期刊
ARCHIVES OF PHARMACAL RESEARCH
卷 33, 期 10, 页码 1467-1473出版社
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-010-1001-z
关键词
Histone modification; Non-coding RNA; Stem cell; Neuron; Glia
资金
- Ministry of Education, Science and Technology [20100340, 2009-0089242]
- Seoul R BD program [20090656]
How a cell fate is determined and how tremendously diverse cells are generated during development are interesting and intriguing questions to be solved before using the stem cells for therapeutic purpose. Recently, it has been suggested that epigenetic control by the histone modifying enzymes and non-coding RNAs play important roles in guiding stem cells to differentiate into neurons or glia. In this review, we discuss the recent outcomes and advances in understanding the histone modifying enzymes and non-coding RNAs during neural cell-type specification of stem cells.
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