Article
Electrochemistry
Chunbo Qu, Jingyi Zhang, Lixin Na
Summary: A novel impedimetric immunosensor using gold/polypyrrole-polydopamine nanocomposite as an immobilization matrix was fabricated for the detection of CEA. The sensor showed a wide linear range, low detection limit, high specificity, and excellent reproducibility and stability, providing experimental evidence for early cancer diagnosis.
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
(2022)
Article
Optics
Ram Bilash Choudhary, Debashish Nayak
Summary: Integrating semi-conductive materials into the polypyrrole (PPy) matrix effectively enhances PPy's properties. The laboratory-synthesized rGO-PPyZnS (rPZ) nanocomposites exhibit high rate of electron-hole recombination and surface conductivity, making them suitable for use as an emissive layer in OLED devices.
Article
Chemistry, Physical
Jingwen Feng, Maocheng Jiang, Dong Li, Yuanming Zhang, Chen Pei, Li Zhou, Zhuo Chen, Yanzhao Li, Xinguo Li, Xiaoguang Xu
Summary: Researchers have successfully developed a high-performance, heavy metal-free quantum dot light-emitting diode for eco-friendly displays. By adjusting the ratio of Te/Se in the core, they were able to create blue quantum dots with adjustable energy levels and emission peaks. By optimizing the microcavity structure and electrical properties, they achieved a chroma efficiency of 72 for the blue devices, which is 2.2 times higher than the control device.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Xue Bai, Finn Purcell-Milton, Yurii K. Gun'ko
Summary: Cu-Based quantum dots are being explored as a potential replacement for toxic Cd- or Pb-based QDs, with studies focusing on the impact of different reaction conditions on the resulting morphologies and optical properties. By carefully controlling the ZnS shell deposition, researchers have optimized the synthesis of CIZS/ZnS/ZnS QDs and produced highly fluorescent core/shell/shell heterostructured QDs with high PLQYs. Additionally, the successful creation of giant ZnS shell QDs opens up possibilities for further development in this area.
Article
Engineering, Chemical
Riya Gupta, Usisipho Feleni, Emmanuel Iwuoha
Summary: Prostate cancer is a major global threat, with PSA serving as a potential biomarker for early diagnosis. An extremely sensitive electrochemical immunosensor was developed with a detection limit of 0.36 ng/mL, making it suitable for clinical applications.
Article
Chemistry, Multidisciplinary
Haoyu Wang, Pengli Xiao, Shengbo Sang, Honglie Chen, Xiushan Dong, Yang Ge, Xing Guo, Dong Zhao
Summary: Abnormal HSA concentration levels are closely associated with renal disease status in clinical diagnosis. The surface stress biosensor has been developed to detect protein molecule concentration and has various clinical applications, but improved sensitivity is required. In this study, a multilayer heterogeneous membrane biosensor (MHBios) based on the coupling of magnetic field, electric field, and surface stress field was successfully developed for high sensitivity HSA detection. The MHBios showed a lower detection limit compared to the minimum diagnostic limit of microalbuminuria, indicating its potential for early disease screening.
Article
Biophysics
Jiao Ma, Xiaohui Mao, Hongxiao Cong, Xiaoting Li, Jing Sun, Meiling Wang, Hua Wang
Summary: The novel composite hydrogel proposed in this paper serves as a sensing and immobilizing substrate with excellent electrochemical properties and loading capacity. The optimized immunosensor demonstrates high sensitivity and a wide linear range for motilin detection, with low detection limits, making it applicable in practical diagnosis.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Physical
Aliaksandra Radchanka, Varvara Hrybouskaya, Andrey Iodchik, Alexander W. Achtstein, Mikhail Artemyev
Summary: In this study, the researchers found that by varying the surface charged groups on CdSe/ZnS QDs, the zeta-potential can be tuned to control the quantum yield of emission and the recombination dynamics. The presence of zwitterionic surface groups allows for pH tuning of the zeta-potential and quantum yield.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Spectroscopy
Ying Bao, Kexin Han, Zhifang Ding, Yue Li, Ting Li, Ming Guan, Guixin Li
Summary: Polypyrrole-luminol-AuNPs nanocomposites were prepared and utilized for a label-free electrochemiluminescence (ECL) immunosensor for detecting carbohydrate antigen 153 (CA153). The nanocomposites exhibited excellent ECL activity and good film-forming property, allowing them to be fixed on electrode surface without the need for additional film-forming materials.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biochemical Research Methods
Min Yin, Yan Wang, Xuwen Gao, Shichao Du, Yan Cheng, Shuai Yu, Guizheng Zou, Fumin Xue
Summary: A near-infrared electrochemiluminescence immunosensor was developed using AgInS2/ZnS nanocrystals as environmentally-friendly tags for sensitive and selective detection of CA125. The platform showed efficient detection capabilities with a detection limit of 1 x 10(-6) U/mL, offering potential for early diagnosis and treatment of ovarian cancer.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Anabel Laza, Ana Godoy, Sirley Pereira, Pedro R. Aranda, Carlos D. Garcia, Julio Raba, Franco A. Bertolino
Summary: A simple sensor for the determination of progesterone has been developed using a molecularly imprinted polymer. The sensor showed good linear response, selectivity, and stability, making it a promising alternative for analysis of progesterone.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Applied
Wen-jia Yin, Jing-xian Zhang, Hong Wang, Yu Wang, Xi Zeng, Zhen-lin Xu, Jin-yi Yang, Zhi-li Xiao, Bruce D. Hammock, Peng Wen
Summary: A sensitive and reliable electrochemical immunosensor based on cross-linked polyvinyl alcohol/citric acid nanofiber membrane (PVA/CA NFM) and horseradish peroxidase labeled anti-parathion nanobody was constructed for monitoring the residual of parathion pesticide in food. The immunosensor exhibited high specificity and sensitivity to parathion and showed good stability.
Article
Materials Science, Multidisciplinary
Lacey Reid, Wadood Y. Hamad
Summary: The study found that electroactive biopolymer hydrogels can be used as soft actuators for biomedicine and robotics, behaving as anionic polymer actuators. Incorporating CNCs into non-electroresponsive polyacrylamide can enhance the bending response and lifespan of the hydrogels.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Chemistry, Applied
Yanbo Wang, Junjie Ma, Huan Li, Jinru Zhou, Hong Zhang, Linglin Fu
Summary: A novel immunoassay for quantitation of shrimp arginine kinase (AK) was developed using gold nanoparticles and quantum dots, showing high sensitivity and specificity.
Article
Chemistry, Physical
Natalia Bielejewska, Robert Hertmanowski
Summary: This study focused on the preparation and properties of nanocomposite films based on liquid crystal and cellulose nanocrystals mixtures, aiming to combine the advantages of both components and create new quality. The studied systems showed different surface characteristics related to the intermolecular interactions between liquid crystals and cellulose nanocrystals.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Multidisciplinary
Sudhir Kumar Sharma, Sumaya Al Hosani, Mona Kalmouni, Anjana Ramdas Nair, Loganathan Palanikumar, Renu Pasricha, Kirsten C. Sadler, Mazin Magzoub, Ramesh Jagannathan
Review
Polymer Science
Sarita S. Nair, Sujeet K. Mishra, D. Kumar
Summary: The review highlights the impressive electrochemical performance improvement of advanced polymeric materials in energy conversion and storage devices, emphasizing the significance of advanced-nanostructured materials such as carbon-based nanomaterials, metal-organic frameworks. It showcases the key strategies involved in the technological usage of polymeric materials for designing and fabricating energy devices like solar cells, supercapacitors, batteries, and fuel cells, while also addressing the remaining challenges and future prospects.
POLYMER-PLASTICS TECHNOLOGY AND MATERIALS
(2021)
Article
Multidisciplinary Sciences
L. Palanikumar, Laura Karpauskaite, Mohamed Al-Sayegh, Ibrahim Chehade, Maheen Alam, Sarah Hassan, Debabrata Maity, Liaqat Ali, Mona Kalmouni, Yamanappa Hunashal, Jemil Ahmed, Tatiana Houhou, Shake Karapetyan, Zackary Falls, Ram Samudrala, Renu Pasricha, Gennaro Esposito, Ahmed J. Afzal, Andrew D. Hamilton, Sunil Kumar, Mazin Magzoub
Summary: This study successfully identifies a small molecule that can inhibit the aggregation of mutant p53 protein and restore its function, leading to inhibition of cancer cell proliferation and tumor growth.
NATURE COMMUNICATIONS
(2021)
Article
Engineering, Electrical & Electronic
Hizb Ullah Khan, Muhammad Tariq, Mutabar Shah, Sajid Ullah, Abdul Razaq Ahsan, Abdur Rahim, Jibran Iqbal, Renu Pasricha, Issam Ismail
Summary: In this research, a highly sensitive and stable capacitive humidity sensor based on PVP/WO3 nanocomposite was successfully developed. The sensor showed a high response of 44.73 nF/%RH, short response time (10 s) and recovery time (15 s), along with low hysteresis and excellent stability and repeatability.
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
(2021)
Article
Pharmacology & Pharmacy
Nahid S. Awad, Mohamed Haider, Vinod Paul, Nour M. AlSawaftah, Jayalakshmi Jagal, Renu Pasricha, Ghaleb A. Husseini
Summary: The study successfully encapsulated hydrophilic graphene quantum dots in stealth liposomes and triggered their release using low-frequency ultrasound, providing an effective method to deliver QDs to tumor cells while reducing systemic toxicity.
Review
Chemistry, Multidisciplinary
Jyotika Grewal, Vijay Kumar, Hemant Rawat, Yashika Gandhi, Ravindra Singh, Arjun Singh, Gajji Babu, Narayanam Srikanth, Sujeet K. Mishra
Summary: This article presents the synthesis of metal nanoparticles using medicinal plant extracts and examines their toxicity to cancer cells. The anticancer effect of these nanoparticles is explained through several possible mechanisms, including the generation of reactive oxygen species, cell cycle arrest, antioxidant property, apoptosis, and autophagy. Plant compounds that induce cytotoxicity against cancer cells and assays for measuring cell toxicity are also discussed.
ENVIRONMENTAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Analytical
Vijay Kumar, Vikram Kushwaha, Yashika Gandhi, Sujeet K. Mishra, Vaibhav Charde, Chandrashekhar Jagtap, G. Babu, Arjun Singh, Ravindra Singh, Narayanam Srikanth
Summary: A new, simple, selective, sensitive, precise, and robust high-performance thin-layer chromatography (HPTLC) method was developed and validated for the simultaneous quantification of 6-gingerol, guggulsterone E, and guggulsterone Z in coded formulation AYUSH SG-5 (for rheumatoid arthritis).
JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC
(2022)
Article
Plant Sciences
Vijay Kumar, Vikram Kushwaha, Vaibhav Charde, Chandrashekar Jagtap, Yashika Gandhi, Jyotika Grewal, Ravi Verma, Hemant Rawat, Sujeet K. Mishra, Akanksha Thakur, G. Babu, Arjun Singh, Ravindra Singh, Narayanam Srikanth, K. S. Dhiman
Summary: Ayurvedic medicine holds significant importance and dominance in the Indian Medicine System. However, the lack of standardization of herbal drugs has hindered the recognition of India's traditional medicine system. Standardization plays a crucial role in assessing the quality, purity, efficacy, potency, and safety of herbal drugs. Recent guidelines from the World Health Organization and European Medicines Agency aim to address the quality control of herbal drugs. This study focuses on the standardization of a coded poly-herbal tablet formulation and proposes a monograph for its quality control. The research provides valuable insights for pharmacists in formulating the product and can serve as a pharmaceutical standard operating procedure.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Article
Multidisciplinary Sciences
Gobinda Das, Bikash Garai, Thirumurugan Prakasam, Farah Benyettou, Sabu Varghese, Sudhir Kumar Sharma, Felipe Gandara, Renu Pasricha, Maria Baias, Ramesh Jagannathan, Na'il Saleh, Mourad Elhabiri, Mark A. Olson, Ali Trabolsi
Summary: Ionic covalent organic frameworks (iCOFs) are porous materials with great potential for various applications. Functionalized iCOFs can be used as chemosensors for amine detection with high sensitivity, for example, to monitor meat spoilage.
NATURE COMMUNICATIONS
(2022)
Review
Nanoscience & Nanotechnology
Gobinda Das, Tina Skorjanc, Thirumurugan Prakasam, Bikash Garai, Salma Abubakar, Christina Saad Zalch, Felipe Gandara, Renu Pasricha, Sudhir Kumar Sharma, Sabu Varghese, Ramesh Jagannathan, Mark A. Olson, Ali Trabolsi
Summary: Accidental oil spills cause severe damage to marine and coastal ecosystems, making the development of efficient cleaning materials crucial. In this study, we report the rapid synthesis of two structurally similar covalent organic frameworks (COFs) using microwave-assisted methods. One COF exhibited a spherical sea urchin-like morphology and was hydrophilic, while the other COF had a bowl-shaped hollow spherical structure and was hydrophobic. Surface modification with a thioanisole moiety enhanced the hydrophobicity of the COF. The TAB-MPPD COF showed excellent oil removal performance for various types of oils.
ACS APPLIED NANO MATERIALS
(2022)
Article
Developmental Biology
Arpitha Rao, Guruprasad Nayak, Hanumappa Ananda, Sandhya Kumari, Rahul Dutta, Sneha Guruprasad Kalthur, Srinivas Mutalik, Sneha Ann Thomas, Renu Pasricha, Shamprasad Varija Raghu, Satish Kumar Adiga, Guruprasad Kalthur
Summary: The study found that ATDs administration to mice resulted in prolonged estrous cycles, reduced ovarian follicle reserve, altered hormone levels, decreased number of ovulated oocytes, and potential adverse effects on cytoplasmic organization of oocytes.
REPRODUCTION FERTILITY AND DEVELOPMENT
(2022)
Article
Nanoscience & Nanotechnology
Sudhir Kumar Sharma, Renu Pasricha, James Weston, Thomas Blanton, Ramesh Jagannathan
Summary: In this study, a technique to synthesize free-standing, one-atom thick 2D gold crystals (goldene) and self-assembled 2D periodic arrays of goldene was reported. The goldene exhibited unique lattice structures and magnetic properties, confirming its two-dimensionality.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Physical
Mohamed Haider, Roberta Cagliani, Jayalakshmi Jagal, Manju N. Jayakumar, Bahgat Fayed, Sarra B. Shakartalla, Renu Pasricha, Khaled Greish, Raafat El-Awady
Summary: This study aimed to develop a targeted nanotheranostic agent for early diagnosis and inhibition of malignant progression in colorectal cancer. Covalently labeled graphene oxide quantum dots showed increased targeting and specific uptake in colorectal cancer cells expressing the PLAC-1 antigen, leading to enhanced cell cytotoxicity and reduced invasiveness. This highlights the potential use of these targeted nanoparticles for detection and treatment of colorectal cancer.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Astronomy & Astrophysics
Laura Manenti, Umang Mishra, Gianmarco Bruno, Henry Roberts, Panos Oikonomou, Renu Pasricha, Isaac Sarnoff, James Weston, Francesco Arneodo, Adriano Di Giovanni, Alexander John Millar, Knut Dundas Mora
Summary: We report the results of a search for dark photons using a multilayer dielectric haloscope. No significant signal excess is observed, setting exclusion limits on the coupling constant between dark photons and ordinary photons.
Article
Chemistry, Multidisciplinary
Farah Benyettou, Nawel Kaddour, Thirumurugan Prakasam, Gobinda Das, Sudhir Kumar Sharma, Sneha Ann Thomas, Fadia Bekhti-Sari, Jamie Whelan, Mohammed A. Alkhalifah, Mostafa Khair, Hassan Traboulsi, Renu Pasricha, Ramesh Jagannathan, Nassima Mokhtari-Soulimane, Felipe Gandara, Ali Trabolsi
Summary: This study introduces a novel approach using nCOF nanoparticles for oral insulin delivery, which demonstrated protection of insulin and glucose-responsive release in vitro, as well as hyperglycemia-induced release in vivo without toxic effects in diabetic rats. These findings suggest that nCOF-based oral insulin delivery systems could potentially replace traditional subcutaneous injections for insulin therapy.
