Article
Biochemistry & Molecular Biology
Andre Luis Araujo Minari, Felipe Avila, Lila Missae Oyama, Ronaldo Vagner Thomatieli dos Santos
Summary: This study aimed to evaluate the relationship between exercise inflammation and the peripheral neuroendocrine system, finding that increased nAChR receptors may contribute to skeletal muscle adaption after exercise.
Article
Sport Sciences
Marcel Lemire, Thomas J. Hureau, Fabrice Favret, Bernard Geny, Blah Y. L. Kouassi, Mourad Boukhari, Evelyne Lonsdorfer, Romain Remetter, Stephane P. Dufour
Summary: This study investigated the cardiorespiratory responses of highly trained runners in outdoor downhill and uphill time-trials and explored the determinants of downhill and uphill performance. Results showed that both downhill and uphill performances are well explained by three independent predictors, with one specific predictor for each type of performance.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2021)
Article
Hospitality, Leisure, Sport & Tourism
Arash Khassetarash, Gianluca Vernillo, Renata L. Kruger, W. Brent Edwards, Guillaume Y. Millet
Summary: This study investigated the effects of the repeated bout effect (RBE) on neuromuscular performance, running biomechanics, and metabolic cost of running using downhill running as a model. The results demonstrated that RBE can attenuate muscle soreness and reduce serum creatine kinase levels. It also showed a decrease in maximum voluntary contraction force loss and voluntary activation. However, changes in running biomechanics did not significantly affect the energy cost of running.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2022)
Article
Physiology
Wei Luo, Yue Zhou, Qiang Tang, Lei Ai, Yuan Zhang
Summary: The study demonstrates that downhill running along with a low-fat diet can alleviate high-fat diet-induced insulin resistance, reduce inflammation levels, inhibit inflammation in adipose tissue, promote the activation of M2 macrophages.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Biophysics
Arash Khassetarash, Ifaz Haider, Michael Baggaley, W. Brent Edwards
Summary: This study examined the influence of neuromuscular fatigue on bone strains in the lower extremity. The results showed that neuromuscular fatigue affected ankle joint contact forces, but did not significantly affect tibial strains.
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME
(2023)
Article
Multidisciplinary Sciences
Aysel Yildirim, Muaz Belviranli, Nilsel Okudan
Summary: Low-intensity eccentric exercise training performed before high-intensity eccentric exercise can reduce muscle damage by decreasing oxidative stress and increasing antioxidant defense.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2022)
Article
Nutrition & Dietetics
Tarfa Albrahim, Raghad Alangry, Raghad Alotaibi, Leen Almandil, Sara Alburikan
Summary: A study investigated the effects of physical exercise and intermittent fasting on oxidative stress, neuroinflammation, and neurotransmitters in the cortex of rats. The results showed that exercise and fasting protected against ovariectomy-induced neuronal impairment, reduced oxidative stress and neuroinflammation, and increased the level of BDNF in the brain cortex.
Editorial Material
Hematology
Laurent A. Messonnier
Summary: Although sickle cell disease (SCD) is related to a single point mutation, there is extreme variability in the clinical presentation among patients. Genetic variants may contribute to this variability. In this study, Dosunmu-Ogunbi et al. highlighted the importance of a genetic variant affecting mitochondrial function in the cardiovascular pathophysiology of SCD. Their findings provide important insights and perspectives for patient management.
Article
Medicine, Research & Experimental
Hossein Amiri, Fatemeh Shabkhiz, Parisa Pournemati, Amir Hossein Saffar Kohneh Quchan, Reza Zeighami Fard
Summary: This study investigated the effects of swimming exercise on oxidative stress and liver cell damage caused by electromagnetic radiation in rats. The results showed that swimming exercise attenuated the liver damage caused by electromagnetic radiation. In the electromagnetic radiation group, the activity of superoxide dismutase and catalase decreased significantly, and the concentration of malondialdehyde and liver enzymes increased significantly; while in the swimming exercise and electromagnetic radiation + swimming exercise groups, the activity of superoxide dismutase and catalase increased significantly, and the concentration of malondialdehyde and liver enzymes decreased significantly.
Article
Medicine, Research & Experimental
Yan Gao, Zhaoyun Yang, Kang He, Zeyu Wang, Tingyu Zhang, Jiang Yi, Lijing Zhao
Summary: This study found that exercise has anti-inflammatory and antioxidant effects on pulmonary fibrosis induced by paraquat, reducing the infiltration of inflammatory cells and fibrotic lesions. Furthermore, exercise also increased the expression of antioxidative distress proteins, improved the degree of epithelial-mesenchymal transition in alveolar epithelial cells, and ultimately alleviated paraquat-induced pulmonary fibrosis.
Article
Sport Sciences
Jordan Philpott, Mark Kern, Shirin Hooshmand, Imogene Carson, Vernon Rayo, Elise North, Lauren Okamoto, Timothy O'Neil, Mee Young Hong, Changqi Liu, Gillian Dreczkowski, Nidia Rodriguez-Sanchez, Oliver C. C. Witard, Stuart D. D. Galloway
Summary: The study aimed to examine the effects of pistachio nut consumption on muscle soreness and function after exercise-induced muscle damage. Male team-sport players consumed either control (water), a standard dose of daily pistachios, or a higher dose of daily pistachios. The results showed that the high dose pistachio nut intake reduced quadriceps soreness during exercise recovery, but had no effect on muscle function. Therefore, high dose pistachio nut ingestion may alleviate muscle soreness after muscle damage.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Marta Nowacka-Chmielewska, Konstancja Grabowska, Mateusz Grabowski, Patrick Meybohm, Malgorzata Burek, Andrzej Malecki
Summary: Regular physical activity has positive effects on the central nervous system, increasing stress resilience, improving mood and cognitive abilities, reducing inflammation, and showing potential in preventing and treating neurologic diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Engineering, Biomedical
Takuto Toriumi, Ahram Kim, Shoichi Komine, Ikuru Miura, Suminori Nagayama, Hajime Ohmori, Yukio Nagasaki
Summary: The study demonstrates that the nanoparticle antioxidant RNP can significantly improve exercise performance in rats, increasing their all-out running time, while the use of low molecular weight antioxidants reduces running time and leads to a decrease in red blood cell count and an increase in oxidative stress.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Endocrinology & Metabolism
Xianghe Chen, Peng Sun, Aiguo Chen, Haixia Peng, Xianliang Zhang, Kang Yang, Huilin Yu, Renqing Zhao
Summary: Downhill running can promote bone formation ability and bone mineralization ability by activating the TGF-0/Smad pathway. It increases bone density and alkaline phosphatase activity, improves bone mass and bone tissue morphology, and enhances osteoblastic differentiation and mineralized nodule formation.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Andrology
Mozaffari Nazanin, Javad Tolouei-Azar, Mazdak Razi
Summary: This study investigated the effects of running exercise training protocols with different intensities on testicular redox and antioxidant capacities, as well as the crosstalk between oxidative stress and mitochondria-related apoptosis. The results showed that high-intensity running exercise significantly affected testicular development, sperm count, and antioxidant capacity, and may trigger mitochondria-related apoptosis.
Article
Environmental Sciences
Luciano Acordi da Silva, Lorhan da Silva Menguer, Ramiro Doyenart, Daniel Boeira, Yuri Pinheiro Milhomens, Beatriz Dieke, Ana Maria Volpato, Anand Thirupathi, Paulo Cesar Silveira
Summary: The study found that linear intensity aquatic exercise can improve mental health, functional autonomy, and oxidative dysfunction in elderly individuals with type 2 diabetes.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2022)
Article
Engineering, Biomedical
Germano Duarte Porto, Daniela Pacheco dos Santos Haupenthal, Priscila Soares Souza, Gustavo de Bem Silveira, Renata Tiscoski Nesi, Paulo Emilio Feuser, Jonathann Correa Possato, Vanessa Moraes de Andrade, Ricardo Aurino Pinho, Paulo Cesar Lock Silveira
Summary: This study evaluated the therapeutic effects of gold nanoparticles on chronic obstructive pulmonary disease, showing significant effects in reducing oxidative stress and inflammation with different doses of GNPs. The highest dose showed the best anti-inflammatory effects, while the dose of 7.5 mg/L of GNPs demonstrated better efficacy in reducing DNA damage.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2022)
Article
Biochemical Research Methods
Cecilia do Amparo Manoel, Samara de Sousa Mariano, Ericsson da Silva Ramos, Fernanda Rossi Paolillo, Andrea Aparecida de Aro, Carolini Mendes, Ligia Milanez Venturini, Paulo Cesar Lock Silveira, Vanderlei Salvador Bagnato, Thiago Antonio Moretti de Andrade
Summary: PBM and PDT have been found to be effective in treating skin lesions caused by electrocautery, reducing scarring and promoting tissue repair. These therapies work by controlling inflammation and oxidative stress, and promoting angiogenesis and collagen formation.
JOURNAL OF BIOPHOTONICS
(2022)
Editorial Material
Physiology
Anand Thirupathi, Yaodong Gu, Huw David Wiltshire, Ricardo A. Pinho
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Dora Aczel, Bernadett Gyorgy, Peter Bakonyi, RehAn BukhAri, Ricardo Pinho, Istvan Boldogh, Gu Yaodong, Zsolt Radak
Summary: Alzheimer's disease is a complex disorder that affects not only the brain but also other organs in the body. Regular physical activity has been found to have a positive impact on the disease, although effective medications have not yet been discovered.
Review
Immunology
Ricardo A. Pinho, Daniela P. S. Haupenthal, Paulo Emilio Fauser, Anand Thirupathi, Paulo C. L. Silveira
Summary: Gold nanoparticles (AuNPs) have anti-inflammatory and antioxidant properties, and can be used to control muscle inflammatory response and promote muscle regeneration. This review summarizes the effects of AuNPs on muscle inflammation and redox mechanisms by synthesizing the results of multiple studies.
JOURNAL OF INFLAMMATION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Amanda K. Costa, Luis F. B. Marqueze, Bruna B. Gattiboni, Giulia S. Pedroso, Franciane F. Vasconcellos, Eduardo B. B. Cunha, Hanna C. Justa, Antonielle B. Baldissera, Seigo Nagashima, Lucia de Noronha, Zsolt Radak, Luiz C. Fernandes, Ricardo A. Pinho
Summary: This study evaluated the effects of a physical exercise program on animals with experimental glioblastoma. The results showed that the trained animals exhibited changes in behavior and lower expression of certain proteins related to tumorigenesis. However, no significant alterations were observed in oxidative stress and inflammatory mediators after physical exercise. These findings provide consistent evidence for the relationship between exercise and improvement in tumorigenic parameters against neurotoxicity.
NEUROCHEMICAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Lucas Baena Carstens, Raissa Campos D'amico, Karen Fernandes de Moura, Eduardo Morais de Castro, Flavia Centenaro, Giovanna Silva Barbosa, Guilherme Vieira Cavalcante da Silva, Isadora Brenny, Julio Cesar Honorio D'Agostini, Elisa Carolina Hlatchuk, Sabrina Pissette de Lima, Ana Paula Camargo Martins, Marina De Castro Deus, Carolline Konzen Klein, Ana Paula Kubaski Benevides, Seigo Nagashima, Cleber Machado-Souza, Ricardo A. Pinho, Cristina Pellegrino Baena, Lucia de Noronha
Summary: The activation of the inflammasome complex is significantly increased in COVID-19 patients, indicating its involvement in the pathogenesis of the disease. Additionally, levels of cell pyroptosis and inflammasome-derived cytokines are greatly elevated.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Ramiro Doyenart, Daniel Boeira, Yuri Pinheiro Milhomens, Vitoria Oliveira Silva da Silva, Gislaine Zilli Reus, Paulo Cesar Lock Silveira, Luciano Acordi da Silva
Summary: The study examined the effects of aquatic exercise on functional autonomy, mental health, and oxidative dysfunction in elderly DM2 patients. A total of 130 elderly individuals were included and divided into non-diabetic and diabetic groups. Both groups participated in 24 sessions of Hydro-HIIT, and changes in various parameters were measured. The intervention resulted in improvements in functional autonomy, mental health, oxidative stress, and inflammatory response in elderly DM2 patients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Isio Carvalho de Souza, Aline Luri Takejima, Rossana Baggio Simeoni, Luize Kremer Gamba, Victoria Stadler Tasca Ribeiro, Katia Martins Foltz, Lucia de Noronha, Meila Bastos de Almeida, Jose Rocha Faria Neto, Katherine Athayde Teixeira de Carvalho, Paulo Cesar Lock da Silveira, Ricardo Aurino Pinho, Julio Cesar Francisco, Luiz Cesar Guarita-Souza
Summary: This study aimed to evaluate the effect of BMSCs and AM therapeutic strategies on tissue repair and found that AM + BMSCs could promote skin wound healing by promoting the production of new collagen through extracellular signaling.
Article
Engineering, Biomedical
Iago Carvalho Vendramini, Calue Papcke, Pedro Soares da Veiga Neto, Christiano Francisco dos Santos, Ricardo Aurino de Pinho, Eduardo Mendonca Scheeren
Summary: The study aimed to investigate the influence of pre-sarcopenia/sarcopenia on the ability of older adults to recover postural stability during balance perturbation. The results showed that older adults with pre-sarcopenia/sarcopenia required greater ankle plantarflexor activation to remain standing in response to perturbation compared to those without sarcopenia.
JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING
(2023)
Article
Immunology
Bruna Spolador de Alencar Silva, Telmo Pereira, Luciele Guerra Minuzzi, Camila Souza Padilha, Caique Figueiredo, Tiago Olean-Oliveira, Ivete Vera Medeiros dos Santos, Ana Elisa von Ah Morano, Osmar Marchioto, Jose Procopio Jabur Ribeiro, Vanessa Ribeiro Dos Santos, Marilia Seelaender, Alexandre Abilio Teixeira, Ronaldo Vagner T. Dos Santos, Valdir de Aquino Lemos, Ana Paula Coelho Figueira Freire, Gilson Pires Dorneles, Bruna Marmett, Andre Olean-Oliveira, Marcos F. S. Teixeira, Patricia M. Seraphim, Armando Caseiro, Ricardo Aurino Pinho, Hashim Islam, Jonathan Peter Little, Karsten Krueger, Jose Cesar Rosa-Neto, Manuel-Joao Coelho-E-Silva, Fabio Santos Lira
Summary: This study aimed to evaluate the association between physical activity and immunometabolic responses in young adults after mild-to-moderate COVID-19 infection. The results showed that COVID-19 patients had lower physical activity levels and exhibited impacts on lung function, immune cell phenotype, and cytokine production.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Luis F. B. Marqueze, Amanda K. Costa, Giulia S. Pedroso, Franciane F. Vasconcellos, Bruna I. Pilger, Schellen Kindermann, Vanessa M. Andrade, Tatyana Nery, Ana C. B. Alves, Aderbal A. Silva, Stephanie R. S. Carvalhal, Matheus F. Zazula, Katya Naliwaiko, Luiz C. Fernandes, Zsolt Radak, Ricardo A. Pinho
Summary: This study investigated the effects of physical training on behavior, redox balance, and genomic stability in models of aggressive brain cancer. The results showed that moderate aerobic exercise could have a beneficial impact on GBM treatment by improving behavior and reducing genomic instability.
Article
Polymer Science
E. Torres Zanoni, R. Benavides, L. Da Silva, M. D. Morales-Acosta, D. Morales-Acosta
Summary: Nitrogen-doped mesoporous carbon (N-MC) was prepared by pyrolysis of melamine-modified resorcinol-formaldehyde (RF) resin, and used as a support of Pd nanoparticles for formic acid electro-oxidation reaction (FAOR). The study found that N-MC obtained from resins with higher melamine concentration exhibited higher graphitic crystallinity and deformed pores. TEM analysis showed better dispersion and smaller size of Pd nanoparticles for the catalysts supported on N-MC. The electrochemical evaluation confirmed that N-MC supported catalysts exhibited higher electrochemical surface area and higher catalytic activity towards FAOR than Pd/MC.
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
(2023)
Article
Multidisciplinary Sciences
Matheus s. Rodrigues, Julia n. Martins, Gabriela c. DE Paula, Ligia m. Venturini, Gustavo de b. Silveira, EMiLIO L. Streck, J. O. S. I. A. N. I. Budni, Ricardo a. machado DE Vila, Andreza f. DE Bem, Paulo c. l. Silveira, J. A. D. E. DE Oliveira
Summary: High cholesterol levels can cause oxidative stress in the liver and heart tissues, which can be partially alleviated by treatment with gold nanoparticles.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS
(2022)