Article
Dentistry, Oral Surgery & Medicine
Mohamed Mahmoud Abdalla, Mohammed Nadeem Bijle, Nermeen M. A. Abdallah, Cynthia Kar Yung Yiu
Summary: The addition of 4% CSR to a NaF varnish significantly enhanced its enamel remineralization and antimicrobial potential with no cytotoxic effect.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Leona Guntermann, Arno Rohrbach, Edgar Schaefer, Till Dammaschke
Summary: This study evaluated the remineralization potential and protection against demineralization of hydroxyapatite-containing toothpaste (Karex) compared to fluoride-containing toothpaste (Elmex) and fluoride- and hydroxyapatite-free toothpaste (Ajona). The results showed that Elmex had the highest remineralization effect, while Karex had the lowest.
HEAD & FACE MEDICINE
(2022)
Article
Chemistry, Physical
Zeynep Ergucu, Inci Yoruk, Aysegul Erdogan, Hayal Boyacioglu, Robert Hill, Aylin Baysan
Summary: This study investigated the effects of toothpaste containing calcium sodium phospho-silicate bioglass (NovaMin) or calcium fluorosilicate bioglass (BioMinF) on the surface mineral composition and morphology of enamel after a bleaching procedure. The results showed that there was no significant decrease in the Ca% and P% values of enamel after bleaching when using different toothpaste formulations for 45 days. However, the toothpaste containing calcium fluorosilicate bioglass (BioMinF) had higher Ca% and P% values on bleached enamel.
Article
Multidisciplinary Sciences
Andrei Cristian Ionescu, Lorenzo Degli Esposti, Michele Iafisco, Eugenio Brambilla
Summary: This study characterized, tested, and compared the structure and performance of remineralizing toothpastes and topical mousses. It found that formulations containing calcium-phosphate bioactive nanocompounds were able to promote enamel remineralization and dentinal tubules occlusion. The presence of doping elements and casein phosphopeptide was essential for achieving these effects. Topical mousses showed a higher capability for dentinal tubules occlusion compared to toothpastes.
SCIENTIFIC REPORTS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Haoran Chen, Robert Hill, Aylin Baysan
Summary: This study investigated the effect of different toothpastes containing 5,000ppm-F, 1,450ppm-F or bioactive glass (BG) with 540ppm-F on artificial root carious lesions. The toothpaste containing BG released more ions (Ca2+ and P) and rehardened the lesions, indicating potential clinical significance.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Min-Kyung Kang, Hee-Eun Kim
Summary: This study evaluated the remineralizing efficacy of fluoride using a pH-cycling model with oral microcosm biofilms. Results showed that the presence of biofilms significantly influenced fluoride remineralization on early carious lesions. The fluoride-treated group with oral biofilms experienced lower ΔΔF compared to the group without biofilms, highlighting the importance of considering biofilm presence in assessing fluoride efficacy.
JOURNAL OF DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
John Yun Niu, Iris Xiaoxue Yin, William Ka Kei Wu, Quan-Li Li, May Lei Mei, Chun Hung Chu
Summary: The dual-action peptide GA-KR12 showed antibiofilm effects by inhibiting the growth of Streptococcus mutans biofilm, and also demonstrated remineralising effects by promoting the remineralisation of enamel caries. The mineral losses and calcium-to-phosphorus ratios were significantly lower in the GA-KR12-treated group compared to the control group, indicating the potential of GA-KR12 in preventing enamel caries and promoting enamel remineralisation.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Wen Jiang, Gang Wang, Wenzhi Wu, Changyu Shao, Haihua Pan, Zhi Chen, Ruikang Tang, Zhuo Chen, Zhijian Xie
Summary: This study evaluated the properties of calcium phosphate ion clusters (CPICs) materials and compared them with Duraphat and Icon. The results showed that CPICs demonstrated promising remineralisation, mechanical, anti-aging, acid resistance, and antibacterial properties.
AUSTRALIAN ENDODONTIC JOURNAL
(2023)
Article
Medicine, General & Internal
Rikki Deswal, Navneet Kukreja, Swati Chhabra, Shivangi Trivedi, Ankita Sharma, Anamika Thakur
Summary: This study aimed to compare and evaluate the remineralizing efficiency of Remin Pro, tricalcium phosphate, and HealOzone on enamel. The results showed that all three remineralizing agents significantly improved the remineralization of enamel compared to the control group.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Polymer Science
Ali Azhar Dawasaz, Rafi Ahmad Togoo, Zuliani Mahmood, Ahmad Azlina, Kannan Thirumulu Ponnuraj
Summary: Due to limitations of fluoride therapy in dental caries prevention, newer preventive agents like P11-4 peptide have been developed. P11-4 peptide can facilitate biomimetic remineralisation and has a positive effect on early carious lesions. However, better results can be achieved when it is combined with other agents.
Review
Dentistry, Oral Surgery & Medicine
Iliana Gehui Yan, Faith Miaomiao Zheng, Sherry Shiqian Gao, Duangporn Duangthip, Edward Chin Man Lo, Chun Hung Chu
Summary: The aim of this study was to review the protocol of using silver diamine fluoride (SDF) for arresting caries, specifically focusing on the application time. The results showed that there were variations in the published protocols, with most suggesting an SDF application time of 60 seconds, which may be lengthy for young children and older adults.
INTERNATIONAL DENTAL JOURNAL
(2022)
Article
Materials Science, Ceramics
S. V. Kuznetsov, Yu. A. Ermakova, K. N. Boldyrev, V. S. Sedov, A. A. Alexandrov, V. V. Voronov, S. Kh. Batygov, A. D. Rezaeva, A. R. Drobysheva, N. Yu. Tabachkova
Summary: Novel scintillating and visualizing materials are crucial for the development of high-power X-ray sources. This study focuses on the formation of composite materials consisting of X-ray luminescent nanoparticles in a robust transparent matrix. Sr0.85-xBaxEu0.15F2.15 nanopowders were synthesized and the most optimal composition with the brightest luminescence response was determined.
CERAMICS INTERNATIONAL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Nayara Goncalves Emerenciano, Alberto Carlos Botazzo Delbem, Francyenne Maira Castro Goncalves, Julia Paiao Quinterio, Emerson Rodrigues de Camargo, Yara Teresinha Correa Silva-Sousa, Marcelle Danelon
Summary: The addition of 0.25% nano-sized beta-CaGPn to 1100F formulation increased the bioavailability of calcium and phosphate, promoting a higher level of remineralization.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Mohammed Nadeem Bijle, Usman Ashraf, Mohamed Mahmoud Abdalla, Cynthia Kar Yung Yiu
Summary: The study showed that higher concentrations of arginine in 5% sodium fluoride varnish can modulate the biochemical composition of biofilm on treated enamel. There were differences in carbohydrate, protein, amyloid, and eDNA content in biofilms treated with 2% and 4% Arg-NaF compared to controls. Additionally, the proportion of biofilm EPS matrix to bacteria was reduced in Arg-NaF groups.
JOURNAL OF DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Mohammed Nadeem Bijle, Mohamed Mahmoud Abdalla, Usman Ashraf, Manikandan Ekambaram, Cynthia Kar Yung Yiu
Summary: The arginine-fluoride (Arg-NaF) varnishes demonstrated enhanced enamel fluoride uptake and remineralization potential, showing promise as a caries-preventive regimen. Increasing arginine concentration improved the effectiveness of the varnish while reducing plaque fluoride uptake.
JOURNAL OF DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Engku Nasiha Engku Ngah Sayuddin, Muhammad Taher, Mohd Hafiz Arzmi, Nor Aszlitah Burhanudin, Muhamad Ashraf Rostam
Summary: This article reviews the role of podoplanin in oral cancer and its potential as a therapeutic agent. High expression of podoplanin has been observed in oral cancer and pre-cancerous lesions, suggesting that inhibitors targeting podoplanin could be effective in treating oral cancer.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Doris Haydee Rosero Salazar, Sydney Honnlee, Zi-Jun Liu
Summary: This study analyzed the dynamics and coordination of oropharyngeal muscles during natural chewing and swallowing, revealing the key role of palatal and pharyngeal muscles in chewing and the simultaneous changes in muscle activity and respiratory cycle during these processes.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Junkang Quan, Yang Liu, Lingli Ji, Yuming Zhao, Shuguo Zheng
Summary: This study identified a new DLX3 gene mutation in a Chinese family with enamel dysplasia and found that this mutation may affect ameloblast differentiation by inhibiting the transcriptional activity of Amelx/Odam/Klk4, thereby interfering with enamel formation.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Viviane Martins dos Santos Ribeiro, Mauricio Gonsalves da Costa Sousa, Paula Ribeiro Garcia, Lucas Souza dos Santos, Eliza Carla Barroso Duarte, Jose Raimundo Correa, Carlos Alberto Labate, Thais Regiani Cataldi, Rosiane Andrade da Costa, Marcelo Henrique Soller Ramada, Juliana Lott de Carvalho, Taia Maria Berto Rezende
Summary: This study compared the structural and proteomic architecture of decellularized human dental pulp using two different protocols. The results showed that the ECM preserved in the MG protocol was more intact. Proteomic analysis revealed that the MG protocol maintained around 69.56% of the proteins identified in the untreated pulp tissue, while the SG protocol only maintained 28.26%.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Jinjin Lu, Lixin Zhang, Ningxin Zhu, Dan Wang, Fei Xie, Man Qin, Yuanyuan Wang
Summary: The study investigated the effects of varying glucose concentrations on the proliferation and senescence of SHED and hBMSC. It was found that high glucose levels promoted proliferation in both cell types, but delayed senescence in SHED through autophagy inhibition and accelerated senescence in hBMSC. Additionally, the glycolysis in SHED was enhanced under high glucose culture conditions compared to hBMSC.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Luciana O. Almeida, Luan Cesar Silva, Carolina Emerick, Juliana Amorim dos Santos, Rogerio M. Castilho, Cristiane H. Squarize
Summary: This study found that the loss of PTEN signaling increases the population of HNSCC CSCs, which can be targeted by rapamycin. However, a deficiency in mTORC2 can lead to problematic selection of the parasphere CSC subtype.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Elham Mohebbi, Zainab Alimoradi, Laura S. Rozek, Azadeh Mohebbi, Elahe Jafari
Summary: This study conducted a systematic review and meta-analysis to investigate the risk of head and neck cancer among opium users. The findings showed a significant correlation between opium use and the development of head and neck cancers, particularly lip and oral cavity cancers and laryngeal cancer. This highlights the importance of further research and targeted preventive measures to address this concerning association.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Antonio Alexandre Coelho, Rute Romao Carvalho, Ana Luiza Muniz, Andre Alves Crispim, Anderson Maia Meneses, Carla Welch da Silva, Dayrine Silveira de Paula, Ana Paula Negreiros Nunes Alves, Fabricio Bitu Sousa, Paulo Goberlanio de Barros Silva
Summary: The study aimed to evaluate the role of CD20 + cells in the healing process of oral traumatic ulcers (OTU) in rats. The results showed that blocking CD20 + cells with anti-CD20 rituximab (RTX) reduced cell migration, acute inflammation, and wound healing in OTU.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Meimei Cui, Jinling Cheng, Huijuan Cheng, Ming Zhao, Dan Zhou, Min Zhang, Jingjing Jia, Limei Luo
Summary: This study explored the characteristics of human papillomavirus (HPV) in oropharyngeal carcinoma (OPC) and found that high-risk HPV infection is common in OPC patients, with higher prevalence in North America, Oceania, and Europe. Females and older patients are more susceptible to infection. Tonsil and base of tongue are the most frequent sites of infection. This study provides important theoretical basis for the prevention and treatment of OPC.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Xiaoyue Guan, Chen Shi, Yuting Wang, Yani He, Yingxue Li, Yao Yang, Wenli Mu, Wenlan Li, Tiezhou Hou
Summary: The study revealed that Gremlin1 expression levels are significantly increased in periapical lesions and may be positively correlated with IL-18 levels. Blocking Gremlin1 can significantly suppress bone resorption loss and restrain inflammatory status by affecting the activation levels of phosphorylated-CREB, ICAM-1, VCAM-1, IL-18.
ARCHIVES OF ORAL BIOLOGY
(2024)
Article
Dentistry, Oral Surgery & Medicine
Giliano Nicolini Verzeletti, Eduardo Jose Gaio, Keilla Gomes Machado, Tobias Rauber Spuldaro, Clarissa Favero Demeda, Rafaele Frassini, Andre Felipe Streck, Sidnei Moura E. Silva, Cassiano Kuchenbecker Rosing, Joao Antonio Pegas Henriques, Mariana Roesch-Ely
Summary: This study investigates the effects of D. anceps seaweed on ligature-induced experimental periodontitis in rats. The results show that D. anceps can modulate the inflammatory response and have potential therapeutic effects for periodontitis.
ARCHIVES OF ORAL BIOLOGY
(2024)