Article
Materials Science, Ceramics
Michal Hicak, L'ubomir Medvecky, Miroslav Hnatko, Radoslava Stulajterova, Maria Giretova, Monika Tatarkova, Zoltan Lences, Pavol Sajgalik
Summary: The addition of highly porous silicon nitride/alpha-tricalcium phosphate microgranules improved the tetracalcium phosphate/monetite biocement, serving as a potential carrier for drug release. By adjusting the amount of drug-infiltrated ceramic granules, the total drug release time can be modified.
INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
De-Xiang Zhang, Terence Tieu, Lars Esser, Marcin Wojnilowicz, Chieh-Hua Lee, Anna Cifuentes-Rius, Helmut Thissen, Nicolas H. Voelcker
Summary: In this study, a method for modifying the internal and external surfaces of porous silicon nanoparticles (pSiNPs) was developed. The modified pSiNPs showed excellent colloidal stability in a cell culture medium and the drug release kinetics could be fine-tuned by the combination of internal and external surface modifications. Moreover, the drug-loaded and peptide-functionalized nanoparticles exhibited enhanced cytotoxicity against prostate carcinoma cells.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Wei Duan, Xingyue Liu, Jingwen Zhao, Yongke Zheng, Jianmin Wu
Summary: This study demonstrates that surface modification of porous silicon with polydopamine can endow the classical drug carrier with a significant photothermal effect for advanced antibacterial therapy and wound disinfection. The carrier can release antibacterial substances and drugs under multiple stimuli, exhibiting amplified, broad-spectrum, and synergistic antibacterial effect. In vivo experiments show efficient bacterial ablation and wound healing with negligible side effects.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Pharmacology & Pharmacy
Carolina Medina-Montano, Ignacio Rivero Berti, Rocio C. Gambaro, Maria Jose Limeres, Malin Svensson, Gisel Padula, Cecilia Y. Chain, Jose Sebastian Cisneros, Guillermo R. Castro, Stephan Grabbe, Matthias Bros, Stephan Gehring, German A. Islan, Maximiliano L. Cacicedo
Summary: Nanostructured lipid carriers are a reliable platform for encapsulating and releasing dexamethasone, which showed good tolerance by non-parenchymal liver cells and preserved its anti-inflammatory activity, suggesting its potential for treating pathologies associated with chronic liver inflammation.
Article
Pharmacology & Pharmacy
Eva Kickova, Stefano Salmaso, Francesca Mastrotto, Paolo Caliceti, Arto Urtti
Summary: The pullulan-dexamethasone conjugates can self-assemble into nanoparticles with stable characteristics, slow drug release, non-toxicity in cells, cellular association, and endosomal localization. These features make them potentially successful for intravitreal drug delivery.
Article
Engineering, Biomedical
Yufei Xue, Hua Bai, Bo Peng, Terence Tieu, Jiamin Jiang, Shiping Hao, Panpan Li, Mark Richardson, Jonathan Baell, Helmut Thissen, Anna Cifuentes, Lin Li, Nicolas H. Voelcker
Summary: This study describes a step-changing solution to the challenge of controlled drug release using porous silicon nanoparticles (pSiNPs). The covalent conjugation of different stimulus-cleavable linkers and an anticancer drug to pSiNPs resulted in improved stability and highly controlled release behavior, leading to excellent tumor growth inhibition.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Pharmacology & Pharmacy
Nazia Tabassum, Maria Alba, Li Yan, Nicolas H. Voelcker
Summary: Porous silicon microneedles (pSi MNs) with controlled degradation, tunable porosity, and high mechanical stability are introduced for transdermal delivery of bioactive molecules. By changing the thickness of the porous layer, the biodegradability and mechanical properties of pSi MNs can be adjusted. pSi MNs can uniformly load both small and macromolecular drug molecules, and ex vivo experiments demonstrate their efficient transdermal delivery capability.
ADVANCED THERAPEUTICS
(2023)
Article
Pharmacology & Pharmacy
Candida A. Cisneros-Covarrubias, Cesar F. A. Gomez-Duran, Patricia Aguirre-Banuelos, Rosa Alejandra Hernandez-Esquivel, Gabriela Palestino
Summary: Thermally oxidized porous silicon particles with different particle and pore dimensions were synthesized and used as drug delivery systems for sustained release of tramadol hydrochloride. The study demonstrated that the size of the particles and pores can be controlled by adjusting the etching parameters, and different pore sizes of silicon particles have varying effects on the loading capacity and release profile of tramadol.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Biomedical
Yaoxuan Cui, Wei Duan, Yao Jin, Fangjie Wo, Fengna Xi, Jianmin Wu
Summary: In this study, a stimuli-responsive smart dressing for diabetic wound theranostics was developed using graphene quantum dots-decorated luminescent porous silicon. The nanomaterial exhibited enhanced peptide drug loading capacity and efficient fluorescence resonance energy transfer (FRET) effect for effective diabetic wound treatment. The smart dressing showed stimuli-responsive drug release behavior and significantly enhanced the healing of diabetic wounds in both in vitro and in vivo studies.
ACTA BIOMATERIALIA
(2021)
Article
Engineering, Biomedical
Yu Wang, Jiahui Guo, Zhiqiang Luo, Yingbo Shen, Jinglin Wang, Yunru Yu, Yuanjin Zhao
Summary: This study presents novel prolamin-assembled porous hydrogel microfibers for treating diabetes wounds. The microfibers were continuously generated using microfluidic spinning technology. The resulting hydrogel microfibers demonstrated good cell-affinity, effective drug release efficiency, and superior performance in treating diabetes wounds.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Biophysics
Mohammad Akrami-Hasan-Kohal, Mahnaz Eskandari, Atefeh Solouk
Summary: The study developed a sustained release formulation using dexamethasone sodium phosphate-loaded chitosan nanoparticles embedded in silk fibroin hydrogel. The scanning electron microscopy showed the prepared drug delivery system had a properly interconnected porous structure, indicating potential for drug delivery applications.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Biotechnology & Applied Microbiology
Huiyu Zheng, Cong Zhang, Guiting Liu, Rong Chen, Shaoyun Guo
Summary: The multi-layered drug delivery system shows potential for controlled release, but current technologies struggle with regulating the number of layers and layer-thickness ratio. In this study, layer-multiplying co-extrusion technology was used to modulate the layer-thickness ratio and expand its application. Results showed that reducing the thickness of the PCL-MPT layer increased the release rate of metoprolol. Additionally, sustained release of metoprolol was achieved when the PCL-MPT/PEO composite was sealed by epoxy resin to eliminate the edge effect. Compression tests confirmed the potential of PCL-MPT/PEO composites as bone scaffolds.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
Raul Diaz-Salmeron, Balthazar Toussaint, Nicolas Huang, Etienne Bourgeois Ducournau, Gabriel Alviset, Sophie Goulay Dufay, Herve Hillaireau, Amelie Dufay Wojcicki, Vincent Boudy
Summary: Oral lichen planus is a chronic inflammatory disease treated with corticosteroid-containing formulations, but this administration route has limitations. The development of a new pharmaceutical formulation with mucoadhesive, sprayable, sustained, and controlled release properties may overcome these limitations for more effective treatment.
Article
Chemistry, Applied
Wan-Hua Lin, Sadhan C. Jana
Summary: This research investigates the porous structures of cellulose aerogel monoliths and microparticles, and evaluates the potential of cellulose aerogel microparticles in drug delivery. The aerogels exhibit high porosity, significant mesopores, and a high specific surface area. The porous architecture of the microparticles leads to a slower drug release compared to direct loading into aqueous medium.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Article
Pharmacology & Pharmacy
Jan Rozanc, Marko Zizek, Marko Milojevic, Uros Maver, Matjaz Finsgar
Summary: A multilayer bioactive coating based on CMC and DEX was successfully prepared, achieving controlled drug delivery and promoting osteogenic differentiation of stem cells. The coating significantly increased the hydrophilicity and surface roughness of stainless steel, while demonstrating good biocompatibility with various cell types.
Article
Optics
Chao Liu, Weiquan Su, Famei Wang, Xianli Li, Lin Yang, Tao Sun, Haiwei Mu, Paul K. Chu
JOURNAL OF MODERN OPTICS
(2019)
Article
Materials Science, Multidisciplinary
Haiwei Mu, Wenjing Xu, Chonghong Xu, Jingwei Lv, Wei Liu, Xianli Li, Qiang Liu, Chao Liu, Tao Sun, Paul K. Chu
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2019)
Article
Optics
Famei Wang, Zhijie Sun, Chunhong Xu, Lin Yang, Chao Liu, Tao Sun, Paul K. Chu
Article
Optics
Qiang Liu, Qingyu Liu, Yudan Sun, Wei Liu, Chao Liu, Qian Li, Tingting Lv, Tao Sun, Paul K. Chu
Article
Chemistry, Analytical
Thanh Qua Nguyen, Woo-Tae Park
SENSORS AND ACTUATORS B-CHEMICAL
(2020)
Article
Green & Sustainable Science & Technology
Le-Giang Tran, Woo-Tae Park
Summary: This study presents a pillar-based flow sensor that mimics the working principle of fish neuromasts for sensing water flow. The sensor fabrication process is simple and cost-effective, and it accurately measures hydrodynamic flow rate and direction.
INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING-GREEN TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Jingwei Lv, He Zhang, Chao Liu, Zao Yi, Famei Wang, Haiwei Mu, Xianli Li, Tao Sun, Paul K. Chu
Summary: This research systematically investigates the scattered radiation spectral features and field-enhanced interactions of gallium phosphide disks with forked slits at anapole modes, demonstrating a novel approach for near-field engineering by creating high-intensity hot spots inside the disk. The results show that opening the forked slits further enhances the electric field, allowing nearby molecules to access these hot spots directly, which has potential applications in electric field localization, nonlinear optics, and optical detection.
Article
Nanoscience & Nanotechnology
Helem B. Flores Marcial, Jiseob Choi, Donghwi Ham, Junghyun Kim, Pyeongho Jeong, Jinho Choi, Woo-Tae Park
Summary: Multiple lesions in the same vessel can complicate assessment and treatment, and in vitro platforms are needed for research. This study monitored thrombus formation in microchannels and found that the first stenosis could cause total occlusion.
MICRO AND NANO SYSTEMS LETTERS
(2022)
Article
Nanoscience & Nanotechnology
Ji-Seob Choi, Dong-Hwi Ham, Jung-Hyun Kim, Helem Betsua Flores Marcial, Pyeong-Ho Jeong, Jin-Ho Choi, Woo-Tae Park
Summary: In this study, a method to quantitatively analyze thrombus formation process through image analysis in an in vitro thrombus model with a circular cross section was presented. The image analysis helped visualize the thrombus formation process and calculate thrombus area, showing thrombus growth and embolus separation.
MICRO AND NANO SYSTEMS LETTERS
(2022)
Article
Green & Sustainable Science & Technology
Ji-Seob Choi, Jinhong Noh, Hongsoo Choi, Yong-Jin Yoon, Woo-Tae Park
Summary: This study aimed to develop a low-cost, micro-scale, and highly accurate dust sensor using semiconductor processes. The resonance frequency and mode shape of the sensor were measured and monitored using a Laser-Doppler-Vibrometer (LDV), and the resonance frequency shift was calculated based on the same mode shape. The experiment showed that the resonance frequency shift was influenced by the mass change of dust, and different vibration modes exhibited different trends.
INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING-GREEN TECHNOLOGY
(2023)
Review
Nanoscience & Nanotechnology
Dong-Hwi Ham, Ji-Seob Choi, Jin-Ho Choi, Woo-Tae Park
Summary: Thrombosis is a complex process with both protective and detrimental effects. The acute hemodynamic changes within the blood vessel lumen play a key role in thrombus formation. Microfluidic systems have emerged as a valuable tool for studying thrombosis due to their advantages of minimal sample requirements and rapid analysis capabilities. This mini review provides an overview of microfluidic systems designed for thrombosis analysis and discusses their potentials and limitations.
MICRO AND NANO SYSTEMS LETTERS
(2023)
Article
Nanoscience & Nanotechnology
Ji-Seob Choi, Woo-Tae Park
MICRO AND NANO SYSTEMS LETTERS
(2020)
Article
Nanoscience & Nanotechnology
Le-Giang Tran, Woo-Tae Park
MICRO AND NANO SYSTEMS LETTERS
(2020)
Proceedings Paper
Engineering, Electrical & Electronic
Le-Giang Tran, Dong-Hyun Joo, Woo-Tae Park
2019 20TH INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS & EUROSENSORS XXXIII (TRANSDUCERS & EUROSENSORS XXXIII)
(2019)
Proceedings Paper
Engineering, Electrical & Electronic
Le-Giang Tran, Thanh-Qua Nguyen, Woo-Tae Park
2019 IEEE 32ND INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS)
(2019)
Article
Chemistry, Physical
Qi-Wen Chen, Ze-Qing Guo, Jian-Ping Zhou
Summary: Multifunctional continuous solid solutions NFMTO-x were successfully synthesized via a one-step hydrothermal method by controlling the ratio of Mg and Fe. The NFMTO-x materials exhibited enhanced visible light response, effective adsorption and photocatalytic degradation of organic pollutants, CO2 methanation capability, and easy recyclability due to their magnetic properties. This research provides a significant multifunctional material for water purification.
APPLIED SURFACE SCIENCE
(2024)
Review
Chemistry, Physical
George E. Stan, Maziar Montazerian, Adam Shearer, Bryan W. Stuart, Francesco Baino, John C. Mauro, Jose M. F. Ferreira
Summary: Bioactive glasses have the ability to form strong bonds with tissues and release therapeutic ions. However, their biomechanical compatibility limits their use in load-bearing applications. The use of magnetron sputtering technology to fabricate BG coatings shows promise in improving their efficacy and potential for application.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Zhaoxuan Wang, Zhicheng Yan, Zhigang Qi, Yu Feng, Qi Chen, Ziqi Song, Meng Huang, Peng Jia, Ki Buem Kim, Weimin Wang
Summary: The corrosion behavior of Fe-60 and Fe-83 ribbons in 0.6 M NaCl was studied. Fe-60 exhibited a local corrosion mode and formed a stable passivation film with higher corrosion resistance, while Fe-83 showed a combination of local and global corrosion modes and had lower corrosion resistance. Controlling the precipitation of nanocrystalline phases and increasing the POx content in the passivation film significantly improved the corrosion resistance of Fe-based glassy alloys.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Hao-Kai Peng, Sheng-Yen Zheng, Wei-Ning Kao, Ting-Chieh Lai, Kai-Sheun Lee, Yung- Hsien Wu
Summary: This study investigates the effects of high energy/fluence proton radiation on the performance of HfZrOx-based FeFETs memory with different Zr content. The results show that the characteristics of FeFETs are influenced by proton radiation, and the extent of the influence depends on the Zr content. FeFETs with 50% Zr content exhibit minimal changes in memory window and demonstrate good endurance and retention performance.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Zongyi Yue, Guangyi Wang, Zengguang Huang, Sihua Zhong
Summary: In this study, AZO and ITO films were successfully tuned as excellent passivation layers for c-Si surfaces, achieving effective minority carrier lifetime and outstanding optical properties through the optimization of annealing temperature and interfacial silicon oxide.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Martin Hruska, Jan Kejzlar, Jaroslav Otta, Premysl Fitl, Michal Novotny, Jakub Cizek, Oksana Melikhova, Matej Micusik, Peter Machata, Martin Vrnata
Summary: This paper presents a detailed study on the hydrogen sensing capabilities of highly nanoporous black gold films. The films exhibit fast response and recovery times at low temperatures. Different levels of nanoporosity were prepared and tested to investigate the sensing properties, and it was found that nanoporous black gold is suitable for hydrogen sensing. The sensitivity of the film depends on its nanoporosity.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yupu Wang, Gaofeng Teng, Chun To Yiu, Junyi Zhu
Summary: In the study of BM-SCO and HSCO thin films, it was found that H vacancies tend to prefer sites near the external surface or oxygen vacancy channels (OVCs), while H interstitials prefer sites of oxygen on a layer that contains six-fold coordinated Co. These findings not only enrich the understanding of complex surface phenomena of defect formation but also provide an explanation for the reversibility during phase transformation.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Jiafeng Lu, Linping Teng, Qinxiao Zhai, Chunhua Wang, Matthieu Lancry, Ye Dai, Xianglong Zeng
Summary: In this study, we achieved full control of fiber nanograting orientation by manipulating laser polarization, and tailored space variant fiber nanogratings, which expanded the diversity in fiber nanograting engineering.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yibo Liu, Yujie Tao, Yue Liu, Qi Sun, Qinrong Lin, Kexin Kang, Qinghua Zhang, Qingjie Sun
Summary: This study investigates the wettability of the Ti-Cu-Fe multi-metal system, specifically the wetting behaviors of CuSi3 droplets on TC4 and 304SS plates. The results show that the CO2 + Ar gas atmosphere significantly affects interfacial mass transfer, thus influencing the wettability of the systems.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Jimei Liu, Fei Wang, Rong Guo, Yuqi Liu, Mengyu Zhang, Jaka Sunarso, Dong Liu
Summary: This study developed Co/MXene composites with anti-corrosion properties by varying the cobalt content. These composites exhibited remarkable electromagnetic absorption performance and high resistance to corrosion under various corrosive conditions. The study also revealed the mechanism of electron transfer from cobalt to MXene and the electromagnetic dissipation behavior originated from polarization loss alone.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Moujie Huang, Yongsong Ma, Jingbo Yang, Lingyun Xu, Hangqi Yang, Miao Wang, Xin Ma, Xin Xia, Junhao Yang, Deli Wang, Chuang Peng
Summary: Strong metal-support interactions (SMSIs) are important for enhancing catalytic activities and stability in thermal catalysis. This study demonstrates a method to create SMSIs in electrocatalysis using carbon nanotubes and Ru nanoparticles, resulting in excellent catalytic activity and stability.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Ravi Trivedi, Brinti Mondal, Nandini Garg, Brahmananda Chakraborty
Summary: This study explores the potential of biphenylene as a nanocarrier for the delivery of the anticancer drug cisplatin. It is found that biphenylene offers physical stability, rapid release rate, solubility, and bio-compatibilities compared to other nanocarriers. The adsorption of cisplatin on the surface of biphenylene involves charge transfer from cisplatin to biphenylene. The drug is shown to be released at body temperature in an acidic environment. Biphenylene also exhibits excellent cytotoxicity activity and cellular uptake of the drug. Overall, biphenylene shows promise as a potential nanocarrier for cisplatin delivery.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Hyun Jeong, Hyeong Chan Suh, Ga Hyun Cho, Rafael Salas-Montiel, Hayoung Ko, Ki Kang Kim, Mun Seok Jeong
Summary: In this study, a potential platform to enhance Raman scattering and increase the number of observable Raman modes in monolayer transition metal dichalcogenides (TMDs) was proposed. The platform consisted of large-scale arrays of gold micropillars (MPs), which were able to enhance the Raman intensity of TMDs and make difficult-to-detect Raman modes observable. The platform showed great industrial advantages and wide applicability due to its low cost, simple process, large controllable area, and short process time.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yasir Abbas, Shafqat Ali, Sajjad Ali, Waqar Azeem, Zareen Zuhra, Haoliang Wang, Mohamed Bououdina, Zhenzhong Sun
Summary: In this study, FeOx@SPNO-C core-shell nanospheres as a catalyst for degradation of sulfamethoxazole (SMX) were successfully synthesized. The synergistic interaction between FeOx and SPNO-C, high carbon charge density, and the presence of C = O groups and N/Fe-Nx sites were found to be key factors for the enhanced degradation of SMX.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Qiaoting Yang, Yuxiao Gong, Yan Qian, Zhou-Qing Xiao, Serge Cosnier, Xue-Ji Zhang, Robert S. Marks, Dan Shan
Summary: This study proposes a hierarchical confinement strategy to design Prussian blue nanoparticles (PB NPs) with satisfactory electrocatalytic ability and stability. The catalytic synthesis of PB NPs is achieved through a hydrothermal process, and the as-prepared PB@NH2MIL exhibits efficient electronic transmission and enhanced electrocatalytic properties.
APPLIED SURFACE SCIENCE
(2024)