G-protein coupled receptor 40 agonists as novel therapeutics for type 2 diabetes

Gemigliptin, a novel dipeptidyl peptidase 4 inhibitor: first new anti-diabetic drug in the history of Korean pharmaceutical industry

(2013) Sung-Ho Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

A novel therapeutic target, GPR43; Where it stands in drug discovery

(2012) Sunhong Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Dose-Ranging Effects of Canagliflozin, a Sodium-Glucose Cotransporter 2 Inhibitor, as Add-On to Metformin in Subjects With Type 2 Diabetes

(2012) J. Rosenstock et al.   DIABETES CARE

Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise

(2012) K. Stenlöf et al.   DIABETES OBESITY & METABOLISM

Optimization of (2,3-Dihydro-1-benzofuran-3-yl)acetic Acids: Discovery of a Non-Free Fatty Acid-Like, Highly Bioavailable G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonist as a Glucose-Dependent Insulinotropic Agent

(2012) Nobuyuki Negoro et al.   JOURNAL OF MEDICINAL CHEMISTRY

TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial

(2012) Charles F Burant et al.   LANCET

A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents

(2012) Jian Luo et al.   PLoS One

The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity

(2011) Da Young Oh et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

GPR40-induced insulin secretion by the novel agonist TAK-875: first clinical findings in patients with type 2 diabetes

(2011) T. Araki et al.   DIABETES OBESITY & METABOLISM

Review: Hydroxyoctadecadienoic acids: novel regulators of macrophage differentiation and atherogenesis

(2010) Venkat Vangaveti et al.   Therapeutic Advances in Endocrinology and Metabolism

G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell

(2009) Noel G. Morgan et al.   BIOCHEMICAL PHARMACOLOGY

Overexpression of GPR40 in Pancreatic  -Cells Augments Glucose-Stimulated Insulin Secretion and Improves Glucose Tolerance in Normal and Diabetic Mice

(2009) K. Nagasumi et al.   DIABETES

Fatty Acid Binding Receptors and Their Physiological Role in Type 2 Diabetes

(2008) Gayathri Swaminath   ARCHIV DER PHARMAZIE

Selective Small-Molecule Agonists of G Protein-Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice

(2008) C. P. Tan et al.   DIABETES