期刊
APPLIED SURFACE SCIENCE
卷 288, 期 -, 页码 625-632出版社
ELSEVIER
DOI: 10.1016/j.apsusc.2013.10.085
关键词
Polymer silver nanocomposite; Tyrosine; Antifilarial activity; Apoptosis
类别
资金
- CSIR [01(2444)/10/EMR-II]
- DST [SR/S3/ME/0018/2010]
Poly(vinyl alcohol) (PVA) capped stable silver nanoparticles (AgNP) have been synthesized sonochemically with the help of catalytic amount of a biomolecule (tyrosine). An attempt has been made to reduce the harmfull chemical additives (like sodium borohydride, hydrazine, dimethyl formamide, etc.) used in conventional methods. Tyrosine shows excellent reducing activity in presence of PVA stabilizer. Ultrasound increased the reaction rate and yield, and improved the quality of the AgNP in terms of regular size distribution. The synthetic route follows the principles of green chemistry. Bioactivity has been tested in the light of antifilarial efficacy through induction of apoptosis. The biocompatible polymer (PVA) capped AgNPs are suitable for the treatment of filarial nematode. (C) 2013 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据