Article
Biochemistry & Molecular Biology
Azza A. A. Attia, Jehan M. M. Sorour, Neama A. A. Mohamed, Tagreed T. T. Mansour, Rasha A. A. Al-Eisa, Nahla S. S. El-Shenawy
Summary: This study aimed to investigate the protective role of vitamin E in improving cardiotoxicity induced by cyclophosphamide in rats. The results showed that vitamin E could attenuate the elevation of cardiac markers, increase in lipid profiles, reduction in antioxidant enzyme activities, and increase in lipid peroxidation. In addition, vitamin E was found to improve the histopathological alterations caused by cyclophosphamide.
Article
Plant Sciences
Ivna Stolfa Camagajevac, Rosemary Vukovic, Kristina Vukovic, Ana Vukovic, Vladimir Ivezic, Tanja Zuna Pfeiffer, Ljiljana Krstin, Zdenko Loncaric
Summary: This study evaluated the leaf antioxidative responses of three wheat varieties treated with two forms of zinc commonly used in agronomic biofortification. The results showed that both forms of zinc treatment induced oxidative stress in wheat leaves.
Article
Food Science & Technology
Maria Galvez-Llompart, Riccardo Zanni, Lara Manyes, Giuseppe Meca
Summary: Machine learning models based on quantitative structure-activity relationship (QSAR) were used to predict the lipid peroxidation activity of mycotoxins. Two algorithms, Linear Discriminant Analysis (LDA) and Artificial Neural Networks (ANNs), were trained and achieved high classification rates. These models provide a fast, accurate, and cost-effective means to assess mycotoxin toxicity and mechanism of action.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jakub Pastuszak, Anna Szczerba, Michal Dziurka, Marta Hornyak, Przemyslaw Kopec, Marek Szklarczyk, Agnieszka Plazek
Summary: This study identified physiological or biochemical markers of durum wheat resistance to F. culmorum, helping to formulate a strategy for rapid evaluation of disease severity and selection of plants with higher level of resistance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Paper & Wood
Aisha M. H. Al-Rajhi, Reham Yahya, Mohamed M. Alawlaqi, Mohamed A. Fareid, Basma H. Amin, Tarek M. Abdelghani
Summary: The research demonstrates that copper oxide nanoparticles have a significant inhibitory effect on the growth and mycotoxins of Fusarium incarnatum, especially at a concentration of 400 ppm.
Article
Plant Sciences
Biswajit Bose, Suman Kumaria, Pramod Tandon
Summary: The study found that Jatamansi grows better in conditions of low temperature and higher light intensity, achieving higher regeneration rates and shoot numbers. Through in vitro propagation, genetic fidelity of the species was maintained, and increased antioxidant enzyme activities were observed under oxidative stress conditions.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Article
Biochemistry & Molecular Biology
Hanna Lesiewska, Alina Wozniak, Pawel Reisner, Krzysztof Czosnyka, Joanna Stachura, Grazyna Malukiewicz
Summary: Oxidative stress and depletion of antioxidant defenses may contribute to cataract incidence in patients under 60 years. This study measured antioxidant enzyme activity, vitamin concentrations, and oxidative stress markers in cataract patients and controls. The results showed lower activity of antioxidant enzymes and lower concentrations of vitamins A and E in cataract patients. Additionally, higher levels of lipid peroxidation and protein oxidation were observed, indicating increased oxidative stress in cataract patients. Supplementation with antioxidants could be beneficial for this group of patients.
Article
Fisheries
Fawzy Magouz, Hasnaa Abu-Ghanima, Amr Zaineldin, Mahmoud S. Gewaily, Ali Soliman, Asem A. Amer, Eman M. Moustafa, Elsayed M. Younis, Abdel-Wahab A. Abdel-Warith, Simon J. Davies, Hien Van Doan, Wanaporn Tapingkae, Mahmoud A. O. Dawood
Summary: In this study, it was found that Bacillus subtilis can alleviate the negative effects of mycotoxins on Mullet performance, while ochratoxin A reduces performance. Additionally, dietary supplementation of Bacillus subtilis can improve fish growth, immune system function, and reduce pathological effects, while ochratoxin A has adverse effects on fish health.
AQUACULTURE REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Priscila Ortega, Hector Aguilar Vitorino, Shadaesha Green, Flavia P. Zanotto, J. Sook Chung, Renata G. Moreira
Summary: The study showed that in crabs from highly contaminated areas, cadmium bioaccumulation, oxidative stress, and hormone levels were higher compared to those from lightly contaminated areas, while the transcripts of crustacean hyperglycemic hormone and molt-inhibiting hormone decreased.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Review
Food Science & Technology
Marcin Bryla, Adam Pierzgalski, Agnieszka Zapasnik, Pascaline Aimee Uwineza, Edyta Ksieniewicz-Wozniak, Marta Modrzewska, Agnieszka Waskiewicz
Summary: This review summarizes the latest research on the toxic secondary metabolites of Fusarium in maize, including modified forms of mycotoxins, the research progress on the health effects, and the development of biological methods to eliminate the presence of mycotoxins.
Article
Environmental Sciences
Abdul Qader, Kanwal Rehman, Muhammad Sajid Hamid Akash
Summary: This study investigated the impairment of lipid metabolism induced by lead (Pb) and its amelioration through plant-based therapeutic interventions. Pb-induced hepatotoxicity disrupted the normal levels of antioxidant enzymes, leading to lipid peroxidation. Additionally, Pb toxicity altered the regulation of hormones involved in the synthesis of HMG-CoA reductase, resulting in abnormal levels of serum cholesterol and other lipid molecules. The administration of resveratrol effectively treated Pb toxicity. Overall, this study demonstrated the therapeutic effect of resveratrol in improving Pb-induced lipid metabolism impairment by using vitamin C as a standard intervention.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Plant Sciences
Ozlem Gulmez, Deniz Tiryaki, Okkes Atici, Ozlem Baris
Summary: The effect of Alternaria alternata (OG14) isolated from a rock lichen (Xanthoria sp.) on alleviating boron stress in wheat was studied. The fungus was found to tolerate boric acid (BA) concentrations up to 1 M, beyond which its colony development decreased. BA application significantly increased the contents of boron, magnesium, phosphorus, potassium, and iron in wheat seedlings but the treatment with fungus + BA decreased these element contents. BA application resulted in increased levels of reactive oxygen species and lipid peroxidation in the seedlings, while fungal inoculation under the same BA conditions decreased these parameters. It was observed that A. alternata treatment mitigates the negative effects of B stress on wheat seedlings by reducing ROS, LPO, B content, increasing enzymatic and non-enzymatic antioxidants, and improving root and shoot length.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Fisheries
Hongjian Lu, Zhengxi Wang, Yuwei Ding, Xue Feng, Chunxian Zhao, Linghan Chen, Weizhi Yao, Dan Xi, Mei Fu
Summary: In this study, it was found that injection of Calcein (CAL) could induce a strong oxidative stress response in juvenile silver carp. The severity of oxidative stress was correlated with the injection dose and time after injection. Higher CAL doses could lead to greater toxicity in the fish. When using CAL for fluorescent labeling, the injection dose should be restricted to 25 mg/kg or less and the injected fish should be reared for at least 16 days.
Article
Multidisciplinary Sciences
Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-Ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, Andre Santos Dias Mourao, Andreas Linkermann, Edward K. Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A. Pratt, Marcus Conrad
Summary: A study identifies the anti-ferroptotic function of vitamin K and reveals FSP1 as the enzyme mediating warfarin-resistant vitamin K reduction, highlighting the importance of FSP1 in protecting cells against lipid peroxidation and ferroptosis.
Article
Cell Biology
Chao Xu, Su Ni, Nanwei Xu, Guangrong Yin, Yunyuan Yu, Baojun Zhou, Gongyin Zhao, Liangliang Wang, Ruixia Zhu, Shijie Jiang, Yuji Wang
Summary: This study found that Theaflavin-3,3'-digallate (TF3) significantly inhibits chondrocyte ferroptosis by activating the Nrf2/Gpx4 signaling pathway, indicating its potential as a therapeutic supplement for osteoarthritis (OA) treatment.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2022)
Article
Agriculture, Dairy & Animal Science
Iveta Placha, Kristina Bacova, Karin Zitterl-Eglseer, Andrea Laukova, Lubica Chrastinova, Michaela Madarova, Rudolf Zitnan, Gabriela Strkolcova
Summary: The study found that thymol had significant effects on gut health and immune response in rabbits, particularly in terms of villi height, phagocytic activity, and lactic acid bacteria levels. These effects were observed even after thymol was withdrawn, demonstrating its biological properties and positive impact on rabbit health.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2022)
Article
Agriculture, Dairy & Animal Science
Monika Pogany Simonova, Andrea Laukova, Lubica Chrastinova, Anna Kandricakova, Jana Scerbova, Viola Strompfova, Sona Gancarcikova, Iveta Placha, Rudolf Zitnan
Summary: This study showed that the use of enterocins EntM and durancin EntED26E/7 in rabbit nutrition can improve serum biochemistry, phagocytic activity, and jejunal morphometry. Both enterocins positively influenced tested serum parameters, with durancin EntED26E/7 having a significant impact.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2022)
Article
Infectious Diseases
Andrea Laukova, Igor Stojanov, Jasna Prodanov-Radulovic, Marian Madar, Valentina Fockova, Jana Scerbova, Lubomi Gresakova, Monika Pogany Simonova
Summary: This study investigates the increasing incidence of methicillin-resistant Staphylococcus pseudintermedius strains in dogs, which have become the most common cause of canine skin lesions. The susceptibility of these strains to bacteriocins, specifically gallidermin, is determined, providing a new opportunity for preventing/eliminating infection caused by these multi-resistant strains.
MICROBIAL DRUG RESISTANCE
(2022)
Article
Biotechnology & Applied Microbiology
Andrea Laukova, Lenka Micenkova, Ivana Kubasova, Eva Bino, Anna Kandricakova, Iveta Placha, Gabriela Strkolcova, Branislav Galik, Anton Kovacik, Marko Halo, Monika Pogany Simonova
Summary: This study tested the application of a wild strain of bacteria producing bacteriocin in horses. The results showed that the strain can colonize the horses' gastrointestinal tract and have an effect on parasite eggs.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Agriculture, Dairy & Animal Science
Grzegorz Skiba, Stanislawa Raj, Monika Sobol, Pawel Kowalczyk, Marcin Barszcz, Marcin Taciak, Anna Tusnio, Klaudia Cobanova, L'ubomira Gresakova, Eugeniusz Ryszard Grela
Summary: The effects of zinc and fibre source in piglets' diet on bone mineral content, density, and strength parameters were investigated. The diet with zinc glycinate significantly increased bone mineral content and density, as well as maximum and elastic strength and bone stiffness. The type of fibre in the diet only affected the mass of the femur. Digestible zinc intake and zinc content in the blood serum were positively correlated with the measured bone parameters.
Article
Microbiology
Michaela Komaromyova, Daniel Petric, Katarina Kuckova, Dominika Batt'anyi, Michal Babjak, Michaela Urda Dolinska, Alzbeta Konigova, Daniel Barcak, Emilia Dvoroznakova, Klaudia Cobanova, Zora Varadyova, Marian Varady
Summary: Our study analyzed the parasitological status, antibody responses, and antioxidant parameters of lambs infected with gastrointestinal nematode during the consumption of sainfoin pellets. The results showed that sainfoin pellet treatment reduced the number of eggs and abomasal worms, and had an impact on antibody response and blood antioxidant enzyme activity, thus improving the lambs' resistance.
Article
Agronomy
Katarina Tokarcikova, Klaudia Cobanova, Margareta Takacsova, Marcin Barszcz, Marcin Taciak, Anna Tusnio, L'ubomira Gresakova
Summary: The study examined how the intake of Zn and fibre sources affected the apparent digestibility and solubility of trace elements in the small intestines of 40-day-old piglets. Results showed that feed supplementation with potato fibre affected the digestibility and solubility of all trace elements, while intake of Zn glycinate decreased Zn absorption and affected the solubility of other trace elements. The combination of in vitro and in vivo methods can predict trace mineral absorption.
Article
Biotechnology & Applied Microbiology
Andrea Laukova, L'ubica Chrastinova, Lenka Micenkova, Eva Bino, Ivana Kubasova, Anna Kandricakova, Sona Gancarcikova, Iveta Placha, Monika Holodova, L'ubomira Gresakova, Zuzana Formelova, Monika Pogany Simonova
Summary: Young rabbits are susceptible to gastrointestinal diseases caused by bacteria. Enterococcus hirae can be associated with diseases. But enterocins produced by some enterococcal species can prevent/reduce this problem. The interaction of enterocin M with a biofilm-forming, autochthonous E. hirae Kr8(+) strain was tested in rabbits to assess enterocin potential in vivo. The results showed that enterocin M can reduce the abundance of Kr8(+) and increase phagocytic activity in rabbits.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2022)
Editorial Material
Agriculture, Dairy & Animal Science
Iveta Placha, Monika Pogany Simonova, Andrea Laukova
Editorial Material
Veterinary Sciences
Iveta Placha, Francesco Gai, Monika Pogany Simonova
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agronomy
Dobroslava Bujnakova, Katarina Kuckova, Zora Varadyova, Iveta Placha, Viola Strompfova, Jan Bohm, Lenka Micenkova, Klaudia Cobanova
Summary: The purpose of this experiment was to investigate the effects of feed supplementation with organic zinc and/or a medicinal plants mixture on the composition and enzymatic activity of intestinal microflora, as well as on the integrity of the duodenal and jejunal barriers in lambs. The results showed that the dietary intake of organic zinc and/or medicinal plants did not alter the diversity of intestinal bacteria in growing lambs, but significantly influenced the activity of bacterial enzymes. The combination of zinc and herbs demonstrated the potential to regulate intestinal permeability by increasing the level of tight junction proteins in the jejunal mucosa.
