Article
Engineering, Environmental
Klara Rusevova Crincoli, Scott G. Huling
Summary: For the first time, the fate of radicals in heterogeneous chemical oxidation treatment systems was studied, with UV-AHP and UV-APS generating center dot OH and SO4 center dot- radicals that impact treatment efficiency. The higher scavenging rates of center dot OH by alumina and aqueous/solid phase constituents, compared to SO4 center dot-, contributed to lower treatment efficiency in the UV-AHP system. The cost assessment based on overall treatment efficiency showed higher specific cost for treating the probe compound with UV-AHP due to its lower treatment efficiency compared to UV-APS.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Organic
Chris M. Seong, Annabel Q. Ansel, Courtney C. Roberts
Summary: The construction of alkyl-alkyl bonds is an important tool in organic synthesis. In this study, a photocatalytic coupling of carboxylic acids to form bibenzyls was reported. The redox-opposite relationship between carboxylic acids and their redox-active esters was explored for the first time, providing mechanistic insights and potential applications in catalysis.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Hao Zuo, Chen Zhang, Yang Zhang, Dawen Niu
Summary: A simple and general method for fully unprotected, stereoselective glycosylation of carboxylic acids was developed using bench-stable allyl glycosyl sulfones as donors. The reaction, conducted under basic conditions, showed high efficiencies and selectivities. Both the donor activation stage and the glycosidic bond forming stage were compatible with free hydroxyl groups.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Viet D. Nguyen, Graham C. Haug, Samuel G. Greco, Ramon Trevino, Guna B. Karki, Hadi D. Arman, Oleg V. Larionov
Summary: A direct decarboxylative sulfinylation reaction was developed, enabling the conversion of carboxylic acids to sulfoxides. This reaction improves the structural diversity of synthetically accessible sulfoxides.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Energy & Fuels
Shiling Fan, Hao Li
Summary: This work comprehensively reviews the latest developments in the hydrosilylation of biomass, focusing on noble and non-noble metal catalysts. The study discusses the regulation of catalyst activity, selectivity, and stability in biomass derivatives hydrosilylation through different ligand structures and support microstructures. Additionally, various metal catalyzed hydrosilylation mechanisms are discussed in depth.
Article
Food Science & Technology
David Fonseca Hernandez, Luis Mojica, Mark A. Berhow, Korey Brownstein, Eugenia Lugo Cervantes, Elvira Gonzalez de Mejia
Summary: This study aimed to determine the antioxidant and anti-inflammatory potentials of crude extract (CE) and phenolic-enriched extract (PHE) obtained from the seed coats (SCs) of black bean (BB) and pinto bean (PB) varieties. The results showed that PHE exhibited high antioxidant and radical scavenging capacities, with a strong correlation with total phenolic content (TPC). PHE also exhibited strong inhibitory effects on COX-2 and iNOS, indicating the potential of phenolic compounds in the seed coats of black and pinto beans as antioxidants and anti-inflammatory agents.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Chemistry, Organic
Qiuling Song, Fumei Ke, Changjiang Yu, Xin Li, Heyun Sheng
Summary: A convenient method for synthesizing fluorine-containing heterocyclic compounds was developed, involving copper-catalyzed free radical addition and molecular lactone exchange of alkynol and ethyl bromodifluoroacetate. This method offers easy availability of raw materials, good stereochemical selectivity, and simple operation. It also allows for the synthesis of valuable tetrasubstituted E-configurated alkenes and various vinyl C-Br bonds and difluoromethylene-containing functionalized heterocycles.
Article
Environmental Sciences
Bartlomiej Witkowski, Jian Chi, Priyanka Jain, Kacper Blaziak, Tomasz Gierczak
Summary: This study measured the reaction rate coefficients of hydroxyl radicals with various forms of aliphatic carboxylic acids, identifying significant pH dependence in only some acids. By optimizing structure-activity relationship parameters, accurate prediction of kOH values for aliphatic carboxylic acids in a specific temperature range was achieved. The developed SAR model was validated against experimental measurements from this study and literature data.
ATMOSPHERIC ENVIRONMENT
(2021)
Article
Chemistry, Organic
Wen-Hui Bao, Xuesong Wu
Summary: A visible-light-driven deoxygenative cross-coupling reaction of alcohols with sulfonyl oxime ethers has been developed using xanthate salts as alcohol-activating reagents. By convenient generation and direct photoexcitation of xanthate anions, a broad range of alcohols, including primary ones, can efficiently undergo this transformation to yield diverse oxime ethers and derivatives. This one-pot protocol offers mild conditions, broad substrate scope, and late-stage applicability without the need for external photocatalysts or electron donor-acceptor complex formation.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Food Science & Technology
Jiahuan Dong, Lijun Ping, Qinggang Xie, Deyu Liu, Li Zhao, Smith Etareri Evivie, Zhongjiang Wang, Bailiang Li, Guicheng Huo
Summary: The study found that Lactobacillus plantarum KLDS 1.0386 has strong antioxidant capacity and can alleviate LPS-induced acute liver injury. This strain demonstrates excellent adhesion and anti-inflammatory properties, significantly reducing hepatic tissue injury and pro-inflammatory cytokine levels.
Article
Engineering, Environmental
Wei Hong, Yan Liu, Xinxin Jiang, Chenguang An, Tianle Zhu, Ye Sun, Haining Wang, Fangxia Shen, Xiang Li
Summary: Appropriate introduction of alkali metal can improve the formation ability of hydroxyl radicals (center dot OH) during catalytic ozonation process, leading to enhanced toluene degradation. The introduction of 5.9wt% K+ resulted in the formation of the highest amount of center dot OH and exhibited excellent catalytic activity and selectivity. The deactivated catalyst can be regenerated through water washing and heat treatment.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Organic
Joseph M. Anderson, Nicholas D. Measom, John A. . Murphy, Darren L. Poole
Summary: Here, we present a decarboxylative Minisci hetero-arylation study at the bridge positions. Through a simple and photocatalyst-free process, free bridge carboxylic acids are directly coupled with nonprefunctionalized heteroarenes to yield polysubstituted BCP and oBCH derivatives in high yields. Furthermore, the impact of the BCP core on the physicochemical properties of a representative example compared to its all-aromatic ortho- and meta-substituted analogues is evaluated.
Article
Chemistry, Organic
Dangui Wang, Wentao Zhang, Xunbo Lu, Hongwei Zhou, Fangrui Zhong
Summary: Novel cinchona alkaloid derived iodide catalysts were developed for the enantioselective oxidative alpha-amination of 2-oxindoles, providing various functionalized spiropyrrolidine oxindoles in high yields and with good enantioselectivities. This iodide/ROOH catalytic system features a one-step synthesis of a catalyst with multiple functionalities, ease of operation, and good scalability, thereby enriching the repertoire of iodide catalysis for enantioselective oxidative coupling reactions.
Article
Chemistry, Multidisciplinary
Linhua Xu, Qishuai Li, Dongwei Li, Xin Zhou, Ni Song, Peng Wang, Ming Li
Summary: A direct oxidative radical decarboxylative cyanomethylation of carboxylic acids using 3-azido-2-methylbut-3-en-2-ol as the carbon-centered radical acceptor is described. The method is applicable to various α-amino acids, α-oxy acids, α-keto acids, pentofuranuronic acids, and hexopyranuronic acids. Mechanistic investigations suggest the involvement of a radical process. This work provides a potential approach to synthesize biologically relevant β-amino acids, 5-deoxy-hexofuranose, and 6-deoxy-heptose constructs.
CHINESE JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Channa Basappa Vagish, Achutha Dileep Kumar, Karthik Kumara, Hamse Kameshwar Vivek, Nagamallu Renuka, Neratur Krishnappagowda Lokanath, Kariyappa Ajay Kumar
Summary: Oxidative stress is a major factor in neurogenerative diseases, and the search for effective antioxidants to combat this stress is crucial. The synthesis of novel antioxidants in this study showed promising results in reducing oxidative stress in the body by enhancing superoxide dismutase activity. Further research on these antioxidant molecules may lead to new treatments for oxidative stress-related diseases.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2021)
