Article
Pharmacology & Pharmacy
Linlin Jiang, Baochang Zhou, Xiaoqin Wang, Yaqiong Bi, Wenfang Guo, Jianhua Wang, Ruyu Yao, Minhui Li
Summary: Cistanche deserticola Ma, a medicinal plant mainly found in the Alxa region of northwest China, has faced issues of overexploitation and quality deterioration due to increasing demand. Different types of value chains were found to impact the quality and stakeholders of Cistanches Herba, with quality assessment conducted using DNA barcoding and chemical analysis. Geographical suitability and vertical integration were identified as factors influencing the quality and sustainable production of Cistanches Herba.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Microbiology
Liliya Horbal, Marc Stierhof, Anja Palusczak, Nikolas Eckert, Josef Zapp, Andriy Luzhetskyy
Summary: Targeted genome mining is used to prioritize biosynthetic gene clusters, with this study identifying two different types containing capreomycidine biosynthesis genes and arginine hydroxylase gene respectively. Analysis of the flk cluster from Streptomyces albus led to the discovery of a cyclic peptide containing a rare D-capreomycidine moiety for the first time.
Article
Microbiology
Soohyun Um, Jaeyoun Lee, Seung Hyun Kim
Summary: This study focused on the endophytes of Maesa japonica and their interaction with the host plant at the metabolite level. Among the isolated endophytes, Streptomyces olivaceus JB1 was investigated for its antibacterial activities. Spectroscopic techniques confirmed the production of lobophorin analogs by JB1, and both reported and unreported analogs were detected. The presence of lobophorin A in the dried residues of M. japonica suggests that JB1 resides in the host and accumulates its secondary metabolites through interaction with the plant. Antimicrobial activity tests supported the mutualistic relationship between the host plant and the microbe. Additionally, lobophorin-producing Streptomyces spp. were also isolated from marine environments, and a saline water stress tolerance test showed that JB1 does not accelerate its growth in a saline medium.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Chemistry, Medicinal
Si -Si Liu, Rong Huang, Shou-Peng Zhang, Tang-Chang Xu, Kun Hu, Shao-Hua Wu
Summary: Two new nucleoside derivatives, kipukasins O (1) and P (2), one new cyclohexenone derivative, arthropsadiol D (5), and one new natural product, (+)-2,5-dimethyl-3(2H)-benzofuranone (6), were isolated from the culture broth of the endophytic fungus Aspergillus polyporicola R2. The absolute configuration of compound 5 was determined and the antimicrobial activities of these compounds were evaluated.
Article
Chemistry, Multidisciplinary
Mengmeng Lan, Tongxu Cui, Kaichun Xia, Guodong Cui, Yiwen Chu, Peng Fu, Weiming Zhu
Summary: (+/-)-Pyriindolin with a rare molecular backbone was isolated from Streptomyces albolongus EA12432. Its constitution and relative configuration were determined by spectroscopic analyses and probability analysis, while the absolute configurations of optically pure samples were identified by HPLC separation and ECD calculations. The compounds exhibited moderate cytotoxicity.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Youjuan Zhu, Yichao Kong, Yu Hong, Ling Zhang, Simin Li, Shurong Hou, Xiabin Chen, Tian Xie, Yang Hu, Xiachang Wang
Summary: Three new polyketide dimers named huoshanmycins A-C were isolated from a plant endophytic Streptomyces sp. The compounds exhibited unique structures and showed moderate cytotoxicity against human leukemia cells.
FRONTIERS IN CHEMISTRY
(2022)
Article
Microbiology
Pawina Kanchanasin, Paranee Sripreechasak, Chanwit Suriyachadkun, Kanokorn Rueangsawang, Somboon Tanasupawat, Wongsakorn Phongsopitanun
Summary: Two endophytic actinobacteria were isolated from the roots of Barleria lupulina collected in Thailand, and identified as novel species of the genus Streptomyces, namely Streptomyces cylindrosporus and Streptomyces spinosisporus. They exhibited distinct morphological characteristics, chemotaxonomic properties, and 16S rRNA gene sequences from closely related type strains. Comparative genome analysis confirmed their differentiation at the species level. These findings contribute to the understanding and classification of Streptomyces species.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2023)
Article
Chemistry, Applied
Jian-Bing Tan, Wei-Wei Peng, Mei-Fang Li, Feng-Hua Kang, Yu-Ting Zheng, Li Xu, Si-Yu Qin, Yuan-Tao Huang, Zhen-Xing Zou
Summary: One new cyclopeptide, one new 2-pyridone derivative, and one new natural indole derivative, along with six known compounds, were isolated from the endophytic fungus Fusarium proliferatum T2-10. The structures of the new compounds were identified using spectral methods and the absolute configuration of compound 1 was determined using the Marfey-MS method. In addition, compound 2 exhibited significant cytotoxic and moderate antibacterial activities.
NATURAL PRODUCT RESEARCH
(2023)
Article
Plant Sciences
Lidan Cao, Yan Gao, Jinlan Yu, Shuqi Niu, Jiarui Zeng, Qingqing Yao, Xiang Wang, Zhigang Bu, Ting Xu, Xuanming Liu, Yonghua Zhu
Summary: The endophytic actinobacteria OsiSh-2 can enhance the resilience of host plants against iron deficiency stress by modulating iron acquisition and translocation, ultimately leading to improved plant fitness.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Sapna Devi, Manish Sharma, Rajesh Kumari Manhas
Summary: This study aimed to explore the antimicrobial activity of Streptomyces sp. SP5 against drug-resistant bacteria and fungal phytopathogens. A compound called plicacetin was isolated and identified from the extract of Streptomyces sp. SP5, and it exhibited broad-spectrum antimicrobial activity against various drug-resistant bacteria and fungi.
SCIENTIFIC REPORTS
(2023)
Article
Microbiology
Zhilong He, Kunpeng Cui, Rui Wang, Ting Xu, Zhen Zhang, Xiangnan Wang, Yongzhong Chen, Yonghua Zhu
Summary: This study found that the endophyte Streptomyces albidoflavus OsiLf-2 can alleviate the negative effect of drought stress on Camellia oleifera. It improves the quality of seeds, oil, and fruit by affecting the microbial community structure in the rhizosphere soil, reducing root cell water loss, and synthesizing osmoregulatory substances. OsiLf-2 also induces the host to resist drought stress by increasing peroxidase activity and synthesizing antioxidants. This research provides theoretical and technical support for future application of endophytes to enhance drought resistance, yield, and quality of C. oleifera.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Chemistry, Applied
Paulina Bekiesch, Martina Oberhofer, Christina Sykora, Ernst Urban, Sergey B. Zotchev
Summary: The study identified new antibacterial compounds from the culture broth of endophytic Streptomyces sp. AB100, showing its potential in drug synthesis. Only compounds with specific structures exhibited weak antibacterial activity against Gram-positive bacteria.
NATURAL PRODUCT RESEARCH
(2021)
Article
Microbiology
Wongsakorn Phongsopitanun, Pawina Kanchanasin, Paranee Sripreechasak, Kanokorn Rueangsawang, Anan Athipornchai, Khomsan Supong, Pattama Pittayakhajonwut, Somboon Tanasupawat
Summary: In this study, endophytic actinobacterial strain 3R004T was isolated from the root of Justicia subcoriacea collected in Thailand. Through a polyphasic approach, it was identified as a member of the genus Streptomyces, producing actinomycin D as a major secondary metabolite. The taxonomic position and characteristics of strain 3R004(T) were determined using morphological, chemical, and phylogenomic analyses.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Kunpeng Cui, Ting Xu, Jiawei Chen, Haiyu Yang, Xuanming Liu, Rui Zhuo, Yinghe Peng, Wei Tang, Rui Wang, Longsheng Chen, Xuan Zhang, Zhen Zhang, Zhilong He, Xiangnan Wang, Caixia Liu, Yongzhong Chen, Yonghua Zhu
Summary: In this study, a Streptomyces sp. CoT10 was screened and identified from Camellia oleifera endophytes, and it exhibited high phosphorus mobilization capacity and siderophore production. CoT10 inoculation improved soil phosphorus content, plant growth, and microbial diversity in C. oleifera rhizosphere soil, indicating its potential application in iron-rich soil for sustainable plant-related industries development.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Microbiology
Onuma Kaewkla, Chanwit Suriyachadkun, Christopher Milton Mathew Franco
Summary: A new endophytic actinobacterium strain PIP175(T) was isolated from the root sample of a native apricot tree in Australia. It belongs to the genus Streptomyces and shows high similarity to Streptomyces aculeolatus DSM 41644(T). Strain PIP175(T) exhibits potential for antibiotic production and plant growth promotion.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2023)
