Article
Dentistry, Oral Surgery & Medicine
Danuta Ostalska-Nowicka, Elzbieta Paszynska, Monika Dmitrzak-Weglarz, Anna Neyman-Bartkowiak, Alina Rabiega, Jacek Zachwieja, Michal Nowicki
Summary: The study found that tooth decay may be an important factor in triggering hypertension in children and adolescents, especially when other secondary causes of arterial hypertension have been excluded. Uric acid concentration, salivary cortisol, and alpha-amylase levels were associated with hypertension, but only tooth decay was significantly associated with hypertension in both children and adolescents.
Article
Health Care Sciences & Services
Lude Lin, Wanting Chen, Dejun Zhong, Xiayuan Cai, Jieyi Chen, Fang Huang
Summary: This survey examined the prevalence of malocclusion and its associated factors in 3- to 5-year-old children in Huizhou, China. The study found that over half of the children had malocclusion, with deep overbite being the most common issue. Lip-biting habits were associated with a higher prevalence of deep overbite, while digit-sucking habits and dental caries in anterior maxillary teeth were associated with a lower prevalence of deep overbite.
Article
Dentistry, Oral Surgery & Medicine
Basak Gunay, Mustafa Sarp Kaya, Ilker Tolga Ozgen, Eray Metin Guler, Abdurrahim Kocyigit
Summary: This study evaluated the relationship between pain inflammation due to dental caries and growth parameters, sleep disturbances, and oral health-related quality of life (OHRQoL). The results showed that children's growth parameters, sleep disturbances, and OHRQoL improved after the elimination of pain and inflammation.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Microbiology
Weihua Shi, Jing Tian, He Xu, Man Qin
Summary: Epidemiological studies have found a correlation between caries in deciduous molars and permanent molars. This study investigated the association between caries subtypes in deciduous molars and first permanent molars, as well as the microbiota involved in different subtypes. The results suggest that classification of deciduous molar caries based on the microbiota could predict the risk of caries in adjacent first permanent molars.
Article
Dentistry, Oral Surgery & Medicine
Angela Dalla Nora, Luana Severo Alves, Nathalia Costa de Castro, Marisa Maltz, Julio Eduardo do Amaral Zenkner
Summary: This study evaluated the radiographic features of inactive enamel caries lesions in permanent molars and found that lesions with radiolucency at baseline were more likely to progress over 4-5 years. The presence of radiolucency at baseline was a predictor of caries progression, indicating the importance of closer monitoring for such lesions. The use of bitewing radiographs can help identify surfaces/lesions more likely to progress and establish proper recall intervals for patient monitoring.
JOURNAL OF DENTISTRY
(2021)
Article
Biochemistry & Molecular Biology
Lei Xu, Zhifang Wu, Yuan Wang, Sa Wang, Chang Shu, Zhuhui Duan, Shuli Deng
Summary: This study aimed to identify the salivary microbiota in caries-free Chinese preschool children using high-throughput sequencing. The results showed a similar microbiota pattern between male and female subjects, with differences mainly attributed to the genus Neisseria. The most abundant genes in the salivary microbiota were related to amino acid transport and metabolism, providing basic information for understanding the oral microbiota in caries-free populations.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B
(2021)
Article
Dentistry, Oral Surgery & Medicine
Catarina Borges da Fonseca Cumerlato, Mariana Gonzalez Cademartori, Fernando Celso Barros, Andrea Homsi Damaso, Mariangela Freitas da Silveira, Pedro Curi Hallal, Flavio Fernando Demarco, Marcos Britto Correa
Summary: This study found that maternal depression trajectory from pregnancy to 24 months increased the risk of children developing dental caries at 48 months. Children from mothers with high depression trajectory had a higher risk of dental caries at 48 months compared to children from mothers with low depression trajectory.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
L. C. Diel, J. Abanto, J. L. Ferreira Antunes, J. C. Pettorossi Imparato, L. Franco Ramos, F. Guinot Jimeno, L. Butini Oliveira
Summary: The aim of this study was to assess parental preferences for dental caries treatment and its association with socio-demographic conditions and beliefs about the primary dentition. The results showed that a considerable proportion of parents prefer nonconservative dental treatments for their children. Older and more educated mothers were significantly associated with a preference for conservative interventions, and these preferences were also related to beliefs about the primary dentition.
EUROPEAN JOURNAL OF PAEDIATRIC DENTISTRY
(2022)
Article
Health Care Sciences & Services
Manarin Boonyawong, Prim Auychai, Duangporn Duangthip
Summary: This study found that dental caries is prevalent among Thai preschool children, and factors such as age, oral hygiene, and maternal education level are associated with the risk of dental caries.
Article
Medicine, General & Internal
Ulrich Schiffner
Summary: The dental caries burden in German children's deciduous dentition has decreased over the past decades. Children from different social classes and migration backgrounds have experienced similar reductions in caries.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Sheetal Manchanda, Pei Liu, Gillian Hiu Man Lee, Edward Chin Man Lo, Cynthia Kar Yung Yiu
Summary: The aim of this study was to evaluate the risk indicators associated with noncavitated and cavitated lesions in preschool children. The study found that poor oral hygiene is a risk indicator for the presence of noncavitated lesions in preschool children, while poor oral hygiene and poor parental oral health knowledge and attitude are associated with the presence of cavitated lesions.
INTERNATIONAL DENTAL JOURNAL
(2023)
Article
Nutrition & Dietetics
Karina Ferreira Rizzardi, Camila Lopes Crescente, Claudia Maria dos Santos Pereira Indiani, Carolina Steiner-Oliveira, Marines Nobre-dos-Santos, Thais Manzano Parisotto
Summary: This research report explores the relationship between obesity, anthropometric measurements, and early childhood caries (ECC) in young children. The study found that peripheral adiposity, as indicated by hip circumference, is associated with ECC. Therefore, hip circumference may be a valuable tool for understanding the connection between caries and obesity in early childhood.
FRONTIERS IN NUTRITION
(2022)
Article
Dentistry, Oral Surgery & Medicine
J. W. Li, R. M. Wyllie, P. A. Jensen
Summary: The study introduces a new ComRS competence system in Streptococcus sobrinus, which enables genetic transformation with synthetic XIP and reveals the mechanism of induced and suppressed competence. The research also identifies two strains of S. sobrinus that may be cheaters, one not responding to XIP and the other not producing XIP.
JOURNAL OF DENTAL RESEARCH
(2021)
Review
Endocrinology & Metabolism
G. Dipalma, A. D. Inchingolo, F. Inchingolo, I. A. Charitos, M. Di Cosola, A. P. Cazzolla
Summary: This paper discusses the biochemical interactions between teeth and the oral environment during the caries process, including physico-chemical reactions, theoretical basis for prevention and treatment, 'demineralization' and 'remineralization', the role of microbiota, as well as the mechanisms of carious lesion development, healing, and repair.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ivam Freire da Silva Junior, Francine Dos Santos Costa, Marcos Britto Correa, Fernando Celso Lopes Fernandes de Barros, Ina da Silva Dos Santos, Alicia Matijasevich, Flavio Fernando Demarco, Marina Sousa Azevedo
Summary: This study evaluated the validity of partial protocols in assessing the prevalence of developmental defects of enamel (DDE) in permanent teeth and found that partial protocols showed similar association strength compared to the full-mouth exam. They can be used to estimate the prevalence of DDE in epidemiological studies.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Andreia Alves Cardoso, Emerson Tavares de Sousa, Carolina Steiner-Oliveira, Marines Nobre-dos-Santos
Summary: This study investigated the effects of orthodontic appliance removal (OAR) combined with caries-preventive strategies and fluoride varnish treatments on salivary physicochemical properties, the activity of carbonic anhydrase VI (CA VIACT) and alpha-amylase (alpha-AML(ACT)), and the regression of active caries lesions (ACL). The results showed that this treatment significantly reduced the number of ACL, decreased the percentage of visible biofilm and sugar exposure, and increased salivary pH and alpha-AML(ACT) activity. However, salivary buffering capacity and CA VIACT activity remained stable throughout the follow-up.
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY
(2022)
Article
Oncology
Juliana Benine-Warlet, Alejandra Brenes-Alvarado, Carolina Steiner-Oliveira
Summary: The addition of potassium iodide (KI) to antimicrobial photodynamic therapy using methylene blue and red laser was found to further reduce the viability of Streptococcus mutans biofilm. There was no significant interaction between pre-irradiation time and irradiation.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2022)
Article
Microbiology
Maria Imaculada de Queiroz Rodrigues, Camila Carvalho de Oliveira Coelho, Fabricio Bitu Sousa, Lidiany Karla Azevedo Rodrigues Gerage, Mario Rogerio Lima Mota, Ana Paula Negreiros Nunes Alves
Summary: This study describes a new protocol for polymicrobial oral conventionalization in mice. By inoculating specific pathogen free animals with wild mouse microbiota, the researchers were able to achieve colonization of a microbiota similar to that of wild animals for up to 80 days. This technique proves to be effective, low-cost, and easily reproducible.
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Isabela Arague Catanoze, Bruno Guandalini Cunha, Gabriella Queiroz Costa, Emily Vivianne Freitas da Silva, Cristiane Duque, Aimee Maria Guiotti
Summary: The study aimed to evaluate the influence of different strains of probiotics and commercially available probiotic supplements on the growth of Candida albicans biofilm on acrylic resin denture base material in vitro. The results showed that several probiotics significantly decreased the number of C. albicans cells and altered the surface roughness of the specimens after exposure to biofilms.
JOURNAL OF PROSTHETIC DENTISTRY
(2022)
Article
Oncology
Esdras Gabriel Alves-Silva, Rodrigo Arruda-Vasconcelos, Lidiane Mendes Louzada, Adriana de-Jesus-Soares, Caio Cezar Randi Ferraz, Jose Flavio Affonso Almeida, Marina Angelica Marciano, Carolina Steiner-Oliveira, Marina Stella Bello-Silva, Hagay Shemesh, Brenda Paula Figueiredo de Almeida Gomes
Summary: This study aimed to investigate the effects of photodynamic therapy on pain control after endodontic treatment. The results showed that photodynamic therapy significantly reduced post-endodontic treatment pain, particularly in teeth with necrotic pulp and asymptomatic periapical lesions.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2022)
Article
Multidisciplinary Sciences
Camila Lopes Crescente, Emerson Tavares de Sousa, Aline Tavares Lima-Holanda, Carolina Steiner-Oliveira, Marines Nobre-dos-Santos
Summary: This study aimed to investigate the combined effect of biofilm accumulation and sucrose rinse on the bioavailability of calcium, phosphate, and fluoride in the saliva of children with early childhood caries (ECC). The results showed that the combined effect of biofilm accumulation and sucrose rinse altered the bioavailability of calcium and fluoride.
SCIENTIFIC REPORTS
(2022)
Review
Pediatrics
Cristiane Duque, Daniela Alvim Chrisostomo, Amanda Caselato Andolfatto Souza, Gabriela Pacheco de Almeida Braga, Vanessa Rodrigues dos Santos, Karina Sampaio Caiaffa, Jesse Augusto Pereira, Warlley Campos de Oliveira, Apoena de Aguiar Ribeiro, Thais Manzano Parisotto
Summary: Early childhood caries (ECC) is a common chronic disease in young children, characterized by atypical and fast progressive caries lesions. The severe form of ECC, known as S-ECC, can cause significant tooth damage and affect the child's quality of life. The development of ECC is driven by an imbalance between the oral microbiome and the host, mediated by high sugar consumption and poor oral hygiene. Understanding the microbiome in ECC is crucial for risk monitoring and the development of therapies to restore oral health.
CURRENT PEDIATRIC REVIEWS
(2023)
Article
Oncology
Alejandra Brenes-Alvarado, Jorge Soto-Montero, Felipe Fabricio Farias-da-Silva, Juliana Benine-Warlet, Andreza Ferraz Ribeiro, Francisco Carlos Groppo, Carolina Steiner-Oliveira
Summary: The study evaluated the efficacy of methylene blue (MB)-mediated antimicrobial photodynamic therapy doped with potassium iodide (KI) against oral microcosms biofilms cultured in dentin. Results showed that the addition of KI was effective in reducing oral microorganisms in the biofilms, but the effect varied among different treatment groups.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2022)
Article
Engineering, Biomedical
Gabriela Pacheco de Almeida Braga, Karina Sampaio Caiaffa, Jesse Augusto Pereira, Vanessa Rodrigues dos Santos, Amanda Caselato Andolfatto Souza, Lucas da Silva Ribeiro, Emerson Rodrigues Camargo, Anuradha Prakki, Cristiane Duque
Summary: This study evaluated the cytotoxicity and microbiological properties of PNVCL hydrogels containing flavonoids as intracanal medication for endodontic therapy. AMP showed effective antimicrobial activity against tested bacteria and PNVCL+AMP caused a significant decrease and disorganization of multi-species biofilms.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2022)
Article
Oncology
Esdras Gabriel Alves-Silva, Rodrigo Arruda-Vasconcelos, Lidiane Mendes Louzada, Adriana de-Jesus-Soares, Caio Cezar Randi Ferraz, Jose Flavio Affonso Almeida, Marina Angelica Marciano, Carolina Steiner-Oliveira, Joao Miguel Marques Santos, Brenda P. F. A. Gomes
Summary: This study evaluated the effectiveness of supplemental photodynamic therapy (aPDT) in improving bacterial removal and reducing the levels of lipopolysaccharide (LPS) and lipoteichoic acid (LTA) in root canals. The results showed that aPDT significantly decreased bacterial counts and levels of LPS and LTA.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2023)
Article
Dentistry, Oral Surgery & Medicine
I. B. Camatta, N. F. Peres, M. Z. D. Picolo, V. Cavalli, C. Steiner-Oliveira
Summary: This study evaluated the effect of salivary acquired pellicle (AP) on dentin darkening and caries arresting after using SDF + KI. The results showed that SDF and APSDF groups had no difference in color, while KISDF and APKISDF groups had significantly different colors compared to those without KI. SDF, APSDF, and APKISDF groups had less mineral loss and greater mineral recovery compared to C and KISDF groups. The presence of AP did not affect dentin color after SDF + KI, but played a protective role in modulating dentin mineral gain/loss. KI reduced dentin darkening and did not interfere with dentin de/remineralization process.
EUROPEAN ARCHIVES OF PAEDIATRIC DENTISTRY
(2023)
Article
Engineering, Biomedical
Gabriela Pacheco de Almeida Braga, Karina Sampaio Caiaffa, Rafaela Laruzo Rabelo, Vanessa Rodrigues dos Santos, Amanda Caselato Andolfatto Souza, Lucas da Silva Ribeiro, Emerson Rodrigues de Camargo, Anuradha Prakki, Cristiane Duque
Summary: This study aimed to evaluate the effects of flavonoids incorporated into PNVCL hydrogel on odontoblast-like cells. The results showed that the addition of flavonoids increased cell viability and mineralization markers. AMP and AMP-loaded PNVCL hydrogels were found to be cytocompatible and able to induce bio-mineralization markers in odontoblast-cells.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jaqueline Canova Paludetto Amaral, Barbara Curi Gawlinski, Cristiane Duque, Robson Frederico Cunha
Summary: This study evaluated the oral health of adolescents who participated in an oral health preventive program during their first decade of life. The results showed satisfactory outcomes in terms of caries prevention, periodontal health, and reduced prevalence of dental fluorosis.
PESQUISA BRASILEIRA EM ODONTOPEDIATRIA E CLINICA INTEGRADA
(2023)
Article
Dentistry, Oral Surgery & Medicine
Cristiane Duque, Amanda Caselato Andolfatto Souza, Kelly Limi Aida, Jesse Augusto Pereira, Karina Sampaio Caiaffa, Vanessa Rodrigues dos Santos, Leopoldo Cosme-silva, Anuradha Prakki
Summary: This study evaluated the cytotoxicity and synergistic effect of EGCG and FOSFO on biofilms of oral bacteria associated with endodontic infections. The combination of EGCG + FOSFO showed synergism against all bacterial species. EGCG and FOSFO exhibited a synergistic effect against biofilms of oral pathogens without cytotoxicity.
JOURNAL OF APPLIED ORAL SCIENCE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Cristiane Tomaz Rocha, Ana Sarah Boto Nogueira, Jordana de Andrade Almeida, Lidiany Karla Azevedo Rodrigues, Beatriz Goncalves Neves
Summary: This study evaluated the in vitro erosive effect of different analgesics on primary tooth enamel. The results showed that only Magnopyrol caused significant softening of the enamel, while Paracetamol led to morphological changes in the primary tooth enamel.
PESQUISA BRASILEIRA EM ODONTOPEDIATRIA E CLINICA INTEGRADA
(2022)
Article
Dentistry, Oral Surgery & Medicine
Engku Nasiha Engku Ngah Sayuddin, Muhammad Taher, Mohd Hafiz Arzmi, Nor Aszlitah Burhanudin, Muhamad Ashraf Rostam
Summary: This article reviews the role of podoplanin in oral cancer and its potential as a therapeutic agent. High expression of podoplanin has been observed in oral cancer and pre-cancerous lesions, suggesting that inhibitors targeting podoplanin could be effective in treating oral cancer.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Doris Haydee Rosero Salazar, Sydney Honnlee, Zi-Jun Liu
Summary: This study analyzed the dynamics and coordination of oropharyngeal muscles during natural chewing and swallowing, revealing the key role of palatal and pharyngeal muscles in chewing and the simultaneous changes in muscle activity and respiratory cycle during these processes.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Junkang Quan, Yang Liu, Lingli Ji, Yuming Zhao, Shuguo Zheng
Summary: This study identified a new DLX3 gene mutation in a Chinese family with enamel dysplasia and found that this mutation may affect ameloblast differentiation by inhibiting the transcriptional activity of Amelx/Odam/Klk4, thereby interfering with enamel formation.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Viviane Martins dos Santos Ribeiro, Mauricio Gonsalves da Costa Sousa, Paula Ribeiro Garcia, Lucas Souza dos Santos, Eliza Carla Barroso Duarte, Jose Raimundo Correa, Carlos Alberto Labate, Thais Regiani Cataldi, Rosiane Andrade da Costa, Marcelo Henrique Soller Ramada, Juliana Lott de Carvalho, Taia Maria Berto Rezende
Summary: This study compared the structural and proteomic architecture of decellularized human dental pulp using two different protocols. The results showed that the ECM preserved in the MG protocol was more intact. Proteomic analysis revealed that the MG protocol maintained around 69.56% of the proteins identified in the untreated pulp tissue, while the SG protocol only maintained 28.26%.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Jinjin Lu, Lixin Zhang, Ningxin Zhu, Dan Wang, Fei Xie, Man Qin, Yuanyuan Wang
Summary: The study investigated the effects of varying glucose concentrations on the proliferation and senescence of SHED and hBMSC. It was found that high glucose levels promoted proliferation in both cell types, but delayed senescence in SHED through autophagy inhibition and accelerated senescence in hBMSC. Additionally, the glycolysis in SHED was enhanced under high glucose culture conditions compared to hBMSC.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Luciana O. Almeida, Luan Cesar Silva, Carolina Emerick, Juliana Amorim dos Santos, Rogerio M. Castilho, Cristiane H. Squarize
Summary: This study found that the loss of PTEN signaling increases the population of HNSCC CSCs, which can be targeted by rapamycin. However, a deficiency in mTORC2 can lead to problematic selection of the parasphere CSC subtype.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Elham Mohebbi, Zainab Alimoradi, Laura S. Rozek, Azadeh Mohebbi, Elahe Jafari
Summary: This study conducted a systematic review and meta-analysis to investigate the risk of head and neck cancer among opium users. The findings showed a significant correlation between opium use and the development of head and neck cancers, particularly lip and oral cavity cancers and laryngeal cancer. This highlights the importance of further research and targeted preventive measures to address this concerning association.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Antonio Alexandre Coelho, Rute Romao Carvalho, Ana Luiza Muniz, Andre Alves Crispim, Anderson Maia Meneses, Carla Welch da Silva, Dayrine Silveira de Paula, Ana Paula Negreiros Nunes Alves, Fabricio Bitu Sousa, Paulo Goberlanio de Barros Silva
Summary: The study aimed to evaluate the role of CD20 + cells in the healing process of oral traumatic ulcers (OTU) in rats. The results showed that blocking CD20 + cells with anti-CD20 rituximab (RTX) reduced cell migration, acute inflammation, and wound healing in OTU.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Meimei Cui, Jinling Cheng, Huijuan Cheng, Ming Zhao, Dan Zhou, Min Zhang, Jingjing Jia, Limei Luo
Summary: This study explored the characteristics of human papillomavirus (HPV) in oropharyngeal carcinoma (OPC) and found that high-risk HPV infection is common in OPC patients, with higher prevalence in North America, Oceania, and Europe. Females and older patients are more susceptible to infection. Tonsil and base of tongue are the most frequent sites of infection. This study provides important theoretical basis for the prevention and treatment of OPC.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Xiaoyue Guan, Chen Shi, Yuting Wang, Yani He, Yingxue Li, Yao Yang, Wenli Mu, Wenlan Li, Tiezhou Hou
Summary: The study revealed that Gremlin1 expression levels are significantly increased in periapical lesions and may be positively correlated with IL-18 levels. Blocking Gremlin1 can significantly suppress bone resorption loss and restrain inflammatory status by affecting the activation levels of phosphorylated-CREB, ICAM-1, VCAM-1, IL-18.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Giliano Nicolini Verzeletti, Eduardo Jose Gaio, Keilla Gomes Machado, Tobias Rauber Spuldaro, Clarissa Favero Demeda, Rafaele Frassini, Andre Felipe Streck, Sidnei Moura E. Silva, Cassiano Kuchenbecker Rosing, Joao Antonio Pegas Henriques, Mariana Roesch-Ely
Summary: This study investigates the effects of D. anceps seaweed on ligature-induced experimental periodontitis in rats. The results show that D. anceps can modulate the inflammatory response and have potential therapeutic effects for periodontitis.
ARCHIVES OF ORAL BIOLOGY
(2024)