Article
Respiratory System
Narelle S. Cox, Christine F. McDonald, Ajay Mahal, Jennifer A. Alison, Richard Wootton, Catherine J. Hill, Paolo Zanaboni, Paul O'Halloran, Janet Bondarenko, Heather Macdonald, Kathryn Barker, Hayley Crute, Christie Mellerick, Bruna Wageck, Helen Boursinos, Aroub Lahham, Amanda Nichols, Pawel Czupryn, Monique Corbett, Emma Handley, Angela T. Burge, Anne E. Holland
Summary: The study found no significant differences between center-based pulmonary rehabilitation and telerehabilitation for both primary and secondary outcomes at the end of rehabilitation and at the 12-month follow-up. Although equivalence of telerehabilitation for CRQ-D was not confirmed, it showed equivalence in 6-minute walk distance at the end of rehabilitation and possibly had superiority at 12 months.
Article
Respiratory System
Henrik Hansen, Andre Torre, Thomas Kallemose, Charlotte Suppli Ulrik, Nina Skavlan Godtfredsen
Summary: This study analyzed the proportion of minimal important changes in patients with COPD who received home-based pulmonary telerehabilitation (PTR) or traditional hospital-based outpatient pulmonary rehabilitation (PR). The results showed no significant difference in the improvement of walking distance between home-based PTR and traditional PR at 10 and 62 weeks. While home-based PTR is an effective alternative, outpatient PR remains the preferred option.
Review
Respiratory System
Daniel Taylor, Alex R. Jenkins, Kate Parrott, Alex Benham, Samantha Targett, Arwel W. Jones
Summary: This review found that unsupervised exercise interventions have clinical benefits on health-related quality of life in COPD patients, but more high-quality randomized trials are needed to further validate their effectiveness.
Article
Rehabilitation
Meghan Fahey, Gabrielle Brazg, Christopher E. Henderson, Abbey Plawecki, Emily Lucas, Darcy S. Reisman, Brian D. Schmit, T. George Hornby
Summary: Research in animal models and patients with stroke or iSCI suggests that specific physical training variables, including exercise intensity, can have a significant impact on neurological recovery and locomotor function. Properly defining and ensuring appropriate levels of exercise intensity is crucial for maximizing rehabilitation outcomes in patients with neurologic injury.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Review
Sport Sciences
Ricardo Borges Viana, Vinnycius Nunes de Oliveira, Scott J. Dankel, Jeremy P. Loenneke, Takashi Abe, Wellington Fernando da Silva, Naiane Silva Morais, Rodrigo Luiz Vancini, Marilia Santos Andrade, Claudio Andre Barbosa de Lira
Summary: This systematic review and meta-analysis found that exergames may improve muscle strength in individuals with different health statuses, particularly in handgrip strength and knee extension MVIC. However, the effects on middle age/older adults were not significant, while exergames showed promising results in improving handgrip strength in children with hemiplegic cerebral palsy. Future research with high methodological quality and large sample sizes are needed to further explore the effects and design principles of exergame interventions.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2021)
Article
Clinical Neurology
Christopher E. Henderson, Abbey Plawecki, Emily Lucas, Jennifer K. Lotter, Molly Scofield, Angela Carbone, Jeong H. Jang, T. George Hornby
Summary: The study compared the effectiveness of high-intensity training (HIT) to usual care during inpatient rehabilitation post-stroke. Efforts to prioritize walking and reach higher intensities during HIT led to increased steps/day, resulting in greater gains in locomotor and non-locomotor outcomes.
NEUROREHABILITATION AND NEURAL REPAIR
(2022)
Article
Geriatrics & Gerontology
Charlie C. Hall, Richard J. E. Skipworth, Honor Blackwood, Duncan Brown, Jane Cook, Katharina Diernberger, Elizabeth Dixon, Valerie Gibson, Catriona Graham, Peter Hall, Erna Haraldsdottir, Jane Hopkinson, Anna Lloyd, Matthew Maddocks, Lucy Norris, Sharon Tuck, Marie T. Fallon, Barry J. A. Laird
Summary: Despite limited evidence supporting rehabilitation for people with incurable cancer, this trial showed that an exercise and nutrition based rehabilitation programme is feasible and may have potential benefits for this population. Further larger trials are warranted to test the efficacy of this approach.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Review
Rehabilitation
Jorge Motta Anjos, Mansueto Gomes Neto, Franciele Silva dos Santos, Katna de Oliveira Almeida, Edimar Alcides Bocchi, Yasmin de Souza Lima Bitar, Andre Rodrigues Duraes
Summary: High-intensity interval training has positive effects on the functioning and health-related quality of life of post-stroke patients. It improves cardiorespiratory fitness, balance, and gait speed, leading to better physical function in these patients.
CLINICAL REHABILITATION
(2022)
Article
Cardiac & Cardiovascular Systems
Elizabeth W. Regan, Reed Handlery, Jill C. Stewart, Joseph L. Pearson, Sara Wilcox, Stacy Fritz
Summary: This study integrated survivors of stroke into a standard exercise-based CR program and evaluated the impact through physical function measures and qualitative assessment. Results showed that exercise-based CR could significantly improve cardiovascular endurance, health status, and quality of life for survivors of stroke.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Medicine, General & Internal
Victoria Maria Garcia de Medeiros, Jessica Goncalves de Lima, Claudia Rosa, Juliana Rega, Mauro Felippe Felix Mediano, Luiz Fernando Rodrigues Junior
Summary: This study conducted a systematic review of literature to identify physiotherapeutic strategies used in the treatment of patients with Lymphangioleiomyomatosis (LAM). Endurance and resistance training were found to be key in improving lung function, functional capacity, depression symptoms, and quality of life in LAM patients. However, there is still a lack of research regarding the modalities, safety, and dosage of physiotherapy prescription for LAM patients.
ANNALS OF MEDICINE
(2022)
Article
Oncology
Amy M. Dennett, Bernadette Zappa, Rachel Wong, Stephen B. Ting, Kimberley Williams, Casey L. Peiris
Summary: Implementing exercise-based rehabilitation in a co-located cancer unit was found to be safe and feasible, with participants showing significant improvements in function and quality of life. Particularly, participants opting for a twice-weekly hospital-based exercise program reported high satisfaction and no major adverse events.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Oncology
Jiin Ryu, Eun-Young Lee, Jihee Min, Sujin Yeon, Ji-Won Lee, Sang Hui Chu, Hyangkyu Lee, Seung Il Kim, Jee Ye Kim, Seho Park, Justin Y. Jeon
Summary: This 12-month randomized controlled trial investigates the effects of tailored home-based exercise programs on short-term and long-term physiological outcomes in patients with breast cancer. The study found that exercise interventions customized to patients' treatment phase, surgery type, and physical function can improve shoulder function, body composition, and insulin resistance. These findings provide guidance for the development of effective exercise programs for patients with breast cancer post-operatively.
Review
Biochemistry & Molecular Biology
Erika Melendez-Oliva, Oliver Martinez-Pozas, Juan Nicolas Cuenca-Zaldivar, Jorge Hugo Villafane, Laura Jimenez-Ortega, Eleuterio A. Sanchez-Romero
Summary: This systematic review and meta-analysis examines the impact of pulmonary rehabilitation on subacute and long COVID-19 patients, evaluating improvements in dyspnea, physical function, quality of life, psychological state, and fatigue. The study included 34 studies involving 1970 patients and found moderate to large effects on dyspnea, physical function, quality of life, and depressive symptoms. However, caution should be taken due to the high risk of bias in the included studies.
Review
Rehabilitation
Kate Gamble, April Chiu, Casey Peiris
Summary: This study systematically reviewed the impact of core stability exercises in addition to usual care physiotherapy on patient outcomes after stroke. The findings suggest that incorporating core stability exercises may lead to improved trunk control, dynamic balance, and walking speed in individuals with acute and chronic stroke.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Rehabilitation
Christopher E. Henderson, Megan Fahey, Gabrielle Brazg, Jennifer L. Moore, T. George Hornby
Summary: This cohort investigation identifies the primary predictors of discharge walking function for nonambulatory poststroke patients undergoing high-intensity training during inpatient rehabilitation. The results indicate that steps per day, baseline Berg Balance Scale (BBS), and paretic leg strength are the primary predictors of walking outcomes.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Cardiac & Cardiovascular Systems
Rochelle Rocha Costa, Alexandra Ferreira Vieira, Leandro Coconcelli, Alex de Oliveira Fagundes, Adriana Cristine Koch Buttelli, Laura Frances Pereira, Ricardo Stein, Luiz Fernando Martins Kruel
Summary: This study examined the impact of simvastatin on lipid adaptations in elderly women with dyslipidemia undergoing water-based aerobics and resistance training. The results showed that participants on medication experienced greater decreases in total cholesterol, LDL, and TC/HDL ratio, with significant reductions observed in the resistance training group.
ARQUIVOS BRASILEIROS DE CARDIOLOGIA
(2021)
Review
Cardiac & Cardiovascular Systems
Filipe Ferrari, Rafael S. Scheffel, Vitor M. Martins, Raul D. Santos, Ricardo Stein
Summary: Type 2 diabetes is associated with high cardiovascular risk, and randomized controlled trials have shown the effectiveness of GLP-1 receptor agonists in reducing atherosclerotic cardiovascular events in patients with diabetes at high cardiovascular risk.
AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS
(2022)
Letter
Cardiac & Cardiovascular Systems
Alexandra C. G. B. Lima, Magno F. Formiga, Luiz T. Giollo, Marianne L. da Silva, Vinicius Z. M. da Silva, Maria E. B. Otto, Gaspar R. Chiappa, Gerson Cipriano
JOURNAL OF CARDIOVASCULAR MEDICINE
(2022)
Article
Environmental Sciences
Amanda Vale-Lira, Natalia Turri-Silva, Kenneth Verboven, Joao Luiz Quagliotti Durigan, Alexandra Correa G. B. de Lima, Martim Bottaro, Gaspar R. Chiappa, Dominique Hansen, Gerson Cipriano Jr
Summary: Exercise intolerance is a common issue in heart failure patients, and it is associated with muscle weakness. This study aimed to compare the microcirculatory and muscle characteristics between heart failure patients with HFpEF and HFrEF phenotypes. The researchers found that HFpEF patients showed more pronounced impairments in local microcirculatory dynamics during muscle strength exercise, combined with muscle-skeletal abnormalities detected via ultrasound imaging. These findings may help explain the exercise intolerance observed in HFpEF patients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Ricardo Stein, Mauricio Milani, Ana Abreu
ARQUIVOS BRASILEIROS DE CARDIOLOGIA
(2022)
Review
Physiology
William R. Pedon, Francisco V. Lima, Gerson Cipriano, Weder A. da Silva, Marcos V. S. Fernandes, Natalia S. Gomes, Adriana M. G. Chiappa, Rafael Pena de Sousa, Maria Eduarda Pereira da Silva, Gaspar R. Chiappa
Summary: This study summarizes the existing evidence on the acute response of low-load resistance exercise with blood flow restriction on hemodynamic parameters. The results indicate that low-load resistance exercise with blood flow restriction has similar effects on all hemodynamic parameters compared to conventional resistance exercise. Younger individuals show slightly higher chronotropic responses compared to older individuals.
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING
(2022)
Letter
Cardiac & Cardiovascular Systems
Marcos V. S. Fernandes, Paulo de Tarso Muller, Mariah Castilho dos Santos, Weder Alves da Silva, Adriana M. Guntzel Chiappa, Gaspar R. Chiappa
JOURNAL OF CARDIOVASCULAR MEDICINE
(2022)
Letter
Cardiac & Cardiovascular Systems
Filipe Ferrari, Anderson Donelli da Silveira, Ricardo Stein
ARQUIVOS BRASILEIROS DE CARDIOLOGIA
(2023)
Article
Cardiac & Cardiovascular Systems
Mauricio Milani, Juliana Goulart Prata Oliveira Milani, Graziella Franca Bernardelli Cipriano, Lawrence Patrick Cahalin, Ricardo Stein, Gerson Cipriano Jr
Summary: A study on post-COVID-19 patients with different illness severities found that peripheral muscle fatigue was the main cause of exercise intolerance. This suggests that comprehensive rehabilitation programs, aerobic exercise, and muscle training should be emphasized in the treatment.
ARQUIVOS BRASILEIROS DE CARDIOLOGIA
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Henrique Iahnke Garbin, Rafael Correa Caceres, Anderson Donelli da Silveira
EUROPEAN HEART JOURNAL-CASE REPORTS
(2023)
Review
Cardiac & Cardiovascular Systems
Ricardo Stein, Filipe Ferrari, Thais M. A. Beuren, Anderson D. D. da Silveira, Luciana Sacilotto
Summary: This review summarizes and discusses the primary causes of sudden cardiac death (SCD) in young athletes. SCD in young athletes is a dramatic event, and exercise can sometimes trigger it. Different cardiac conditions, both structural and nonstructural, can cause SCD. Routine cardiovascular screening methods may fail to detect nonstructural genetic cardiac diseases, and genetic testing can help identify individuals at risk.
CURRENT TREATMENT OPTIONS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Gustavo N. Araujo, Guilherme P. Machado, Marcia Moura, Anderson D. Silveira, Luiz Carlos Bergoli, Felipe Costa Fuchs, Sandro Cadaval Goncalves, Rodrigo Vugman Wainstein, Pedro A. Lemos, Alexandre S. Quadros, Marco V. Wainstein
Summary: This study compared the effectiveness of an ultrathin strut, sirolimus-eluting stent (Inspiron) with other third-generation drug-eluting stents (DES) in ST-elevation myocardial infarction (STEMI) patients. The results showed no significant differences in the rates of target vessel revascularization, stent thrombosis, mortality, and major cardiovascular outcomes between the two groups after a median follow-up of 17 months. Therefore, this study confirmed the safety and effectiveness of Inspiron in real-world clinical practice.
ARQUIVOS BRASILEIROS DE CARDIOLOGIA
(2023)
Review
Medicine, General & Internal
Filipe Ferrari, Vitor Magnus Martins, Flavio Danni Fuchs, Ricardo Stein
Summary: Investigations into the association between RAAS inhibitors and unfavorable prognosis in COVID-19 may be biased by underlying cardiovascular diseases. With the increase in global COVID-19 cases, it is now possible to conduct more in-depth investigations in larger cohorts.
Article
Medicine, General & Internal
Filipe Ferrari, Vitor M. Martins, Marcelo Teixeira, Raul D. Santos, Ricardo Stein
Summary: COVID-19 poses increased risks for individuals with underlying chronic diseases, potentially leading to complications such as hypercoagulability and inflammation. Ongoing research is exploring the effectiveness of traditional anticoagulation therapy and medications in addressing these complications.