Article
Nutrition & Dietetics
Shohei Kuraoka, Masako Oda, Hiroshi Mitsubuchi, Kimitoshi Nakamura, Takahiko Katoh
Summary: There is a link between vitamin D deficiency and impaired height growth in young children, regardless of stature. Reduced outdoor activity, especially during winter, increases the risk of vitamin D deficiency.
Review
Endocrinology & Metabolism
John P. Bilezikian, Neil Binkley, Hector F. De Luca, Angelo Fassio, Anna Maria Formenti, Ghada El-Hajj Fuleihan, Annemieke C. Heijboer, Andrea Giustina
Summary: This work reviews and discusses controversial topics regarding vitamin D, SARS-CoV-2 infection, and COVID-19. The International Conferences Controversies in Vitamin D are workshops that started in 2017 and feature international experts and leaders in the field. The fifth annual conference was held in Stresa, Italy, in September 2021.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Nutrition & Dietetics
Ola Hysaj, Patricia Marques-Gallego, Aline Richard, Magdeldin Elgizouli, Alexandra Nieters, Katharina C. Quack Lotscher, Sabine Rohrmann
Summary: This study assessed parathyroid hormone concentrations in pregnant women during early and late pregnancy, finding an inverse correlation between serum 25(OH)D and PTH levels. Statistically significant determinants of PTH concentrations included 25(OH)D levels, season, parity, and partner's education in early pregnancy, while late pregnancy was affected by 25(OH)D levels and country of origin. These factors seem to primarily impact PTH through 25(OH)D, but may also have other mechanisms of influence.
Article
Biochemistry & Molecular Biology
Luisa Pellegrino, Franca Marangoni, Giovanna Muscogiuri, Paolo D'Incecco, Guillaume T. Duval, Cedric Annweiler, Annamaria Colao
Summary: Vitamin D is crucial for bone health as well as overall health, but its deficiency is common worldwide. Fortifying food such as milk is recommended to address this issue and promote adequate intake of this essential vitamin.
Article
Medicine, General & Internal
Antonio Corsello, Giulia C. I. Spolidoro, Gregorio P. Milani, Carlo Agostoni
Summary: In recent years, researchers have focused on the potential role of vitamin D in various disorders, including autoimmune and infectious diseases. Although vitamin D deficiency remains a major public health problem, its symptomatic manifestations are becoming less common in clinical practice, particularly in pediatric age. However, there is a lack of consensus among clinicians regarding the definitions of deficiency and insufficiency, especially after the first year of life. This opinion paper aims to summarize recent evidence on vitamin D status and supplementation in pediatrics, in order to establish a common definition of deficiency and raise awareness among clinicians.
FRONTIERS IN MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Ming-Yieh Peng, Wen-Chih Liu, Jing-Quan Zheng, Chien-Lin Lu, Yi-Chou Hou, Cai-Mei Zheng, Jenn-Yeu Song, Kuo-Cheng Lu, You-Chen Chao
Summary: Vitamin D plays a crucial role in combating COVID-19 by enhancing the immune system, increasing ACE2 expression, and inhibiting the activity of the RAS system. Medical studies have shown that adequate intake of vitamin D is inversely correlated with the incidence and severity of COVID-19.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Astronomy & Astrophysics
O. Khabarova, O. Malandraki, H. Malova, R. Kislov, A. Greco, R. Bruno, O. Pezzi, S. Servidio, Gang Li, W. Matthaeus, J. Le Roux, N. E. Engelbrecht, F. Pecora, L. Zelenyi, V Obridko, V Kuznetsov
Summary: Recent studies in the heliosphere have shifted the focus from a 2D perspective to a more comprehensive understanding of 3D processes, revealing previously unimaginable dynamics through simulations and observations. Current research is centered on exploring plasma structures and their observations in the heliosphere.
SPACE SCIENCE REVIEWS
(2021)
Review
Endocrinology & Metabolism
Marcela Moraes Mendes, Patricia Borges Botelho, Helena Ribeiro
Summary: Vitamin D is crucial for musculoskeletal health, enhancing calcium absorption and bone mineralization and promoting muscle function. However, low vitamin D levels can lead to bone loss and muscle weakness. There is a need for consistent data to establish realistic recommendations for vitamin D status, as there is currently a lack of consensus on thresholds for deficiency and optimal levels, as well as the best intake and supplementation strategies and the extra-skeletal effects of vitamin D.
ENDOCRINE CONNECTIONS
(2022)
Review
Endocrinology & Metabolism
Glenville Jones
Summary: This article provides a unique perspective on the discovery of vitamin D and its deficiency disease, rickets, covering four distinct historical phases and highlighting major developments in the field.
ENDOCRINE CONNECTIONS
(2022)
Review
Pharmacology & Pharmacy
Sofie-Louise Feentved Odum, Martin Kongsbak-Wismann
Summary: The impact of the SARS-CoV-2 virus causing the COVID-19 pandemic has been severe worldwide. There is no clear consensus on whether vitamin D supplementation affects the burden of COVID-19. Various studies have shown different results, with some suggesting a beneficial effect of vitamin D on disease severity and mortality, while others found no such effects. Investigating the role of the vitamin D receptor (VDR) in immune responses to SARS-CoV-2 can provide insights into the lack of consensus.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2023)
Article
Nutrition & Dietetics
Lorena Villalba-Heredia, Cristina Comeras-Chueca, Alejandro Gonzalez-Aguero, Daniel Domingo-del-Val, Pilar Calmarza, German Vicente-Rodriguez, Jose A. Casajus, Angel Matute-Llorente
Summary: The study found no significant relationship between serum 25-hydroxyvitamin D and cardiorespiratory fitness parameters in prepubertal obese and overweight children. However, the cardiorespiratory fitness of these children was found to be relatively poor compared to normal-weight children.
Article
Criminology & Penology
Robert G. Maunder, Lesley Wiesenfeld, Andrea Lawson, Jonathan J. Hunter
Summary: The study found that childhood abuse or neglect was associated with clinical complexity in adult outpatients, with these patients more likely to have other indices of complexity and experience psychological distress and disability. Childhood abuse or neglect may result in suboptimal outcomes to standard care, necessitating more comprehensive and trauma-informed treatments.
JOURNAL OF INTERPERSONAL VIOLENCE
(2021)
Article
Nutrition & Dietetics
Spyridon N. Karras, Erdinc Dursun, Merve Alaylioglu, Duygu Gezen-Ak, Fatme Al Anouti, Stefan Pilz, Pawel Pludowski, Edward Jude, Kalliopi Kotsa
Summary: Dysregulation of vitamin D-binding protein has been associated with various pregnancy complications. The effects of VDBP polymorphisms on adipokine profiles in mothers and neonates have not been fully investigated. This study found that VDBP polymorphisms had minimal impact on adiponectin, irisin, and VDBP concentrations at birth under different vitamin D status cut-offs.
Article
Medicine, Research & Experimental
Jesse Cottrell, Chelsea Nelson, Catherine Waldron, Mackenzie Bergeron, Abigail Samson, Monica Valentovic
Summary: This study found multiple associations between umbilical cord essential and toxic elements, thyroid levels, and Vitamin D on childhood development. Calcium, magnesium, copper, zinc, and manganese were associated with language and motor development. Thyroid hormone levels were associated with cognitive and physical milestones, while Vitamin D was associated with delays in fine motor development.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Nutrition & Dietetics
Andreea Bianca Stoica, Claudiu Marginean
Summary: This article reviews the impact of vitamin D deficiency on the health of infants, emphasizing its global significance and the need for further research and strategies. While conflicting results exist regarding the effects of vitamin D, it is clear that deficiency has significant implications, particularly for infants.