Article
Biotechnology & Applied Microbiology
Paul Mcmullin, Darian Emmett, Andrew Gibbons, Kelly Clingo, Preston Higbee, Andrew Sykes, David T. Fullwood, Ulrike H. Mitchell, Anton E. Bowden
Summary: This study utilized an optical motion capture system and a new marker set to non-invasively measure the dynamic, 3D in vivo segmental kinematics of the lower spine in a laboratory setting. The results were consistent with previous studies and identified motion coupling paradigms in the lumbar spinal segments.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Orthopedics
Ofir Uri, Liad Alfandari, Yoram Folman, Amit Keren, William Smith, Inbar Paz, Eyal Behrbalk
Summary: This study compared the incidence of acute disc herniation following mini-open and minimally invasive decompression of lumbar spinal stenosis. The results showed that the incidence of postoperative disc herniation was significantly lower in the minimally invasive group compared to the mini-open group.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Alexander Breen, Diana De Carvalho, Martha Funabashi, Greg Kawchuk, Isabelle Page, Arnold Y. L. Wong, Alan Breen
Summary: Quantitative fluoroscopy (QF) can reliably measure continuous lumbar intervertebral rotational displacement patterns, providing a basis for assessing patients with suspected lumbar spine motion disorders. A reference database of spinal displacement patterns during lumbar intersegmental flexion and return motion is presented, with significant differences between asymptomatic individuals and patients with chronic low back pain.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Clinical Neurology
Jose A. Canseco, Brian A. Karamian, Mark J. Lambrechts, Tariq Z. Issa, William Conaway, Paul D. Minetos, Daniel Bowles, Tyler Alexander, Matthew Sherman, Gregory D. Schroeder, Alan S. Hilibrand, Alexander R. Vaccaro, Christopher K. Kepler
Summary: To reduce healthcare costs, some surgeons are transitioning lumbar decompression patients to outpatient procedure centers. A risk stratification calculator based on machine learning algorithms was developed to improve the surgeon's ability to predict whether a patient undergoing lumbar decompression will meet inpatient or outpatient criteria.
Article
Medicine, General & Internal
Morsi Khashan, Dror Ofir, Uri Hochberg, Haggai Schermann, Gilad J. Regev, Zvi Lidar, Khalil Salame
Summary: This study compared the effect of smoking on the outcome of spinal decompression surgery. Retrospective analysis of 188 cases of MIS lumbar decompression surgery found no significant difference in perioperative complications and revision surgery rates between smokers and non-smokers, but smoking may delay the improvement of leg pain and disability.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Environmental Sciences
Tomasz Kuligowski
Summary: This study aimed to analyze the prevalence of lumbar segmental instability (LSI) in young patients with different types of lumbar disc herniation (LDH). The results showed that individuals with more severe disc damage were more likely to have LSI. Additionally, females were more prone to this pathology. The different types of LDH did not significantly affect the prevalence of LSI in young individuals.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Surgery
Xiao Xiao, Gaoyang Chen, Song Wang, Junliang Liu, Erhu Lin, Ke Chen, Yucheng Xiang, Ke Zhan, Congcong Liu, Zhengbin Yuan, Minjie Yang, Shuyuan Zhong, Wanxin Zhen, Dazhi Yang, Songlin Peng
Summary: The efficacy of hybrid surgery and traditional surgery was compared in patients with multi-segmental lumbar spinal stenosis. It was found that the hybrid surgery preserved more motion range and had no early complications in a one-year follow-up.
FRONTIERS IN SURGERY
(2022)
Article
Clinical Neurology
Qingshuang Zhou, Xu Sun, Yong Qiu, Zezhang Zhu, Liang Xu, Xiaojiang Pu, Bo Yang, Sinian Wang
Summary: This study compared different radiographic positions and the use of CT scout view, 3D reconstruction, and MR image to evaluate olisthesis and segmental instability. The results showed that lateral and supine positions had better reduction of olisthesis, while flexion radiographs combined with supine or decubitus radiographs revealed greater mobility.
EUROPEAN SPINE JOURNAL
(2022)
Article
Orthopedics
Dorothea Daentzer, Elina Venjakob, Jessica Schulz, Thorsten Schulze, Michael Schwarze
Summary: The aim of this prospective study was to evaluate the clinical outcome in patients who underwent microsurgical decompression in the lumbar spine and analyze intervertebral movement using upright, kinetic-positional MRI over a 12-month period and correlate the clinical and imaging data.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Neurosciences
Colin D. McKinnon, Jack P. Callaghan
Summary: This study investigated the relationship between lumbar segmental axial twist and external thoracopelvic twist using ultrasound and motion capture techniques. The findings suggest a mathematical link between internal and external axial twist motion, with most motion occurring at the L2-L3 and L5-S1 intervertebral joints. The distribution of motion across the lumbar spine indicates that using L4-L5 to represent lumbar spine motion may not be suitable for axial twist modeling approaches.
HUMAN MOVEMENT SCIENCE
(2021)
Article
Orthopedics
Laura Marie-Hardy, Marc Khalife, Peter Upex, Guillaume Riouallon, Stephane Wolff
Summary: The goal of this study was to precisely measure the decompression of central stenosis by unilateral MIS approaches using MRI. The analysis of 42 patients showed that the dural sac cross-sectional area and anteroposterior diameter increased significantly postoperatively, indicating a successful decompression.
ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH
(2023)
Article
Clinical Neurology
Chen Zhao, Liehua Liu, Lei Luo, Pei Li, Yiyang Wang, Lichuan Liang, Xueping Wen, Dianming Jiang, Qiang Zhou
Summary: The study compared the clinical efficacy of decompression of the spinal canal with or without discectomy on the treatment of lumbar degenerative diseases using Dynesys dynamic fixation. Results showed that decompression without discectomy may lead to better preservation of intervertebral height and range of motion, and reduce disc degeneration.
PAIN RESEARCH & MANAGEMENT
(2021)
Review
Clinical Neurology
Signe F. Elmose, Gustav O. Andersen, Leah Yacat Carreon, Freyr G. Sigmundsson, Mikkel O. Andersen
Summary: This systematic review collected and grouped definitions of segmental instability in surgical studies of patients with lumbar spinal stenosis and/or lumbar degenerative spondylolisthesis. The study reported the frequencies of these definitions, compared imaging measurement thresholds for instability in patients with those reported in biomechanical studies and studies of spine healthy individuals, and included a reliability study. The results showed that segmental instability can radiologically be defined as > 3 mm dynamic sagittal translation in degenerative lumbar spine.
GLOBAL SPINE JOURNAL
(2023)
Review
Orthopedics
Jennifer Fayad, Peter Endre Eltes, Aron Lazary, Luca Cristofolini, Rita Stagni
Summary: The literature offers various stereophotogrammetric protocols for quantifying the multi-segmental motion of the thoracolumbar spine, but a standard guideline is lacking. From a clinical perspective, the application of these approaches is still limited. Further research is needed to define a precise motion analysis protocol and determine its clinical relevance.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Biotechnology & Applied Microbiology
Seyed Javad Mousavi, Andrew C. Lynch, Brett T. Allaire, Andrew P. White, Dennis E. Anderson
Summary: The study found that patients with symptomatic lumbar spinal stenosis exhibit slight changes in spine posture and pelvic tilt during standing and walking, but these changes are not significantly affected by symptoms. However, there was an average 7% increase in lumbar spine loading during symptomatic walking compared to asymptomatic walking. This suggests that provocation of symptoms in patients with lumbar spinal stenosis does not greatly alter their normal gait kinematics.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Otorhinolaryngology
C. Offergeld, M. Ketterer, M. Neudert, F. Hassepass, N. Weerda, B. Richter, L. Traser, C. Becker, N. Deeg, A. Knopf, T. Wesarg, A-K. Rauch, T. Jakob, F. Ferver, F. Lang, V. Vielsmeier, S. Hackenberg, M. Diensthuber, M. Praetorius, B. Hofauer, N. Mansour, S. Kuhn, T. Hildenbrand
Summary: The study revealed successful examples of transformation of classroom teaching to an exclusively virtual summer semester 2020 within university ENT clinics, but critical ratings from assistant professors and medical directors dominated regarding the current teaching situation. Urgent time-critical strategic advancement is needed.
Article
Otorhinolaryngology
Friederike Lang, Ben Everad, Andreas Knopf, Sebastian Kuhn, Christian Offergeld
Summary: This study evaluated the structure, functions, and usage of the ENT Learning Program developed by the University Hospital of Freiburg. Findings from questionnaire surveys and website visit data indicated that students widely used the program and perceived it as beneficial for exam preparation and motivation. The controlled study showed significantly better test outcomes in students who used the program.
LARYNGO-RHINO-OTOLOGIE
(2021)
Article
Surgery
Sebastian Kuhn, Florentine Huettl, Kim Deutsch, Elisa Kirchgaessner, Tobias Huber, Werner Kneist
Summary: This study evaluated a newly developed learning/teaching concept for the digital transformation of medicine, focusing on surgical teaching, through a series of courses involving virtual reality, augmented reality, and robotics, combined with semi-structured interviews and standardized evaluation questionnaires. Students considered expert discussion as an essential part of the course concept, and viewed it as a horizon-widening learning experience with high practical relevance. Quantitative student evaluation showed a positive development in knowledge, skills, and attitude.
ZENTRALBLATT FUR CHIRURGIE
(2021)
Article
Emergency Medicine
Iris Reiner, Manfred E. Beutel, Philipp Winter, Pol M. Rommens, Sebastian Kuhn
Summary: High distress and being involved in a car accident were identified as potential risk factors for the development of posttraumatic stress in trauma patients recruited from the resuscitation room.
SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE
(2021)
Article
Emergency Medicine
Julia Greenfield, Philipp Appelmann, Felix Wunderlich, Dorothea Mehler, Pol Maria Rommens, Sebastian Kuhn
Summary: The study assessed the feasibility of using retrograde tibial nailing with double rather than triple-distal locking for far distal tibia fractures. It was found that the use of double locking preserved a significant amount of stiffness while maintaining stability in the fracture site.
EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY
(2022)
Article
Psychiatry
Severin Hennemann, Sebastian Kuhn, Michael Witthoeft, Stefanie M. Jungmann
Summary: This study tested the diagnostic performance of a widely available symptom checker in the context of formal diagnosis of mental disorders. The results showed that the tool could provide clinicians with a list of condition suggestions with moderate-to-good accuracy, but there were differences in diagnostic performance between disorder categories and low interrater reliability. Approximately 71% of participants preferred face-to-face diagnosis.
JMIR MENTAL HEALTH
(2022)
Article
Education & Educational Research
Elizabete Neutel, Sebastian Kuhn, Peter Driscoll, Carl Gwinnutt, Zelia Moreira, Ana Veloso, Maria Conceicao Manso, Antonio Carneiro
Summary: This study aimed to assess the self-perceived impact of the European Trauma Course (ETC) on Reanima trainees' behavior and organizational change. A questionnaire based on Holton's evaluation model was used to evaluate the candidates' perceptions. The results showed that participation in the ETC led to behavioral changes in trauma care and had a significant impact on individuals' attitudes.
BMC MEDICAL EDUCATION
(2023)
Article
Health Care Sciences & Services
Igor Bibi, Daniel Schaffert, Mara Blauth, Christian Lull, Jan Alwin von Ahnen, Georg Gross, Wanja Alexander Weigandt, Johannes Knitza, Sebastian Kuhn, Johannes Benecke, Jan Leipe, Astrid Schmieder, Victor Olsavszky
Summary: This study used AutoML to analyze clinical research data of patients with chronic eczema or psoriasis who used a smartphone monitoring app. The study found correlations between important features and outcomes, highlighting the potential of smartphone and AutoML techniques in improving chronic disease management and patient care.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Health Care Sciences & Services
Lena Rettinger, Sebastian Kuhn
Summary: This study aimed to identify and map the perceived barriers to the use of video call-based telehealth interventions among allied health professionals and nurses. After conducting 56 studies in various countries, the barriers were categorized into 8 main categories and 23 subcategories. Common barriers included technology issues, practice issues, patient issues, environmental issues, attributions, interpersonal issues, policies and regulations, and administration issues.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Health Care Sciences & Services
Sebastian Griewing, Niklas Gremke, Uwe Wagner, Michael Lingenfelder, Sebastian Kuhn, Jelena Boekhoff
Summary: The recent availability of large language models (LLMs) has sparked interest in using artificial intelligence for medical purposes. This study compares the treatment recommendations of the LLM ChatGPT 3.5 with those of a tumor board for breast cancer. The results show that while there is some agreement between the LLM and the tumor board, there are also significant discrepancies, raising concerns about the reliability of publicly available LLMs for medical decision-making.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Rheumatology
Sophie von Rohr, Johannes Knitza, Manuel Grahammer, Marc Schmalzing, Sebastian Kuhn, Georg Schett, Andreas Ramming, Hannah Labinsky
Summary: The study aimed to investigate the use of student-led clinics and electronic patient-reported outcomes (ePROs) for the diagnosis and treatment of patients with axial spondyloarthritis (axSpA). The results showed that student-led clinics significantly accelerated patient appointments and NSAID therapy start, and completed the diagnostic workup for all patients. The electronic and paper-administered BASDAI questionnaires showed good correlation. Both student-led clinics and ePRO monitoring were well accepted by patients.
RHEUMATOLOGY INTERNATIONAL
(2023)
Article
Education, Scientific Disciplines
Christoph Raphael Buhr, Harry Smith, Tilman Huppertz, Katharina Bahr-Hamm, Christoph Matthias, Andrew Blaikie, Tom Kelsey, Sebastian Kuhn, Jonas Eckrich
Summary: This study evaluated the performance of ChatGPT in answering clinical case-based questions in otorhinolaryngology (ORL) and compared it with the answers from ORL consultants. The study found that although ChatGPT provided longer answers, its medical adequacy and conciseness were significantly lower compared to the answers from ORL consultants.
JMIR MEDICAL EDUCATION
(2023)
Article
Rheumatology
Labinsky Hannah, Rohr von Sophie, Raimondo Maria Gabriella, Bohr Daniela, Morf Harriet, Horstmann Britta, Seese Felix, Proft Fabian, Muehlensiepen Felix, Boy Katharina, Kuhn Sebastian, Schmalzing Marc, Vuillerme Nicolas, Schett Georg, Ramming Andreas, Knitza Johannes
Summary: Patients with suspected axSpA can benefit from a stepwise asynchronous telemedicine-based diagnostic approach, which can potentially reduce the diagnostic delay and improve accuracy. Sufficient information, especially imaging results, is essential for correct diagnosis.
RHEUMATOLOGY INTERNATIONAL
(2023)
Article
Rheumatology
Dmytro Fedkov, Andrea Berghofen, Christel Weiss, Christine Peine, Felix Lang, Johannes Knitza, Sebastian Kuhn, Bernhard K. Kraemer, Jan Leipe
Summary: This study evaluated the efficacy and safety of a digital health application in patients with inflammatory arthritis. The results showed that using a personalized disease management program based on digital health significantly improved patient-reported outcomes and disease activity.
RHEUMATOLOGY INTERNATIONAL
(2022)
Article
Rheumatology
Markus Graef, Johannes Knitza, Jan Leipe, Martin Krusche, Martin Welcker, Sebastian Kuhn, Johanna Mucke, Axel J. Hueber, Johannes Hornig, Philipp Klemm, Stefan Kleinert, Peer Aries, Nicolas Vuillerme, David Simon, Arnd Kleyer, Georg Schett, Johanna Callhoff
Summary: This study compared the accuracy of an AI-based symptom checker (Ada) to physicians in diagnosing inflammatory rheumatic diseases (IRD). The study found that Ada had higher diagnostic accuracy compared to physicians when considering basic health and symptom-related medical history. These results highlight the potential of using symptom checkers early in the patient journey and the importance of complete patient information for accurate diagnosis.
RHEUMATOLOGY INTERNATIONAL
(2022)