期刊
APPLIED PHYSICS LETTERS
卷 103, 期 19, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.4827302
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资金
- National Scientific Equipment Development Special Foundation of China [2011YQ030134]
- Strategic Newly emerged Industry Development Special Foundation of Shenzhen
- National Natural Science Foundation of China [51376102]
- Independent Scientific Research Plan of China [2012Z01011]
A method of manufacturing three-dimension microneedle electrode arrays is presented in this paper using the micromolding technology with liquid metal at room temperature, based on the physical property of the Bi-In-Sn liquid metal alloy, being its melting point especially low. Observed under scanning electron microscopy, the needle body of the electrode chip manufactured using this method has a good consistency. Skin penetration test in-vitro indicates that the microneedle electrode can pierce the stratum corneum and cross the high-impedance layer to acquire electrical signals. Electrical impedance and polarization voltage experimental results show that the electrode chips have great electric characteristics and meet the practical application demands. (C) 2013 AIP Publishing LLC.
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