期刊
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY
卷 27, 期 5, 页码 510-519出版社
OXFORD UNIV PRESS
DOI: 10.1093/arclin/acs056
关键词
Alzheimers disease; Dementia; Elderly; geriatrics; aging; Learning and memory; Mild cognitive impairment; Statistical methods
资金
- Swiss National Science Foundation [NF 32-49107.96]
- Swiss National Science Foundation Ambizione Fellowship
- Novartis Foundation, Basel, Switzerland
Episodic memory is affected early in the course of dementia. Two well-established tests to assess verbal episodic memory functioning are the Word List task from the Consortium to Establish a Registry for Alzheimers disease Neuropsychological Assessment Battery (CERAD-NAB) and the California Verbal Learning Test (CVLT). In clinical and/or research settings, patients are typically administered either one or the other test, making statistical comparisons difficult. This study aimed to (i) compare the z-scores of these two tests in patients with MCI and different types of dementia and (ii) establish formulae to transform CERAD-NAB scores into CVLT scores and vice versa. Sixty-five patients completed both tests for the first time and within 10 days of each other. Pearson correlation coefficients indicated that the two tests assess similar aspects of episodic memory and that the CVLT is more sensitive to subtle episodic memory impairments. Finally, conversion formulae are provided and their implementation illustrated.
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