Article
Psychology, Clinical
Ellen J. Thompson, Georgina Krebs, Helena M. S. Zavos, Claire J. Steves, Thalia C. Eley
Summary: The relationship between weight and depression is bidirectional, with the direction of effects influenced by age. However, the specific causal relationship remains unclear.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Materials Science, Multidisciplinary
Meijun Chen, Changjun Zou, Wenyue Tang, Yushuang Huang, Huahong Sun
Summary: This study successfully synthesized N-doped carbon quantum dots nanoparticles (N-CQDs) nanofluid without any additives, which exhibited excellent long-term stability and enhanced thermal conductivity. The viscosity and thermal conductivity of the nanofluid were investigated and models for predicting these properties were proposed. The results showed that the synthesized N-CQDs nanofluid had great potential in improving heat transfer efficiency.
DIAMOND AND RELATED MATERIALS
(2022)
Article
Environmental Sciences
Mei An, Qingjie Guo
Summary: Previous studies have compared kinetic parameters derived from a kinetic model to those obtained using isoconversional methods to assess the accuracy of the model. However, little research has been done on the steam gasification reaction of char. This study conducted experiments using thermogravimetric analysis and compared different kinetic models to determine the best representation of the reaction. The results showed that the three-dimensional Avrami-Erofeev model accurately represents the steam gasification char reaction.
Article
Public, Environmental & Occupational Health
Huan Song, Yanan Shang, Fang Fang, Catarina Almqvist, Nancy L. Pedersen, Patrik K. E. Magnusson, Henrik Larsson, Unnur A. Valdimarsdottir
Summary: Losing a twin, especially a monozygotic one, is associated with increased mortality among the surviving twin, particularly due to unnatural causes.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Education & Educational Research
Tobias Wolfram, Damien Morris
Summary: Estimates of shared environmental influence on educational attainment using the Classical Twin Design have been found to overestimate between-family differences in educational opportunity. A new study comparing the Classical Twin Design with the Nuclear Twin and Family Design found that the latter provided a more accurate estimate of shared environmental influence, which was lower than previously thought. Additionally, the study revealed that parental education has no environmental effect on offspring education after accounting for genetic factors.
NPJ SCIENCE OF LEARNING
(2023)
Review
Behavioral Sciences
Naomi P. Friedman, Marie T. Banich, Matthew C. Keller
Summary: Twin/family studies and GWAS have their respective strengths and weaknesses, complementing and reinforcing each other rather than replacing one another.
TRENDS IN COGNITIVE SCIENCES
(2021)
Review
Engineering, Industrial
Fei Tao, Bin Xiao, Qinglin Qi, Jiangfeng Cheng, Ping Ji
Summary: This paper provides a systematic research on the current studies of digital twin modeling and conducts a comprehensive and insightful analysis of digital twin models. It also investigates and summarizes the enabling technologies and tools for digital twin modeling and presents observations and future research recommendations.
JOURNAL OF MANUFACTURING SYSTEMS
(2022)
Article
Ecology
Andrew R. Kleinhesselink, Nathan J. B. Kraft, Stephen W. Pacala, Jonathan M. Levine
Summary: Higher-order interactions (HOIs) emerge when species simultaneously compete with multiple competitors, leading to new properties not observed in isolated pairwise interactions. Ecologists face challenges in measuring and interpreting HOIs in competition models that fit real-world data, as different studies use different definitions with unclear relationships. This paper proposes a distinction between "soft" HOIs, which identify possible interaction modifications, and "hard" HOIs, which identify unique interactions in systems with three or more competitors. The authors demonstrate these differences and operationalize the definitions through a simulated competition experiment.
Article
Radiology, Nuclear Medicine & Medical Imaging
Bart de Laat, Jocelyn Hoye, Heather Liu, Evan D. Morris
Summary: The study introduced voxel-level images of drug occupancy from PET and created an EC50 image from human data to evaluate regional differences in drug affinity. Results showed spatial variation in apparent drug affinity with higher EC50 values in areas of low drug occupancy. The EC50 image could potentially enhance early-phase drug development by identifying regional differences in affinity and guiding dose selection for later-phase trials.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Review
Psychology, Biological
Fiona A. Hagenbeek, Jana S. Hirzinger, Sophie Breunig, Susanne Bruins, Dmitry V. Kuznetsov, Kirsten Schut, Veronika V. Odintsova, Dorret I. Boomsma
Summary: Twin studies compare genetic and environmental factors in identical and non-identical twins to understand behavior resemblance. Recent developments in twin studies show the need for increased representativeness. Twin concordance rates for major diseases challenge the belief in genetic determinism.
NATURE HUMAN BEHAVIOUR
(2023)
Article
Multidisciplinary Sciences
Yongning Zou, Gongjie Yao, Jue Wang
Summary: In this paper, a framework for CT image segmentation of oil rock core is proposed. The improved level set segmentation algorithm, based on the characteristics of CT images of oil rock core, has been applied with promising results.
Article
Multidisciplinary Sciences
Zhongcheng Lei, Hong Zhou, Xiaoran Dai, Wenshan Hu, Guo-Ping Liu
Summary: This paper discusses the design and implementation of a digital twin DC-DC converter for monitoring and control. The results show that the digital twin can dynamically track the converter, detect and replace faulty controllers in real time.
NATURE COMMUNICATIONS
(2023)
Review
Polymer Science
Zohaib Khurshid, Binoy Mathews Nedumgottil, Ramy Moustafa Moustafa Ali, Sompop Bencharit, Shariq Najeeb
Summary: This study critically analyzed and evaluated PEEK dental prostheses and found that they may provide a viable and more esthetic alternative to conventional prostheses. However, the long-term viability of PEEK prostheses is still uncertain due to limitations in the research.
Article
Engineering, Industrial
He Zhang, Qinglin Qi, Fei Tao
Summary: Digital twin has been widely applied in various fields, especially manufacturing, and the digital twin model is a crucial foundation in the implementation. However, there is insufficient attention on the comprehensive consistency evaluation between the models and physical objects. This paper proposes a consistency evaluation framework and method for digital twin shop-floor models.
JOURNAL OF MANUFACTURING SYSTEMS
(2022)
Article
Automation & Control Systems
QingLin Han, Xinlei Li, Manshu Dong, Guangjun Zhang
Summary: The research focuses on the geometric characteristics of bead section profile in twin-electrode GTA-AM and introduces a power-function-curve model to improve the prediction accuracy. Additionally, the tangent overlapping model is extended to address the multibead overlapping issue, providing optimal overlapping coefficient deduction for process planning. The proposed curve-fitting and overlapping models accurately predict bead behavior with a maximum error of less than 6%.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2021)
Article
Biochemical Research Methods
Christina J. Adler, Abbe White, Michelle Bockmann, Gina V. Browne, Grant Townsend, Toby Hughes
JOURNAL OF MICROBIOLOGICAL METHODS
(2018)
Article
Microbiology
Josh L. Espinoza, Derek M. Harkins, Manolito Torralba, Andres Gomez, Sarah K. Highlander, Marcus B. Jones, Pamela Leong, Richard Saffery, Michelle Bockmann, Claire Kuelbs, Jason M. Inman, Toby Hughes, Jeffrey M. Craig, Karen E. Nelson, Chris L. Dupont
Article
Microbiology
Jacquelyn M. Fechney, Gina V. Browne, Neeta Prabhu, Laszlo Irinyi, Wieland Meyer, Toby Hughes, Michelle Bockmann, Grant Townsend, Hanieh Salehi, Christina J. Adler
JOURNAL OF ORAL MICROBIOLOGY
(2019)
Article
Anthropology
Kathleen S. Paul, Christopher M. Stojanowski, Toby E. Hughes, Alan H. Brook, Grant C. Townsend
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2020)
Article
Multidisciplinary Sciences
Marcelo Freire, Ahmed Moustafa, Derek M. Harkins, Manolito G. Torralba, Yun Zhang, Pamela Leong, Richard Saffery, Michelle Bockmann, Claire Kuelbs, Toby Hughes, Jeffrey M. Craig, Karen E. Nelson
SCIENTIFIC REPORTS
(2020)
Article
Dentistry, Oral Surgery & Medicine
Shinichi Negishi, Lindsay C. Richards, Toby Hughes, Shintaro Kondo, Kazutaka Kasai
ARCHIVES OF ORAL BIOLOGY
(2020)
Article
Dentistry, Oral Surgery & Medicine
Kathleen S. Paul, Christopher M. Stojanowski, Toby Hughes, Alan Brook, Grant C. Townsend
Summary: The study reveals high levels of genetic correlation in human anterior dental morphology, particularly between corresponding teeth on both sides, and to a lesser extent among permanent dental traits. Results indicate the presence of a morphological module spanning deciduous and permanent dentition, with lower correlation among traits within individual teeth.
ARCHIVES OF ORAL BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Christina Jane Adler, Kim-Anh Le Cao, Toby Hughes, Piyush Kumar, Christine Austin
Summary: The first 1000 days of life play a crucial role in shaping the oral microbiome and oral health. However, technological limitations and statistical methods have been barriers to studying the impact of early life exposures on the oral microbiome. Understanding how early life exposures influence the oral microbiome can lead to interventions to reduce dental decay prevalence.
Article
Genetics & Heredity
Kathleen Paul, Christopher Stojanowski, Toby Hughes, Alan Brook, Grant Townsend
Summary: This study aims to understand the genetic architecture of crown morphology in the human diphyodont dentition. The results suggest that there are different genetic correlations between deciduous and permanent molars, and that m2 represents the anterior-most member of a true molar field.
Article
Anthropology
Kathleen S. Paul, Randall Feezell, Toby Hughes, Alan H. Brook
Summary: Genealogical samples that combine dental data and relatedness information are valuable for studying the biological basis of tooth variation. These samples allow for testing long-standing assumptions in bioanthropology and provide practical implications for quantitative genetic and environmental studies. Additionally, they can be used to investigate the influence of non-genetic factors on dental characters. Genealogical samples are likely to play a crucial role in generating comprehensive genotype-phenotype maps of the dentition and refining bioanthropological methods.
AMERICAN JOURNAL OF BIOLOGICAL ANTHROPOLOGY
(2023)
Meeting Abstract
Anthropology
Randall Feezell, Kathleen S. Paul, Toby Hughes, Alan Brook
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2021)
Meeting Abstract
Anthropology
Kathleen S. Paul, Christopher M. Stojanowski, Toby Hughes, Alan Brook, Grant C. Townsend
AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY
(2018)
Article
Dentistry, Oral Surgery & Medicine
Engku Nasiha Engku Ngah Sayuddin, Muhammad Taher, Mohd Hafiz Arzmi, Nor Aszlitah Burhanudin, Muhamad Ashraf Rostam
Summary: This article reviews the role of podoplanin in oral cancer and its potential as a therapeutic agent. High expression of podoplanin has been observed in oral cancer and pre-cancerous lesions, suggesting that inhibitors targeting podoplanin could be effective in treating oral cancer.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Doris Haydee Rosero Salazar, Sydney Honnlee, Zi-Jun Liu
Summary: This study analyzed the dynamics and coordination of oropharyngeal muscles during natural chewing and swallowing, revealing the key role of palatal and pharyngeal muscles in chewing and the simultaneous changes in muscle activity and respiratory cycle during these processes.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Junkang Quan, Yang Liu, Lingli Ji, Yuming Zhao, Shuguo Zheng
Summary: This study identified a new DLX3 gene mutation in a Chinese family with enamel dysplasia and found that this mutation may affect ameloblast differentiation by inhibiting the transcriptional activity of Amelx/Odam/Klk4, thereby interfering with enamel formation.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Viviane Martins dos Santos Ribeiro, Mauricio Gonsalves da Costa Sousa, Paula Ribeiro Garcia, Lucas Souza dos Santos, Eliza Carla Barroso Duarte, Jose Raimundo Correa, Carlos Alberto Labate, Thais Regiani Cataldi, Rosiane Andrade da Costa, Marcelo Henrique Soller Ramada, Juliana Lott de Carvalho, Taia Maria Berto Rezende
Summary: This study compared the structural and proteomic architecture of decellularized human dental pulp using two different protocols. The results showed that the ECM preserved in the MG protocol was more intact. Proteomic analysis revealed that the MG protocol maintained around 69.56% of the proteins identified in the untreated pulp tissue, while the SG protocol only maintained 28.26%.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Jinjin Lu, Lixin Zhang, Ningxin Zhu, Dan Wang, Fei Xie, Man Qin, Yuanyuan Wang
Summary: The study investigated the effects of varying glucose concentrations on the proliferation and senescence of SHED and hBMSC. It was found that high glucose levels promoted proliferation in both cell types, but delayed senescence in SHED through autophagy inhibition and accelerated senescence in hBMSC. Additionally, the glycolysis in SHED was enhanced under high glucose culture conditions compared to hBMSC.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Luciana O. Almeida, Luan Cesar Silva, Carolina Emerick, Juliana Amorim dos Santos, Rogerio M. Castilho, Cristiane H. Squarize
Summary: This study found that the loss of PTEN signaling increases the population of HNSCC CSCs, which can be targeted by rapamycin. However, a deficiency in mTORC2 can lead to problematic selection of the parasphere CSC subtype.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Elham Mohebbi, Zainab Alimoradi, Laura S. Rozek, Azadeh Mohebbi, Elahe Jafari
Summary: This study conducted a systematic review and meta-analysis to investigate the risk of head and neck cancer among opium users. The findings showed a significant correlation between opium use and the development of head and neck cancers, particularly lip and oral cavity cancers and laryngeal cancer. This highlights the importance of further research and targeted preventive measures to address this concerning association.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Antonio Alexandre Coelho, Rute Romao Carvalho, Ana Luiza Muniz, Andre Alves Crispim, Anderson Maia Meneses, Carla Welch da Silva, Dayrine Silveira de Paula, Ana Paula Negreiros Nunes Alves, Fabricio Bitu Sousa, Paulo Goberlanio de Barros Silva
Summary: The study aimed to evaluate the role of CD20 + cells in the healing process of oral traumatic ulcers (OTU) in rats. The results showed that blocking CD20 + cells with anti-CD20 rituximab (RTX) reduced cell migration, acute inflammation, and wound healing in OTU.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Meimei Cui, Jinling Cheng, Huijuan Cheng, Ming Zhao, Dan Zhou, Min Zhang, Jingjing Jia, Limei Luo
Summary: This study explored the characteristics of human papillomavirus (HPV) in oropharyngeal carcinoma (OPC) and found that high-risk HPV infection is common in OPC patients, with higher prevalence in North America, Oceania, and Europe. Females and older patients are more susceptible to infection. Tonsil and base of tongue are the most frequent sites of infection. This study provides important theoretical basis for the prevention and treatment of OPC.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Xiaoyue Guan, Chen Shi, Yuting Wang, Yani He, Yingxue Li, Yao Yang, Wenli Mu, Wenlan Li, Tiezhou Hou
Summary: The study revealed that Gremlin1 expression levels are significantly increased in periapical lesions and may be positively correlated with IL-18 levels. Blocking Gremlin1 can significantly suppress bone resorption loss and restrain inflammatory status by affecting the activation levels of phosphorylated-CREB, ICAM-1, VCAM-1, IL-18.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Giliano Nicolini Verzeletti, Eduardo Jose Gaio, Keilla Gomes Machado, Tobias Rauber Spuldaro, Clarissa Favero Demeda, Rafaele Frassini, Andre Felipe Streck, Sidnei Moura E. Silva, Cassiano Kuchenbecker Rosing, Joao Antonio Pegas Henriques, Mariana Roesch-Ely
Summary: This study investigates the effects of D. anceps seaweed on ligature-induced experimental periodontitis in rats. The results show that D. anceps can modulate the inflammatory response and have potential therapeutic effects for periodontitis.
ARCHIVES OF ORAL BIOLOGY
(2024)