Article
Chemistry, Analytical
Skaidre Jankovskaja, Maxim Morin, Anna Gustafsson, Chris D. Anderson, Boglarka Lehoczki, Johan Engblom, Sebastian Bjorklund, Meinda Rezeli, Gyorgy Marko-Varga, Tautgirdas Ruzgas
Summary: This study assessed various sampling approaches for tryptophan and kynurenine and found that the phenylalanine/tryptophan ratio may be a possible alternative biomarker for non-invasive skin cancer detection.
ANALYTICAL CHEMISTRY
(2022)
Article
Agriculture, Dairy & Animal Science
Lingwei Sun, Mengqian He, Caifeng Wu, Shushan Zhang, Jianjun Dai, Defu Zhang
Summary: Soy lecithin (SL) and its nanoparticles (nano-SL) can effectively prevent spermatozoa cryodamage during cryopreservation, with a concentration of 1.0% nano-SL showing the most positive impact on post-thawing semen quality and fertility in roosters. The addition of nano-SL reduced oxidative stress levels, improved sperm motility and mitochondrial activity, and enhanced fertility and hatchability in rooster semen after artificial insemination.
Article
Biochemistry & Molecular Biology
Mariia Nesterkina, Serhii Smola, Nataliya Rusakova, Iryna Kravchenko
Summary: Hydrazones based on mono- and bicyclic terpenoids have been investigated as potential biomembrane penetration enhancers. The mechanism of action of these hydrazones involves a reduction in lipid microviscosity and disruption of the hydrogen-bonded network of the lipid matrix.
Article
Physics, Multidisciplinary
Benjamin Foster, Nicolas Verschueren, Edgar Knobloch, Leonardo Gordillo
Summary: An exactly solvable family of models describing the wrinkling of substrate-supported inextensible elastic rings under compression is identified. The resulting wrinkle profiles are shown to be related to the buckled states of an unsupported ring and are therefore universal. Closed analytical expressions for the resulting universal shapes are provided, including the one-to-one relations between the pressure and tension at which these emerge. The analytical predictions agree with numerical continuation results to within numerical accuracy, for a large range of parameter values, up to the point of self-contact.
PHYSICAL REVIEW LETTERS
(2022)
Review
Materials Science, Biomaterials
Maedeh Rahimnejad, Fariba Rasouli, Sepideh Jahangiri, Sepideh Ahmadi, Navid Rabiee, Marzieh Ramezani Farani, Omid Akhavan, Mohsen Asadnia, Yousef Fatahi, Sanghoon Hong, Jungho Lee, Junmin Lee, Sei Kwang Hahn
Summary: This article reviews the preparation and characterization of biomimetic membranes and discusses their applications in organ-on-a-chip systems. Biomimetic membranes are considered as crucial components for developing controllable biomimetic bioanalysis systems.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2022)
Article
Polymer Science
Miroslava Spaglova, Maria Cuchorova, Martina Cierna, Silvester Ponist, Katarina Bauerova
Summary: The study evaluated the influence of different microemulsions on the solubilization and release of minoxidil, finding that the lecithin-containing microemulsion slowed down drug release compared to other samples and resulted in a higher residual drug amount in the skin after ex vivo diffusion.
Article
Multidisciplinary Sciences
Xin Wu, Patrick Wang, William Lewis, Yun-Bao Jiang, Philip A. Gale
Summary: This study investigates the quantification of anion binding within lipid bilayers using a fluorescent macrocycle with strong sulfate affinity. The authors discover that the determinants of anion binding in lipid bilayers differ from those in solution. These findings provide insights into the principles of anion binding within lipid bilayers and have implications for the design of functional molecular systems at biomembrane interfaces.
NATURE COMMUNICATIONS
(2022)
Review
Medicine, Research & Experimental
Ziqing Wu, Hao Zhang, Jing Yan, Yan Wei, Jiacan Su
Summary: Biological membrane engineering methods can enhance the functionality of biomembrane-derived nanoparticles for improved drug delivery and treatment. These methods can be applied to various biomembranes and are expected to play a significant role in the treatment and diagnosis of cancer, inflammation, immunological diseases, bone diseases, and Alzheimer's disease.
Article
Multidisciplinary Sciences
Jiawei Sun, Sjoerd J. Rijpkema, Jiabin Luan, Shaohua Zhang, Daniela A. Wilson
Summary: The formation of biomembrane curvature is crucial for changing cell structure and function, and can be mimicked using polymer systems. The observation of the insertion process is beneficial for further understanding of curvature formation processes.
NATURE COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Trine B. Haugen, Oliwia Witczak, Steven A. Hicks, Lars Bjorndahl, Jorunn M. Andersen, Michael A. Riegler
Summary: In this study, the performance of the DCNN ResNet-50 in predicting the proportion of sperm in different motility categories was evaluated. The DCNN models were able to accurately predict the sperm motility with significantly lower error than the baseline. The best correlation was found for progressive and immotile categories. However, there was considerable variation between the mean motility values obtained by the reference laboratories, which affected the training of the DCNN models.
SCIENTIFIC REPORTS
(2023)
Article
Toxicology
Huanqiang Wang, Siyun Zhou, Yi Liu, Yihan Yu, Sha Xu, Lan Peng, Chunhui Ni
Summary: This study aimed to characterize the serum metabolic profile of pneumoconiosis and artificial stone silicosis patients. Differential metabolites were identified that could predict the stages of pneuomoconiosis and serve as potential biomarkers for artificial stone silicosis. Tryptophan metabolism was found to be closely related to pneumoconiosis and may play a role in disease progression.
TOXICOLOGY LETTERS
(2022)
Article
Plant Sciences
Agata Kledecka, Przemyslaw Siejak, Anubhav Pratap-Singh, Przemyslaw Lukasz Kowalczewski, Farahnaz Fathordoobady, Maciej Jarzebski, Wojciech Smulek
Summary: This study investigated the antibacterial properties of Frangula alnus Mill (FAM) bark extract and how its bioactive properties are influenced by different solvents. The results showed that the chemical diversity of the extracts increased with the increase in solvent polarity. Ethanolic extracts had the strongest effect on the selected bacteria strains. Furthermore, the study found that FAM extracts had no direct effect on probiotic microorganisms and may reduce the total permeability of bacterial membranes.
Review
Biotechnology & Applied Microbiology
Jie Li, Huamin Zeng, Luwei Li, Ming Song, Mingqing Dong
Summary: Gene delivery for cancer treatment has made promising progress due to its high efficacy, low toxicity, and exclusive selectivity. However, there are still challenges in terms of delivery efficiency, specific biological distribution, targeted uptake, and biosafety of naked nucleic acid agents, which limit further clinical application. To overcome these obstacles, functional nanovectors, such as membrane-wrapped biomimetic nanoparticles (MBNPs), have been developed to improve the delivery efficiency of nucleic acid agents. This review discusses the mechanism of gene therapy, the current obstacles in gene delivery, and the latest developments in MBNPs for gene delivery, as well as strategies to overcome these obstacles.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Laszlo Imre, Erfaneh Firouzi Niaki, Rosevalentine Bosire, Peter Nanasi, Peter Nagy, Zsolt Bacso, Nubar Hamidova, Yves Pommier, Albert Jordan, Gabor Szabo
Summary: This study explores the roles and interactions of polyamines (PAs) in the nucleus, specifically their effect on nucleosome stability. The results demonstrate that PAs, such as spermine, spermidine, and putrescine, have a strong destabilizing effect on nucleosomes in the millimolar concentration range. This effect is dependent on pH and salt concentration, and remains significant even at neutral pH. It was also found that PA treatment does not affect the integrity of genomic DNA. Furthermore, the study shows that PAs bind to DNA, as evidenced by the displacement of ethidium bromide.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Yuchen Zhang, Keisuke Hamada, Masayuki Satake, Toru Sengoku, Yuki Goto, Hiroaki Suga
Summary: Prenyltransferases in cyanobactin biosynthesis have been engineered to modify their prenylation modes, leading to the discovery of a novel farnesylation mode. The understanding of essential residues for farnesyl-binding pocket construction has allowed for the rational design of additional peptide alkylation biocatalysts.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Physical
Qi-Wen Chen, Ze-Qing Guo, Jian-Ping Zhou
Summary: Multifunctional continuous solid solutions NFMTO-x were successfully synthesized via a one-step hydrothermal method by controlling the ratio of Mg and Fe. The NFMTO-x materials exhibited enhanced visible light response, effective adsorption and photocatalytic degradation of organic pollutants, CO2 methanation capability, and easy recyclability due to their magnetic properties. This research provides a significant multifunctional material for water purification.
APPLIED SURFACE SCIENCE
(2024)
Review
Chemistry, Physical
George E. Stan, Maziar Montazerian, Adam Shearer, Bryan W. Stuart, Francesco Baino, John C. Mauro, Jose M. F. Ferreira
Summary: Bioactive glasses have the ability to form strong bonds with tissues and release therapeutic ions. However, their biomechanical compatibility limits their use in load-bearing applications. The use of magnetron sputtering technology to fabricate BG coatings shows promise in improving their efficacy and potential for application.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Zhaoxuan Wang, Zhicheng Yan, Zhigang Qi, Yu Feng, Qi Chen, Ziqi Song, Meng Huang, Peng Jia, Ki Buem Kim, Weimin Wang
Summary: The corrosion behavior of Fe-60 and Fe-83 ribbons in 0.6 M NaCl was studied. Fe-60 exhibited a local corrosion mode and formed a stable passivation film with higher corrosion resistance, while Fe-83 showed a combination of local and global corrosion modes and had lower corrosion resistance. Controlling the precipitation of nanocrystalline phases and increasing the POx content in the passivation film significantly improved the corrosion resistance of Fe-based glassy alloys.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Hao-Kai Peng, Sheng-Yen Zheng, Wei-Ning Kao, Ting-Chieh Lai, Kai-Sheun Lee, Yung- Hsien Wu
Summary: This study investigates the effects of high energy/fluence proton radiation on the performance of HfZrOx-based FeFETs memory with different Zr content. The results show that the characteristics of FeFETs are influenced by proton radiation, and the extent of the influence depends on the Zr content. FeFETs with 50% Zr content exhibit minimal changes in memory window and demonstrate good endurance and retention performance.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Zongyi Yue, Guangyi Wang, Zengguang Huang, Sihua Zhong
Summary: In this study, AZO and ITO films were successfully tuned as excellent passivation layers for c-Si surfaces, achieving effective minority carrier lifetime and outstanding optical properties through the optimization of annealing temperature and interfacial silicon oxide.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Martin Hruska, Jan Kejzlar, Jaroslav Otta, Premysl Fitl, Michal Novotny, Jakub Cizek, Oksana Melikhova, Matej Micusik, Peter Machata, Martin Vrnata
Summary: This paper presents a detailed study on the hydrogen sensing capabilities of highly nanoporous black gold films. The films exhibit fast response and recovery times at low temperatures. Different levels of nanoporosity were prepared and tested to investigate the sensing properties, and it was found that nanoporous black gold is suitable for hydrogen sensing. The sensitivity of the film depends on its nanoporosity.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yupu Wang, Gaofeng Teng, Chun To Yiu, Junyi Zhu
Summary: In the study of BM-SCO and HSCO thin films, it was found that H vacancies tend to prefer sites near the external surface or oxygen vacancy channels (OVCs), while H interstitials prefer sites of oxygen on a layer that contains six-fold coordinated Co. These findings not only enrich the understanding of complex surface phenomena of defect formation but also provide an explanation for the reversibility during phase transformation.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Jiafeng Lu, Linping Teng, Qinxiao Zhai, Chunhua Wang, Matthieu Lancry, Ye Dai, Xianglong Zeng
Summary: In this study, we achieved full control of fiber nanograting orientation by manipulating laser polarization, and tailored space variant fiber nanogratings, which expanded the diversity in fiber nanograting engineering.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yibo Liu, Yujie Tao, Yue Liu, Qi Sun, Qinrong Lin, Kexin Kang, Qinghua Zhang, Qingjie Sun
Summary: This study investigates the wettability of the Ti-Cu-Fe multi-metal system, specifically the wetting behaviors of CuSi3 droplets on TC4 and 304SS plates. The results show that the CO2 + Ar gas atmosphere significantly affects interfacial mass transfer, thus influencing the wettability of the systems.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Jimei Liu, Fei Wang, Rong Guo, Yuqi Liu, Mengyu Zhang, Jaka Sunarso, Dong Liu
Summary: This study developed Co/MXene composites with anti-corrosion properties by varying the cobalt content. These composites exhibited remarkable electromagnetic absorption performance and high resistance to corrosion under various corrosive conditions. The study also revealed the mechanism of electron transfer from cobalt to MXene and the electromagnetic dissipation behavior originated from polarization loss alone.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Moujie Huang, Yongsong Ma, Jingbo Yang, Lingyun Xu, Hangqi Yang, Miao Wang, Xin Ma, Xin Xia, Junhao Yang, Deli Wang, Chuang Peng
Summary: Strong metal-support interactions (SMSIs) are important for enhancing catalytic activities and stability in thermal catalysis. This study demonstrates a method to create SMSIs in electrocatalysis using carbon nanotubes and Ru nanoparticles, resulting in excellent catalytic activity and stability.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Ravi Trivedi, Brinti Mondal, Nandini Garg, Brahmananda Chakraborty
Summary: This study explores the potential of biphenylene as a nanocarrier for the delivery of the anticancer drug cisplatin. It is found that biphenylene offers physical stability, rapid release rate, solubility, and bio-compatibilities compared to other nanocarriers. The adsorption of cisplatin on the surface of biphenylene involves charge transfer from cisplatin to biphenylene. The drug is shown to be released at body temperature in an acidic environment. Biphenylene also exhibits excellent cytotoxicity activity and cellular uptake of the drug. Overall, biphenylene shows promise as a potential nanocarrier for cisplatin delivery.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Hyun Jeong, Hyeong Chan Suh, Ga Hyun Cho, Rafael Salas-Montiel, Hayoung Ko, Ki Kang Kim, Mun Seok Jeong
Summary: In this study, a potential platform to enhance Raman scattering and increase the number of observable Raman modes in monolayer transition metal dichalcogenides (TMDs) was proposed. The platform consisted of large-scale arrays of gold micropillars (MPs), which were able to enhance the Raman intensity of TMDs and make difficult-to-detect Raman modes observable. The platform showed great industrial advantages and wide applicability due to its low cost, simple process, large controllable area, and short process time.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yasir Abbas, Shafqat Ali, Sajjad Ali, Waqar Azeem, Zareen Zuhra, Haoliang Wang, Mohamed Bououdina, Zhenzhong Sun
Summary: In this study, FeOx@SPNO-C core-shell nanospheres as a catalyst for degradation of sulfamethoxazole (SMX) were successfully synthesized. The synergistic interaction between FeOx and SPNO-C, high carbon charge density, and the presence of C = O groups and N/Fe-Nx sites were found to be key factors for the enhanced degradation of SMX.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Qiaoting Yang, Yuxiao Gong, Yan Qian, Zhou-Qing Xiao, Serge Cosnier, Xue-Ji Zhang, Robert S. Marks, Dan Shan
Summary: This study proposes a hierarchical confinement strategy to design Prussian blue nanoparticles (PB NPs) with satisfactory electrocatalytic ability and stability. The catalytic synthesis of PB NPs is achieved through a hydrothermal process, and the as-prepared PB@NH2MIL exhibits efficient electronic transmission and enhanced electrocatalytic properties.
APPLIED SURFACE SCIENCE
(2024)