Social Functioning (Social-CAT) is a reliable and efficient measure with good test-retest reliability, small random measurement error, and good responsiveness. It is therefore a useful outcome measure for routine monitoring of social function changes in patients with stroke.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Clinical Neurology
Bo-Ching Lee, Hsin-Hsi Tsai, Chia-Ju Liu, Ya-Fang Chen, Li-Kai Tsai, Jiann-Shing Jeng, Ruoh-Fang Yen
Summary: This study found that cerebral venous reflux (CVR) is more closely associated with cerebral amyloid angiopathy (CAA) than hypertensive microangiopathy in intracerebral hemorrhage (ICH) survivors. The results suggest that venous drainage dysfunction potentially plays a role in CAA and cerebral amyloid deposition.
Article
Rehabilitation
Po-Ting Chen, Shih-Chie Lee, Tzu-Yi Wu, Meng-Lin Lee Md, Ching-Lin Hsieh
Summary: This study examined the test-retest reliability, responsiveness, and clinical utility of the Computerized Adaptive Testing System of the Functional Assessment of Stroke (CAT-FAS) in persons with stroke. The results indicated that CAT-FAS is an efficient measurement tool with good to excellent test-retest reliability and responsiveness. It can be used routinely in clinical settings to monitor the progress of stroke patients.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
