4.6 Article

Multimodal coherent anti-Stokes Raman spectroscopic imaging with a fiber optical parametric oscillator

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APPLIED PHYSICS LETTERS
卷 98, 期 19, 页码 -

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AMER INST PHYSICS
DOI: 10.1063/1.3589356

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  1. Air Force Office of Scientific Research (AFOSR) [FA955009-1-0483]
  2. National Institute of Health (NIH) [R01 EB 7243]

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We report on multimodal coherent anti-Stokes Raman scattering (CARS) imaging with a source composed of a femtosecond fiber laser and a photonic crystal fiber (PCF)-based optical parametric oscillator (FOPO). By switching between two PCFs with different zero dispersion wavelengths, a tunable signal beam from the FOPO covering the range from 840 to 930 nm was produced. By combining the femtosecond fiber laser and the FOPO output, simultaneous CARS imaging of a myelin sheath and two-photon excitation fluorescence imaging of a labeled axons in rat spinal cord have been demonstrated at the speed of 20 mu s per pixel. (C) 2011 American Institute of Physics. [doi:10.1063/1.3589356]

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