Article
Medicine, General & Internal
Malia S. Q. Murphy, Robin Ducharme, Steven Hawken, Daniel J. Corsi, William Petrcich, Darine El-Chaar, Lise Bisnaire, Daniel I. McIsaac, Deshayne B. Fell, Shi Wu Wen, Mark C. Walker
Summary: This study found that intrapartum epidural analgesia was associated with a small increase in the risk of ASD in offspring. However, the biological plausibility of this association remains unclear, and caution should be exercised when interpreting the findings.
Article
Obstetrics & Gynecology
Gabriel Levin, Abraham Tsur, Lee Tenenbaum, Nizan Mor, Michal Zamir, Raanan Meyer
Summary: The study found that TOLAC among grand-multiparous women has a high success rate, and shortening the duration of ruptured membranes is a modifiable factor that may increase TOLAC success rates.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Chemistry, Medicinal
Wan-Yi Rao, Fang Xu, Shao-Bing Dai, Zhong Mei, Xiao-Ping Chen, Chang-Cheng Lv, Chun-Lei Liu, Warwick Ngan Kee, Xin-Zhong Chen
Summary: This study compared three different anesthesia techniques and found that DPE anesthesia had a faster onset, shorter duration of surgical sensory block, lower incidence of intraoperative pain, and higher patient satisfaction compared to EA anesthesia. Additionally, DPE anesthesia had less impact on maternal hemodynamic parameters compared to CSE anesthesia, suggesting its effectiveness in obstetric surgery.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2023)
Article
Obstetrics & Gynecology
Chan Shen, Lin Chen, Chengjin Yue, Jing Cheng
Summary: This study investigated the effectiveness of extending epidural analgesia for intrapartum cesarean section. The results showed that using a well-functioning epidural catheter for extending epidural analgesia may be a reliable and effective anesthetic method.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Review
Medicine, General & Internal
Dingfeng Zhang, Stephanie-May Ruchat, Cristina Silva-Jose, Javier Gil-Ares, Ruben Barakat, Miguel Sanchez-Polan
Summary: This article aimed to investigate the effect of physical activity during pregnancy on the type of delivery, the duration of labor, and the use of epidurals. The study found that physical activity during pregnancy can reduce the risk of cesarean section and instrumental delivery, as well as shorten the duration of the first stage of labor.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Maya Ram, Liran Hiersch, Eran Ashwal, Yariv Yogev, Amir Aviram
Summary: This study compared pregnancy outcomes in grand-multiparous women with and without previous cesarean delivery, and evaluated the number of successful vaginal deliveries needed after a CD to reduce the complication rate of trials of labor. The results showed that the presence of a single previous VBAC increased the odds of achieving a vaginal delivery in the next TOLAC, while multiple prior VBACs did not increase the odds of another successful VBAC.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2021)
Article
Obstetrics & Gynecology
Misgav Rottenstreich, Reut Rotem, Arnon Samueloff, Hen Y. Sela, Sorina Grisaru-Granovsky
Summary: This study aimed to evaluate the success rates of vaginal birth after cesarean (VBAC) and the maternal and neonatal outcomes associated with trial of labor after cesarean in grand multiparous women. The results showed that trial of labor after cesarean in grand multiparous women is associated with favorable maternal and neonatal outcomes, although there is an increased risk of postpartum hemorrhage.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Maria Regina Torloni, Monica Siaulys, Rachel Riera, Ana Luiza Cabrera Martimbianco, Rafael Leite Pacheco, Carolina de Oliveira Cruz Latorraca, Mariana Widmer, Ana Pilar Betran
Summary: In women undergoing pre-labor cesarean section, prophylactic oxytocin administration before or after fetal delivery showed no significant differences in postpartum hemorrhage, nausea/vomiting, blood transfusion, or hysterectomy. However, earlier administration reduced blood loss volume and need for additional uterotonics. Limited evidence suggests no significant differences between prophylactic oxytocin administration before or after placental separation on PPH, need for additional uterotonic, or nausea/vomiting.
Article
Medicine, General & Internal
Rachel J. Kearns, Martin Shaw, Piotr S. Gromski, Stamatina Iliodromiti, Deborah A. Lawlor, Scott M. Nelson
Summary: This population-based cohort study in Scotland found that labor epidural analgesia was not independently associated with adverse neonatal or childhood development outcomes. Associations with neonatal resuscitation and admission were likely mediated by mode of delivery.
Article
Anesthesiology
Shuzhi Luo, Zhaowen Chen, Xujian Wang, Changyu Zhu, Shili Su
Summary: Labor epidural analgesia for multiparous women can effectively relieve labor pain, but may prolong labor, increase blood loss, and lower Apgar scores. The timing of LEA initiation should be defined based on cervical dilation to better understand its effects.
BMC ANESTHESIOLOGY
(2021)
Article
Obstetrics & Gynecology
Aleksandra Olszynska, Zofia Di Martino, Agnieszka Pawlowska, Stepan Feduniw, Jan Modzelewski, Anna Kajdy, Dorota Sys, Grazyna Baczek, Michal Rabijewski
Summary: This study aimed to investigate the effect of epidural analgesia (EA) on the duration of labor and delivery mode. The results showed that patients receiving EA had longer labor duration but it didn't affect neonatal outcomes. Moreover, the risk of emergency Cesarean section in nulliparas with EA was three times lower.
GINEKOLOGIA POLSKA
(2023)
Article
Health Care Sciences & Services
Dorota Sys, Anna Kajdy, Martyna Nizniowska, Barbara Baranowska, Dorota Raczkiewicz, Urszula Tataj-Puzyna
Summary: This study examines the experiences and preferences of women giving birth after a previous cesarean section. The research shows that while many women prefer vaginal birth, a significant number end up having another cesarean section. Therefore, it is important for hospitals to support women's birth preferences after a cesarean section (if medically appropriate), providing comprehensive counseling, resources, and emotional support to ensure informed decisions and positive birth experiences.
Article
Obstetrics & Gynecology
Roy Lauterbach, Naphtali Justman, Yuval Ginsberg, Yoav Siegler, Gal Bachar, Dana Vitner, Chen Ben-David, Yaniv Zipori, Ron Beloosesky, Zeev Weiner, Nizar Khatib
Summary: This study aims to evaluate the effects of extending the second stage of labor in women attempting a trial of labor after a cesarean section (TOLAC). A retrospective cohort study comparing two periods found that extending the second stage to 3 hours significantly decreased repeat cesarean delivery rate, but also increased instrumental delivery rates, uterine rupture, fetal acidemia, and neonatal intensive care unit admissions. These findings suggest the need for further consideration of allowing a prolonged second stage in TOLAC patients.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Obstetrics & Gynecology
Erica Bavenas, Christoffer Moller, Prashant Bhandarkar, Jude Mulowooza, Jenny Lofgren
Summary: The study identified predictors of poor neonatal outcomes after cesarean section in Uganda, with uterine rupture and hemorrhage being associated with the highest mortality and stillbirth rates. Emergency surgery and general anesthesia led to worse neonatal outcomes compared to elective surgery and spinal anesthesia. Planning elective surgeries and increasing the use of spinal anesthesia may help reduce stillbirths and immediate neonatal deaths.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2022)
Article
Pharmacology & Pharmacy
Wenping Xu, Dan Michael Drzymalski, Ling Ai, Hanqing Yao, Lin Liu, Fei Xiao
Summary: The initial infusion dose of 0.1 µg/kg/min of norepinephrine was effective in preventing spinal anesthesia-induced hypotension.
FRONTIERS IN PHARMACOLOGY
(2021)