4.2 Article

Robust and Expanded Norms for the Dementia Rating Scale

期刊

ARCHIVES OF CLINICAL NEUROPSYCHOLOGY
卷 25, 期 5, 页码 347-358

出版社

OXFORD UNIV PRESS
DOI: 10.1093/arclin/acq030

关键词

Dementia Rating Scale; DRS; Alzheimer's disease; Robust; Norms

资金

  1. National Institutes of Health [NS054722, AG00831, AG016574, AG006786]
  2. State of Florida Alzheimer's Disease Initiative [FL-2J-02]

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The Dementia Rating Scale (DRS) is a widely used measure of global cognition, with age- and education-corrected norms derived from a cross-sectional sample of adults participating in Mayo's Older Americans Normative Studies (MOANS). In recent years, however, studies have indicated that cross-sectional normative samples of older adults represent an admixture of individuals who are indeed cognitively normal (i.e., disease-free) and individuals with incipient neurodegenerative disease. Theoretically, the contamination of cross-sectional normative samples with cases of preclinical dementia can lead to underestimation of the test mean and overestimation of the variance, thus reducing the clinical utility of the norms. Robust norming, in which dementia cases are removed from the normative cohort through longitudinal follow-up, is an alternative approach to norm development. The current study presents a reappraisal of the original MOANS DRS norms, provides robust and expanded norms based on a sample of 894 adults age 55 and over, and critically evaluates the benefits of robust norming.

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