Article
Engineering, Environmental
Lindsay Jasperse, Richard T. Di Giulio, Nishad Jayasundara
Summary: This study investigates the bioenergetic costs of polycyclic aromatic hydrocarbons (PAHs) resistance among Atlantic killifish. The results show that metabolic rates differ between offspring of PAH-resistant fish and reference fish, particularly at the juvenile life stage. The study also suggests that killifish from remediated sites may be more sensitive to PAH exposure compared to those from nonremediated sites, indicating a loss of PAH tolerance following relaxed selection.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Luisa Albarano, Ilaria De Rosa, Ilaria Santaniello, Maria Montuori, Sara Serafini, Maria Toscanesi, Marco Trifuoggi, Giusy Lofrano, Marco Guida, Giovanni Libralato
Summary: This research examined the short-term effects (48 hours of exposure) of polycyclic aromatic hydrocarbons (PAHs) mixtures on the nauplii and adult of Artemia franciscana. The study found additive or synergic effects for most PAHs combinations, except for naphthalene + phenanthrene which showed an antagonistic effect. The expression level of five stress-response genes in Artemia was also impacted by the PAHs mixtures.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Luisa Albarano, Sara Serafini, Maria Toscanesi, Marco Trifuoggi, Valerio Zupo, Maria Costantini, Davide A. L. Vignati, Marco Guida, Giovanni Libralato
Summary: The study investigates the effects of polycyclic aromatic hydrocarbons (PAHs) on Artemia franciscana and finds that fluoranthene (FLT) is the most toxic substance, with all toxicants able to alter the gene expression of nine genes. The research has significant implications for the assessment of contaminated sediment and understanding molecular pathways in crustaceans.
Article
Environmental Sciences
Oumayma Kahla, Sondes Melliti Ben Garali, Fatma Karray, Manel Ben Abdallah, Najwa Kallel, Najla Mhiri, Hatem Zaghden, Badreddine Barhoumi, Olivier Pringault, Marianne Quemeneur, Marc Tedetti, Sami Sayadi, Asma Sakka Hlaili
Summary: The efficiency of a benthic diatom-associated bacteria in removing BaP and Flt was investigated in this study. Results showed a co-metabolic synergy between microalgae and associated bacteria in biodegrading PAHs, suggesting their potential application in the bioremediation of contaminated sites.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Biochemistry & Molecular Biology
Bozena Bukowska, Katarzyna Mokra, Jaromir Michalowicz
Summary: Benzo[a]pyrene (B[a]P) is a representative polycyclic aromatic hydrocarbon (PAH) that is commonly found in the environment and human surroundings. It has been shown to have toxic effects on DNA, reproduction, neurology, and development. The metabolism of B[a]P is mediated by cytochrome P450 (CYP P450) and its polymorphism determines the sensitivity to B[a]P. Additionally, B[a]P may facilitate the replication of viruses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Toxicology
Neelakanteswar Aluru, Jan Engelhardt
Summary: Exposure to a dioxin-like polychlorinated biphenyl during preconception affects DNA methylation and gene expression in the testis of zebrafish, which may contribute to spermatogenic defects.
TOXICOLOGICAL SCIENCES
(2022)
Article
Environmental Sciences
Lauren K. Redfern, Nishad Jayasundara, David R. Singleton, Richard T. Di Giulio, James Carlson, Susan J. Sumner, Claudia K. Gunsch
Summary: The study found that alterations in gut microbiomes and metabolites play a critical role in the process of evolving resistance to polycyclic aromatic hydrocarbons in killifish. The composition of gut microbiomes in resistant fish differs from that in sediments, and resistant fish exhibit significant changes in metabolites.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biochemistry & Molecular Biology
Krystian Mokrzynski, Grzegorz Szewczyk, Tadeusz Sarna
Summary: This study measured the quantum yield and action spectra of singlet oxygen photogeneration by benzopyrenes and their ability to generate superoxide anion. The results revealed the photochemical activity of benzopyrenes in producing singlet oxygen and superoxide anion. Furthermore, the cytotoxicity of benzopyrenes was demonstrated in skin model cells, with concentration-dependent and light-dependent effects, leading to damage to cell mitochondria and increased levels of intracellular reactive oxygen species.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2023)
Article
Chemistry, Inorganic & Nuclear
Huimin Zhong, Cong Jiang, Jiahui Zou, Guancheng Zhu, Yanyan Huang
Summary: In this study, CeO2-based porous carbonaceous frameworks (CeO2 PCFs) were used as antioxidant nanozymes to scavenge reactive oxygen species and absorb benzo[a]pyrene. CeO2 PCFs exhibited excellent superoxide dismutase-like and catalase-like activity, effectively eliminating superoxide radical, hydroxyl radical, and hydrogen peroxide. The 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) free radical scavenging assay confirmed the free radical scavenging ability of CeO2 PCFs. Furthermore, CeO2 PCFs with large surface area and porous structure efficiently adsorbed benzo[a]pyrene. The designed CeO2 PCFs can serve as new antioxidant nanozymes for scavenging reactive oxygen species and adsorbing polycyclic aromatic hydrocarbons (PAHs).
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Jingnan Jin, Yahui Shi, Baozhong Zhang, Dongjin Wan, Qingye Zhang, Ying Li
Summary: In this study, a BaP-degrading strain Pannonibacter sp. JPA3 was isolated from oil well production water, which could remove 80% of BaP at an initial concentration of 100 mg L-1 after 35 days of culture. The metabolites BaP-4,5-dihydrodiol, BaP-4,5-epoxide, 5-hydroxychrysene, and 2-hydroxy-1-naphthoic acid were identified in the biodegradation process. A dioxygenase model was built and molecular docking was performed to investigate the interaction mechanism between BaP and dioxygenase. A hypothesis for the progressive degradation mechanism of BaP by this strain was proposed based on the identification of downstream metabolites. In conclusion, this study provided an efficient BaP degrader and a comprehensive reference for the study of degradation mechanisms at the molecular level.
Article
Environmental Sciences
In Joon Hwang, Hea Ja Baek
Summary: In this study, we found that PCB126 has estrogenic activity in oocyte maturation in Tridentiger obscurus. PCB126 can inhibit testosterone production and increase estradiol production. Additionally, PCB126 can inhibit germinal vesicle breakdown.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Environmental Sciences
Suyane Silva Moreira, Leonardo Cesar de Lima Inocencio, Barbara Campos Jorge, Ana Carolina Casali Reis, Hamilton Hisano, Arielle Cristina Arena
Summary: Studies show that low doses of the polycyclic aromatic hydrocarbon Benzo(a)Pyrene (BaP) can have teratogenic effects and impact reproductive and developmental performance in pregnant rats and fetuses, leading to anomalies in renal size and degree of fetal ossification.
ENVIRONMENTAL TOXICOLOGY
(2021)
Article
Environmental Sciences
Yun Luo, Baoqin Zhang, Ningbo Geng, Shuai Sun, Xiaoyao Song, Jiping Chen, Haijun Zhang
Summary: The study investigated the toxicological effects of chlorinated polycyclic aromatic hydrocarbons (Cl-PAHs) on human L02 hepatocytes, finding that 6-Cl-B[a]P exhibited stronger toxicity, metabolomic perturbation, and oxidative stress compared to B[a]P. Additionally, 6-Cl-B[a]P caused a wider disruption to metabolic pathways and inhibited mitochondrial electron transport chain activities more significantly than B[a]P. Both compounds also disturbed nucleotide metabolism, glycerophospholipid metabolism, and amino acid metabolism in L02 cells.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biotechnology & Applied Microbiology
Mercedes Quintanilla-Mena, Julio Vega-Arreguin, Marcela Del Rio-Garcia, Victoria Patino-Suarez, Santy Peraza-Echeverria, Carlos Puch-Hau
Summary: The study investigated the effects of BaP on the gut microbiome of Oreochromis niloticus. Dysbiosis was observed at 24 hours post-injection, followed by a slight recovery at 72 hours and stabilization at 120 hours. The gut microbiome played a significant role in PAH degradation mainly at 24 hours post-injection.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Environmental Sciences
Barbara Campos Jorge, Ana Carolina Casali Reis, Erika Tissiana Sterde, Paola da Silva Balin, Wellerson Rodrigo Scarano, Hamilton Hisano, Arielle Cristina Arena
Summary: BaP exposure during the prepubertal period negatively impacted the reproductive parameters in adult male rats, leading to compromised copulatory behavior, reduced sperm quality and quantity, and histopathological changes in testicular tissue. A comprehensive risk assessment of prepubertal BaP exposure is necessary to understand its long-term effects on male reproductive health.
Article
Evolutionary Biology
Steven P. Brady, Emily Monosson, Cole Matson, John W. Bickham
EVOLUTIONARY APPLICATIONS
(2019)
Editorial Material
Marine & Freshwater Biology
Elias M. Oziolor, T. Ryan Gregory, John W. Bickham, Judy St Leger, Cole W. Matson
MARINE MAMMAL SCIENCE
(2019)
Article
Multidisciplinary Sciences
Elias M. Oziolor, Noah M. Reid, Sivan Yair, Kristin M. Lee, Sarah Guberman VerPloeg, Peter C. Bruns, Joseph R. Shaw, Andrew Whitehead, Cole W. Matson
Article
Environmental Sciences
Grace E. Sutherland, Marco E. Franco, Cole W. Matson, Ramon Lavado
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2020)
Article
Engineering, Environmental
Astrid Avellan, Marie Simonin, Steven M. Anderson, Nicholas K. Geitner, Nathan Bossa, Eleanor Spielman-Sun, Emily S. Bernhardt, Benjamin T. Castellon, Benjamin P. Colman, Jane L. Cooper, Mengchi Ho, Michael F. Hochella, Heileen Hsu-Kim, Sayako Inoue, Ryan S. King, Stephanie Laughton, Cole W. Matson, Brittany G. Perrotta, Curtis J. Richardson, Jason M. Unrine, Mark R. Wiesner, Gregory Lowry
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2020)
Article
Engineering, Environmental
Brittany G. Perrotta, Marie Simonin, Jeffrey A. Back, Steven M. Anderson, Astrid Avellan, Christina M. Bergemann, Benjamin T. Castellon, Benjamin P. Colman, Gregory Lowry, Cole W. Matson, Emily S. Bernhardt, Ryan S. King
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2020)
Article
Environmental Sciences
Christine M. Custer, Thomas W. Custer, Paul M. Dummer, Sandra Schultz, Chi Yen Tseng, Natalie Karouna-Renier, Cole W. Matson
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2020)
Article
Environmental Sciences
Beth Polidoro, Cole W. Matson, Mary Ann Ottinger, D. Abigail Renegar, Isabel C. Romero, Daniel Schlenk, John Pierce Wise, Jesus Beltran Gonzalez, Peter Bruns, Kent Carpenter, Dorka Cobian Rojas, Tracy K. Collier, Thomas F. Duda, Patricia Gonzalez-Diaz, Richard Di Giulio, R. Dean Grubbs, J. Christopher Haney, John P. Incardona, Guillermo Horta-Puga, Christi Linardich, Jon A. Moore, Daniel Pech, Susana Perera Valderrama, Gina M. Ralph, Kyle Strongin, Amy H. Ringwood, Bernd Wursig
Summary: Understanding the impact of petrochemicals and other stressors on marine biodiversity is crucial for effective management. A trait-based assessment can help rank species vulnerabilities to petrochemical activities, allowing for better prioritization of species, habitats, and ecosystems for management, restoration, and recovery efforts. The developed framework can be applied to a wide range of species and regions, with recommendations for specific petrochemical exposure scenarios.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Marine & Freshwater Biology
Marco E. Franco, Alejandro J. Ramirez, Karla M. Johanning, Cole W. Matson, Ramon Lavado
Summary: Chronic exposure to pollution may lead to evolutionary adaptations in populations, affecting the cellular and physiological mechanisms of defense against toxins. This study compares two populations of Gulf killifish with different exposure histories, investigating potential differences in the biotransformation of benzo[a]pyrene (BaP) and assessing the applicability of new approach methodologies (NAMs) for biotransformation assessments. The pollution-adapted population displayed lower CYP1A activity and intrinsic clearance rates compared to the non-adapted population. The in vitro and in vivo approaches identified similar metabolites, but population differences were observed for specific metabolites in the bile of pollution-adapted fish. This research enhances our understanding of the evolutionary adaptation of F. grandis in heavily polluted environments and highlights the importance of considering evolutionary history in biotransformation assessments.
AQUATIC TOXICOLOGY
(2022)
Article
Environmental Sciences
Marco E. Franco, Karla Johanning, Cole W. Matson, Ramon Lavado
Summary: Anthropogenic pollution can lead to evolutionary adaptations in organisms, affecting their metabolism of pollutants. This study found that pollution-adapted Gulf killifish populations had lower hepatic clearance of polycyclic aromatic hydrocarbons (PAHs), with differences between sexes and populations, indicating the significance of exposure and evolutionary history in shaping responses to pollution.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Megan Woodyard, Beth A. Polidoro, Cole W. Matson, Ryan A. McManamay, Steven Saul, Kent E. Carpenter, Tracy K. Collier, Richard Di Giulio, R. Dean Grubbs, Christi Linardich, Jon A. Moore, Isabel C. Romero, Daniel Schlenk, Kyle Strongin
Summary: This article introduces a trait-based petrochemical vulnerability index for assessing the sensitivity and resilience of marine fish populations in the Gulf of Mexico to oil and gas activities. Based on current knowledge, marine fish species with high vulnerability scores are primarily found in areas of high petrochemical activity, with low reproductive turnover rates and highly specialized diet and habitat requirements.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Chi Yen Tseng, Christine M. Custer, Thomas W. Custer, Paul M. Dummer, Natalie Karouna-Renier, Cole W. Matson
Summary: A multi-omics approach was used to assess the effects of chemical mixtures in the Maumee River on biological responses and functions. The study identified altered gene expression related to cell growth and cell cycle regulation, as well as upregulation of lipogenesis genes. The study highlights the potential health risks associated with increased pollutant concentrations in the river.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Environmental
Brittany G. Perrotta, Marie Simonin, Benjamin P. Colman, Steven M. Anderson, Ethan Baruch, Benjamin T. Castellon, Cole W. Matson, Emily S. Bernhardt, Ryan S. King
Summary: The chronic exposure of freshwater ecosystems to engineered nanoparticles (NPs) shows negative effects on insect emergence and insect-mediated contaminant flux to riparian spiders. Copper and gold NPs lead to a significant decrease in insect abundance and an increase in metal transportation to riparian spiders. This study reveals the transfer of NPs from aquatic to terrestrial ecosystems and the adverse impact on insect and spider populations.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
S. Rebekah Burket, Moncie Wright, Leanne F. Baker, C. Kevin Chambliss, Ryan S. King, Cole W. Matson, Bryan W. Brooks
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Chemistry, Multidisciplinary
Nicholas K. Geitner, Christine Ogilvie Hendren, Geert Cornelis, Ralf Kaegi, Jamie R. Lead, Gregory V. Lowry, Iseult Lynch, Bernd Nowack, Elijah Petersen, Emily Bernhardt, Scott Brown, Wei Chen, Camille de Garidel-Thoron, Jaydee Hanson, Stacey Harper, Kim Jones, Frank von der Kammer, Alan Kennedy, Justin Kidd, Cole Matson, Chris D. Metcalfe, Joel Pedersen, Willie J. G. M. Peijnenburg, Joris T. K. Quik, Sonia M. Rodrigues, Jerome Rose, Phil Sayre, Marie Simonin, Claus Svendsen, Robert Tanguay, Nathalie Tefenkji, Tom van Teunenbroek, Gregory Thies, Yuan Tian, Jacelyn Rice, Amalia Turner, Jie Liu, Jason Unrine, Marina Vance, Jason C. White, Mark R. Wiesner
ENVIRONMENTAL SCIENCE-NANO
(2020)