Article
Multidisciplinary Sciences
Mareeswari Paramasivan, T. S. Sampath Kumar, Hemalatha Kanniyappan, Vignesh Muthuvijayan, T. S. Chandra
Summary: Biomimicry has been adopted in bioceramics due to its functional advantages. In this study, hydroxyapatite synthesized via biomimetic approach was substituted with individual and multiple cations. The substituted hydroxyapatite showed decreased crystallinity, phase purity, and altered morphology. The co-substituted hydroxyapatite with 1% Sr, Zn, and Mg showed promising biocompatibility.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Multidisciplinary
Edoardo Cianflone, Fabien Brouillet, David Grossin, Jeremy Soulie, Claudie Josse, Sanjana Vig, Maria Helena Fernandes, Christophe Tenailleau, Benjamin Duployer, Carole Thouron, Christophe Drouet
Summary: Biomimetic apatites have high reactivity and can be modulated by ion substitutions for in vivo response. A novel approach was developed to combine bioactive ions in a spatially controlled manner for subsequent releases. The concept was validated by developing core-shell particles with antibacterial ions in the outer shell and pro-angiogenic or osteogenic ions in the inner core.
Review
Pharmacology & Pharmacy
Kannappan Arunachalam, Poonguzhali Pandurangan, Chunlei Shi, Ricardo Lagoa
Summary: Staphylococcus aureus is a versatile pathogen that causes various infections. It is important to understand its pathogenesis and develop new treatment strategies, especially against drug-resistant strains. Nanomaterials offer a potential solution to control S. aureus infections, including intracellular parasitism and multidrug resistance. This review focuses on the impact of S. aureus on human health, the role of virulence factors and biofilms, the applications of nanoparticles in controlling infections, and the prospects and limitations of nanomaterial-based therapies.
Article
Materials Science, Multidisciplinary
D. Mashtalyar, K. Nadaraia, N. G. Plekhova, I. M. Imshinetskiy, M. A. Piatkova, A. Pleshkova, S. E. Kislova, S. L. Sinebryukhov, S. Gnedenkov
Summary: Antibacterial coatings were formed on Mg alloy through plasma electrolytic oxidation and subsequent antibiotic impregnation. The coatings exhibited significant antibacterial activity against S. aureus and methicillin-resistant S. aureus in an in vitro model.
Article
Engineering, Biomedical
Ika Dewi Ana, Any Lestari, Prescillia Lagarrigue, Jeremy Soulie, Rahmi Anggraeni, Francoise Maube-Bosc, Carole Thouron, Benjamin Duployer, Christophe Tenailleau, Christophe Drouet
Summary: This study establishes a safe-by-design bone substitute approach by combining bone-like apatite to peroxide ions close to natural in vivo oxygenated species aimed at fighting pathogens. The doped apatites demonstrated significant antibacterial properties and high biocompatibility, making them promising candidates in dentistry and orthopedics.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Tierong Bian, Ni Pang, Hongyun Xing
Summary: A parallel-aligned beta-tricalcium phosphate/collagen composite nanofiber scaffold with a microstructure similar to natural bone matrix membrane was fabricated, and crosslinked with glutaraldehyde to enhance its stability. The scaffold not only promotes biomimetic apatite-like mineral deposition and bone integration during repair, but also exhibits compatibility with bone marrow mesenchymal stem cells and strong antibacterial activity against E.coli. This composite nanofiber scaffold provides a new bioactive bone scaffold material for bone defect repair with antibacterial properties.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Biochemistry & Molecular Biology
Zhao Deng, Rammohan R. Yadav Bheemanaboina, Yan Luo, Cheng-He Zhou
Summary: Aloe emodin-conjugated sulfonyl hydrazones, specifically AEBH-5a, show high selectivity and antibacterial activity against S. aureus, being able to eliminate biofilms and reduce antibiotic resistance. The mechanisms of action include disruption of bacterial membrane integrity, induction of oxidative stress, inhibition of lactate dehydrogenase activity, and metabolic inactivation. In silico studies also suggest favorable bioavailability and drug-likeness profiles for AEBH-5a.
BIOORGANIC CHEMISTRY
(2022)
Article
Polymer Science
Daniela Filip, Doina Macocinschi, Cristina Gabriela Tuchilus, Mirela Fernanda Zaltariov, Cristian Dragos Varganici
Summary: The study focuses on the structure and properties of new four-arm star poly(ether urethanes) based on erythromycin propionate core, utilizing various analytical methods such as IR spectroscopy and NMR. The synthesized star PUs exhibit higher melting temperatures and thermal stability, and their antibacterial properties were evaluated.
MACROMOLECULAR RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Ravikumar Akunuri, Tanveer M. Unnissa, Grace Kaul, Abdul Akhir, Deepanshi Saxena, Mohmadd Wajidali, Vaishnavi Veerareddy, Venkata Madhavi Yaddanapudi, Sidharth Chopra, Srinivas Nanduri
Summary: Antimicrobial resistance is a serious challenge to modern medicine, and Rhodanine and related 5-membered heterocycles show potential as candidate compounds for the development of new antimicrobial drugs.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Biotechnology & Applied Microbiology
Moj Khaleghi, Sadegh Khorrami
Summary: This study demonstrated that an extract has good antibacterial and anti-biofilm activity against multidrug-resistant MRSA. It inhibits biofilm formation, destroys pre-formed biofilm, and affects bacterial cells within the biofilm, while also down-regulating the expression of key genes involved in biofilm formation.
Article
Microbiology
Sanaa M. F. Gad El-Rab, Aly E. Abo-Amer, Ahlam M. Asiri
CURRENT MICROBIOLOGY
(2020)
Article
Nanoscience & Nanotechnology
Eman M. Halawani, Aziza M. Hassan, Sanaa M. F. Gad El-Rab
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2020)
Article
Nanoscience & Nanotechnology
Enas Tawfik Enan, Amal A. Ashour, Sakeenabi Basha, Nayef H. Felemban, Sanaa M. F. Gad El-Rab
Summary: This study synthesized silver nanoparticles and incorporated them with amoxicillin into glass ionomer cement, demonstrating a synergistic effect on oral microbes with excellent antimicrobial properties, significant inhibitory zone diameters, and the ability to disrupt bacterial biofilms. The addition of these antimicrobial agents had minimal effect on the compressive strength of GIC, making them a safe and effective choice for dental restorations.
Article
Biotechnology & Applied Microbiology
Sanaa M. F. Gad El-Rab, Eman M. Halawani, Seham S. S. Alzahrani
Summary: The study involved the synthesis of silver nanoparticles (AgNPs) from an aqueous extract of Juniperus excelsa and their use as an antimicrobial agent. AgNPs showed synergistic efficacy with Cefaclor, Cefoxitin, and Erythromycin antibiotics in inhibiting multidrug-resistant bacteria.
Article
Biotechnology & Applied Microbiology
Sanaa M. F. Gad El-Rab, Sakeenabi Basha, Amal A. Ashour, Enas Tawfik Enan, Amal Ahmed Alyamani, Nayef H. Felemban
Summary: The study explored the antibacterial efficacy of copper nanoparticles synthesized using Cupressus macrocarpa extract (CME) against periodontitis-causing bacteria. Results showed superior antimicrobial properties of CME-CuNPs compared to reported values in literature, and their synergistic effect with clindamycin in preventing bacterial growth.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Amal Adnan Ashour, Sakeenabi Basha, Nayef H. Felemban, Enas T. Enan, Amal Ahmed Alyamani, Sanaa M. F. Gad El-Rab
Summary: In this study, Zingiber officinale was used to synthesize Zingiber officinale capped silver nanoparticles (ZOE-AgNPs), and their antimicrobial efficacy and compressive strength were compared with conventional glass ionomer cement (GIC) combined with other substances. It was found that the combination of ZOE-AgNPs and chlorhexidine enhanced both antimicrobial efficacy and compressive strength when compared to using ZOE-AgNPs or other substances alone.
Article
Biochemistry & Molecular Biology
Sanaa M. F. Gad El-Rab, Amal A. Ashour, Sakeenabi Basha, Amal Ahmed Alyamani, Nayef H. Felemban, Enas Tawfik Enan
Summary: This study evaluated the antibacterial activity of a newly synthesized nanoantibiotic-Biodentine formulation against S. mutans. The Cefuroxime-ROE-AgNPs displayed the highest antibacterial efficacy with a MIC of 8.5 µg/mL, showing a three-fold decrease compared to ROE-AgNPs alone. The novel material Cefuroxime-ROE-AgNPs/BIOD exhibited maximum antimicrobial activity against S. mutans, with inhibitory zones of 19 mm and 26 mm, and antimicrobial rates of 85.78% and 91.17%.
Article
Microbiology
Amal W. Danial, Shereen M. Hamdy, Sulaiman A. Alrumman, Sanaa M. F. Gad El-Rab, Ahmed A. M. Shoreit, Abd El-Latif Hesham
Summary: A high-producing strain of Bacillus wiedmannii AS-02 OK576278 was identified for PHB production from agricultural wastes. The optimum conditions for PHB production were pH 7, temperature 35°C, and 72 hours of incubation. The strain was able to accumulate significant amounts of PHB from various agricultural waste sources.
Article
Infectious Diseases
Amal Adnan Ashour, Mohammed Fareed Felemban, Nayef H. Felemban, Enas T. Enan, Sakeenabi Basha, Mohamed M. Hassan, Sanaa M. F. Gad El-Rab
Summary: The use of Thymus vulgaris extract to synthesize copper nanoparticles (TVE-CuNPs) can enhance the antimicrobial properties of restorative biomaterials and reduce the recurrence of caries lesions. The combination of TVE-CuNPs, commercial silver nanoparticles (AgNPs), and metronidazole with glass ionomer cement (GIC) showed improved antibacterial efficacy and compressive strength. The modified GIC samples, especially those with a combination of TVE-CuNPs or AgNPs with metronidazole, demonstrated enhanced antimicrobial efficiency against Staphylococcus aureus and Streptococcus mutans.
Article
Microbiology
Shereen M. Hamdy, Amal W. Danial, Sanaa M. F. Gad El-Rab, Ahmed A. M. Shoreit, Abd El-Latif Hesham
Summary: In this study, a strain of PHB-producing bacterium was isolated from the Dirout channel in Assiut Governorate and identified as Bacillus cereus SH-02. The effects of carbon source, nitrogen source, and pH on PHB production were studied using a series of experiments and response surface methodology. The polymer was confirmed as PHB through FTIR, NMR, and mass spectrometry analysis. The results demonstrated that the production of PHB can be significantly improved by optimizing the cultivation conditions.
Article
Chemistry, Applied
Amal Adnan Ashour, Nayef H. Felemban, Enas T. Enan, Sakeenabi Basha, Sanaa M. F. Gad El-Rab
Summary: The combination of silver and zinc oxide nanoparticles with chitosan and erythromycin has been shown to have antibacterial and antibiofilm properties against oral bacterial diseases. These nanoparticles caused cell membrane damage and could be used in dental applications.
JOURNAL OF BIOBASED MATERIALS AND BIOENERGY
(2022)
Article
Chemistry, Applied
Sanaa M. F. Gad El-Rab, Eman M. Halawani, Aly E. Abo-Amer, Nadia H. Mohamed, Ahlam M. Asiri
Summary: Extended-spectrum beta-lactamase (ES beta L) producing E. coli is a significant medical challenge. Recent studies have shown that silver nanoparticles (AgNPs) have antimicrobial effects, which can be combined with ampicillin to enhance the antibacterial efficiency against ES beta L-producing E. coli.
JOURNAL OF BIOBASED MATERIALS AND BIOENERGY
(2022)
Article
Biotechnology & Applied Microbiology
Aly E. Abo-Amer, Sanaa M. F. Gad El-Rab, Eman M. Halawani, Ameen M. Niaz, Mohammed S. Bamaga
Summary: This research investigated the prevalence of MRSA in Taif, Saudi Arabia and examined the relationship between antimicrobial sensitivity patterns and resistance genes. The study also found that silver nanoparticles showed high antimicrobial activity and synergistic effect with penicillin against MRSA isolates.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Shereen M. Hamdy, Amal W. Danial, Eman M. Halawani, Ahmed A. M. Shoreit, Abd El-Latif Hesham, Sanaa M. F. Gad El-Rab
Summary: This study describes wound dressing materials made from biodegradable polyhydroxybutyrate (PHB) combined with AgNPs and gelatin (AgNPs/Gelatin/PHB). The results show that AgNPs/Gelatin/PHB exhibits excellent antimicrobial efficacy against bacteria and facilitates a better wound healing process.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Multidisciplinary
Eman M. S. Halawani, Seham S. S. Alzahrani, Sanaa M. F. Gad El-Rab
Summary: The prevalence of multidrug-resistant bacteria is increasing and poses a serious threat to human health. This study developed a novel drug delivery system using amoxicillin-conjugated gold nanoparticles to overcome MDR bacteria. The results demonstrated the superior antibacterial effectiveness of this system against MRSA and MDR E. coli strains, indicating its potential for improving therapeutic action.
Article
Chemistry, Physical
Qi-Wen Chen, Ze-Qing Guo, Jian-Ping Zhou
Summary: Multifunctional continuous solid solutions NFMTO-x were successfully synthesized via a one-step hydrothermal method by controlling the ratio of Mg and Fe. The NFMTO-x materials exhibited enhanced visible light response, effective adsorption and photocatalytic degradation of organic pollutants, CO2 methanation capability, and easy recyclability due to their magnetic properties. This research provides a significant multifunctional material for water purification.
APPLIED SURFACE SCIENCE
(2024)
Review
Chemistry, Physical
George E. Stan, Maziar Montazerian, Adam Shearer, Bryan W. Stuart, Francesco Baino, John C. Mauro, Jose M. F. Ferreira
Summary: Bioactive glasses have the ability to form strong bonds with tissues and release therapeutic ions. However, their biomechanical compatibility limits their use in load-bearing applications. The use of magnetron sputtering technology to fabricate BG coatings shows promise in improving their efficacy and potential for application.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Zhaoxuan Wang, Zhicheng Yan, Zhigang Qi, Yu Feng, Qi Chen, Ziqi Song, Meng Huang, Peng Jia, Ki Buem Kim, Weimin Wang
Summary: The corrosion behavior of Fe-60 and Fe-83 ribbons in 0.6 M NaCl was studied. Fe-60 exhibited a local corrosion mode and formed a stable passivation film with higher corrosion resistance, while Fe-83 showed a combination of local and global corrosion modes and had lower corrosion resistance. Controlling the precipitation of nanocrystalline phases and increasing the POx content in the passivation film significantly improved the corrosion resistance of Fe-based glassy alloys.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Hao-Kai Peng, Sheng-Yen Zheng, Wei-Ning Kao, Ting-Chieh Lai, Kai-Sheun Lee, Yung- Hsien Wu
Summary: This study investigates the effects of high energy/fluence proton radiation on the performance of HfZrOx-based FeFETs memory with different Zr content. The results show that the characteristics of FeFETs are influenced by proton radiation, and the extent of the influence depends on the Zr content. FeFETs with 50% Zr content exhibit minimal changes in memory window and demonstrate good endurance and retention performance.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Zongyi Yue, Guangyi Wang, Zengguang Huang, Sihua Zhong
Summary: In this study, AZO and ITO films were successfully tuned as excellent passivation layers for c-Si surfaces, achieving effective minority carrier lifetime and outstanding optical properties through the optimization of annealing temperature and interfacial silicon oxide.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Martin Hruska, Jan Kejzlar, Jaroslav Otta, Premysl Fitl, Michal Novotny, Jakub Cizek, Oksana Melikhova, Matej Micusik, Peter Machata, Martin Vrnata
Summary: This paper presents a detailed study on the hydrogen sensing capabilities of highly nanoporous black gold films. The films exhibit fast response and recovery times at low temperatures. Different levels of nanoporosity were prepared and tested to investigate the sensing properties, and it was found that nanoporous black gold is suitable for hydrogen sensing. The sensitivity of the film depends on its nanoporosity.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yupu Wang, Gaofeng Teng, Chun To Yiu, Junyi Zhu
Summary: In the study of BM-SCO and HSCO thin films, it was found that H vacancies tend to prefer sites near the external surface or oxygen vacancy channels (OVCs), while H interstitials prefer sites of oxygen on a layer that contains six-fold coordinated Co. These findings not only enrich the understanding of complex surface phenomena of defect formation but also provide an explanation for the reversibility during phase transformation.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Jiafeng Lu, Linping Teng, Qinxiao Zhai, Chunhua Wang, Matthieu Lancry, Ye Dai, Xianglong Zeng
Summary: In this study, we achieved full control of fiber nanograting orientation by manipulating laser polarization, and tailored space variant fiber nanogratings, which expanded the diversity in fiber nanograting engineering.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yibo Liu, Yujie Tao, Yue Liu, Qi Sun, Qinrong Lin, Kexin Kang, Qinghua Zhang, Qingjie Sun
Summary: This study investigates the wettability of the Ti-Cu-Fe multi-metal system, specifically the wetting behaviors of CuSi3 droplets on TC4 and 304SS plates. The results show that the CO2 + Ar gas atmosphere significantly affects interfacial mass transfer, thus influencing the wettability of the systems.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Jimei Liu, Fei Wang, Rong Guo, Yuqi Liu, Mengyu Zhang, Jaka Sunarso, Dong Liu
Summary: This study developed Co/MXene composites with anti-corrosion properties by varying the cobalt content. These composites exhibited remarkable electromagnetic absorption performance and high resistance to corrosion under various corrosive conditions. The study also revealed the mechanism of electron transfer from cobalt to MXene and the electromagnetic dissipation behavior originated from polarization loss alone.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Moujie Huang, Yongsong Ma, Jingbo Yang, Lingyun Xu, Hangqi Yang, Miao Wang, Xin Ma, Xin Xia, Junhao Yang, Deli Wang, Chuang Peng
Summary: Strong metal-support interactions (SMSIs) are important for enhancing catalytic activities and stability in thermal catalysis. This study demonstrates a method to create SMSIs in electrocatalysis using carbon nanotubes and Ru nanoparticles, resulting in excellent catalytic activity and stability.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Ravi Trivedi, Brinti Mondal, Nandini Garg, Brahmananda Chakraborty
Summary: This study explores the potential of biphenylene as a nanocarrier for the delivery of the anticancer drug cisplatin. It is found that biphenylene offers physical stability, rapid release rate, solubility, and bio-compatibilities compared to other nanocarriers. The adsorption of cisplatin on the surface of biphenylene involves charge transfer from cisplatin to biphenylene. The drug is shown to be released at body temperature in an acidic environment. Biphenylene also exhibits excellent cytotoxicity activity and cellular uptake of the drug. Overall, biphenylene shows promise as a potential nanocarrier for cisplatin delivery.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Hyun Jeong, Hyeong Chan Suh, Ga Hyun Cho, Rafael Salas-Montiel, Hayoung Ko, Ki Kang Kim, Mun Seok Jeong
Summary: In this study, a potential platform to enhance Raman scattering and increase the number of observable Raman modes in monolayer transition metal dichalcogenides (TMDs) was proposed. The platform consisted of large-scale arrays of gold micropillars (MPs), which were able to enhance the Raman intensity of TMDs and make difficult-to-detect Raman modes observable. The platform showed great industrial advantages and wide applicability due to its low cost, simple process, large controllable area, and short process time.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yasir Abbas, Shafqat Ali, Sajjad Ali, Waqar Azeem, Zareen Zuhra, Haoliang Wang, Mohamed Bououdina, Zhenzhong Sun
Summary: In this study, FeOx@SPNO-C core-shell nanospheres as a catalyst for degradation of sulfamethoxazole (SMX) were successfully synthesized. The synergistic interaction between FeOx and SPNO-C, high carbon charge density, and the presence of C = O groups and N/Fe-Nx sites were found to be key factors for the enhanced degradation of SMX.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Qiaoting Yang, Yuxiao Gong, Yan Qian, Zhou-Qing Xiao, Serge Cosnier, Xue-Ji Zhang, Robert S. Marks, Dan Shan
Summary: This study proposes a hierarchical confinement strategy to design Prussian blue nanoparticles (PB NPs) with satisfactory electrocatalytic ability and stability. The catalytic synthesis of PB NPs is achieved through a hydrothermal process, and the as-prepared PB@NH2MIL exhibits efficient electronic transmission and enhanced electrocatalytic properties.
APPLIED SURFACE SCIENCE
(2024)
