Article
Engineering, Electrical & Electronic
T. Mansuryan, A. Tonello, K. Krupa, A. Desmouliere, G. Ndong Ntoutoume, V. Sol, C. Lefort, M. Zitelli, M. Ferraro, F. Mangini, Y. Sun, Y. Arosa Lobato, B. Wetzel, S. Wabnitz, V. Couderc
Summary: This paper demonstrates the spatial multiplexing of a narrowband pump and a broadband spectrum in a few-mode microstructure fiber by selectively coupling them in two different modes. One mode preserves the narrow bandwidth of the pump while the other mode experiences spectral broadening. Bimodal propagation is achieved by maximizing the coupling into the fundamental mode of the fiber. The combined output beam is used for self-referenced multiplex coherent anti-Stokes Raman scattering micro-spectroscopy.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Shamsul Abedin, Yong Li, Abid Anjum Sifat, Khokan Roy, Eric O. Potma
Summary: This study addresses the challenges of stability and reproducibility in surface-enhanced coherent anti-Stokes Raman scattering (SE-CARS) by using nanoantennas made from high-index dielectric particles. The experimental results demonstrate enhanced molecular CARS signals observed at Si nanoantennas, which offer improved thermal stability compared to metallic counterparts.
Article
Optics
Niklas M. Luepken, Thomas Wuerthwein, Klaus-J Boller, Carsten Fallnich
Summary: Tunable waveguide-based optical parametric amplification by four-wave mixing (FWM) in silicon nitride waveguides is presented, showing the potential for generating signal and idler pulses with different wavelengths for CARS imaging.
Article
Optics
Danni Chen, Zhengyi Liu, Shuanglong Liu, Hanben Niu
Summary: This article demonstrates three-color ultrabroadband CARS spectroscopy based on a single fiber laser. A supercontinuum with a wide bandwidth of 780-1240 nm is generated in a simple manner, allowing real-time capture of CARS signals in most of the fingerprint range.
OPTICS COMMUNICATIONS
(2022)
Article
Optics
Gwanjin Lee, Konkada Manattayil Jyothsna, Heejin Lim, Jonghoo Park, JaeDong Lee, Varun Raghunathan, Hyunmin Kim
Summary: In this study, a focus-engineered non-degenerate pumped coherent anti-Stokes Raman scattering (CARS) method using phase shaping, liquid lens focus control, and confocal detection is proposed for resolving non-fluorescent samples beyond the diffraction limit. The results show that non-degenerate pumped CARS achieved approximately 75% improvement in resolution compared to degenerate CARS.
OPTICS AND LASERS IN ENGINEERING
(2022)
Article
Materials Science, Multidisciplinary
Peng Lei, Xin Ding, Yuntao Bai, Xuanyi Yu, Guoxin Jiang, Tengteng Li, Bing Sun, Xingrui Zhang, Xiangxiang Li, Liang Wu, Guizhong Zhang, Jianquan Yao
Summary: The study demonstrated an efficient MgO:PPLN singly resonant optical parametric oscillator pumped by a Nd:YVO4/YVO4 laser, achieving high conversion efficiency and output power with excellent optical performance. The tuning range of the signal wave can be achieved by adjusting the crystal period.
RESULTS IN PHYSICS
(2021)
Article
Chemistry, Analytical
Georgi Petrov, Rajan Arora, Vladoslav V. Yakovlev
Summary: The study demonstrated chemical imaging of calcifications in tissues using long wavelength excitation, with imaging and analysis performed 2 mm below the skin level in a model system. Applications to breast cancer diagnostics and imaging were discussed, along with methods to extend depth and improve spatial resolution in chemical imaging.
Article
Multidisciplinary Sciences
Yujia Zhang, Minjian Lu, Zhendong Zhu, Yan Li, Haoyun Wei
Summary: Based on the enhancement factor of broadband SECARS excitation process, a novel Fano resonance plasmonic nanostructure is studied, which shows significant enhancement effect in a wide wavenumber region, covering most of the fingerprint region. This geometrically-tunable Fano plasmonic nanostructure provides a way to realize broadband-enhanced CARS, with potentials in single-molecular monitoring and high-selectivity biochemical detection.
SCIENTIFIC REPORTS
(2023)
Article
Instruments & Instrumentation
Nao Hirai, Yasuhiro Maeda, Kosuke Hashimoto, Bibin B. Andriana, Hiroko Matsuyoshi, Hidetoshi Sato
Summary: The study introduces a new type of CARS instrument with a double-wavelength-emission, background-free, electronically tuned Ti:sapphire laser (DW-ETL), which can provide stable CARS spectra for biological applications by controlling each laser pulse emission throughout the fingerprint region.
APPLIED SPECTROSCOPY
(2021)
Article
Thermodynamics
Daniel R. Richardson, Sean P. Kearney, Daniel R. Guildenbecher
Summary: Accurate measurement of post-detonation fireball temperatures is crucial for understanding device performance. In this study, a hybrid fs-ps CARS instrument was used to measure temperatures in the fireball of a commercial detonator. Challenges such as light scattering from particulate matter and solid fragments were addressed using a new polarization scheme.
PROCEEDINGS OF THE COMBUSTION INSTITUTE
(2021)
Article
Engineering, Electrical & Electronic
Shun Takahashi, Jingwen Shou, Gaoyu Dai, Yasuyuki Ozeki
Summary: This study presents a widely wavelength-tunable fiber-based optical parametric oscillator (FOPO) using four-wave mixing in a photonic crystal fiber and an intracavity spectral filter. The FOPO is capable of generating nearly transform-limited pulses and has a tuning range between 832 and 922 nm. The synchronized FOPO with a low-noise picosecond laser is beneficial for sensitive and broadband vibrational imaging by stimulated Raman scattering microscopy.
IEEE PHOTONICS TECHNOLOGY LETTERS
(2022)
Article
Optics
Tong Wang, Junfeng Jiang, Kun Liu, Shuang Wang, Panpan Niu, Yize Liu, Tiegen Liu
Summary: We proposed and demonstrated a flexible, endoscopic, and minimally invasive method for coherent anti-Raman Stokes scattering (CARS) measurement in single-cell applications, using a tapered optical fiber probe. The experimental results showed that this tapered optical fiber probe can detect carbon-hydrogen (C-H) bond-rich substances and their concentration. This provides a potential solution for minimally invasive live-cell detection in the future.
Article
Instruments & Instrumentation
Runfeng Li, Ruijun Lan, Dashan Dong, Hong Yang, Kebin Shi
Summary: The Bessel beam CARS spectroscopic method enhances spectral fidelity and signal-to-noise ratio in a turbulent environment, improving the measurement accuracy.
APPLIED SPECTROSCOPY
(2023)
Article
Engineering, Electrical & Electronic
Honglin Ji, Jingchi Li, Xingfeng Li, Shuangyu Dong, Zhaopeng Xu, Yikai Su, William Shieh
Summary: This paper proposes a complementary polarization-diversity coherent receiver (C-PDCR) using remote LO, which enables rapid polarization tracking. Experimental results demonstrate the significant improvement achieved by this method under high-speed polarization rotation rates.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Lei Ouyang, Tobias Meyer-Zedler, Kel-Meng See, Wei-Liang Chen, Fan-Cheng Lin, Denis Akimov, Sadaf Ehtesabi, Martin Richter, Michael Schmitt, Yu-Ming Chang, Stefanie Grafe, Jurgen Popp, Jer-Shing Huang
Summary: This study investigates the enhancement effect of plasmonic gratings in nonlinear surface-enhanced coherent anti-Stokes Raman scattering (SECARS) using the platform of plasmonic Doppler grating (PDG). The PDGs spatially separate the input and output enhancement, allowing for observation and comparison of overall enhancement from different combinations of individual input and output beams. The results indicate that enhancement in the pump and anti-Stokes beams plays a more critical role in the overall enhancement than that in the Stokes beam.
Article
Multidisciplinary Sciences
Delong Zhang, Chen Li, Chi Zhang, Mikhail N. Slipchenko, Gregory Eakins, Ji-Xin Cheng
Article
Biochemical Research Methods
Delong Zhang, Wei Chen, Huan Chen, Han-Qing Yu, Ghassan Kassab, Ji-Xin Cheng
JOURNAL OF BIOPHOTONICS
(2018)
Article
Chemistry, Physical
Yeran Bai, Delong Zhang, Chen Li, Cheng Liu, Ji-Xin Cheng
JOURNAL OF PHYSICAL CHEMISTRY B
(2017)
Article
Chemistry, Physical
Hyeon Jeong Lee, Delong Zhang, Ying Jiang, Xiangbing Wu, Pei-Yu Shih, Chien-Sheng Liao, Brittani Bungart, Ciao-Ming Xu, Ryan Drenan, Edward Bartlett, Ji-Xin Cheng
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2017)
Article
Chemistry, Analytical
Xiaojie Li, Delong Zhang, Yeran Bai, Weibiao Wang, Jingqiu Liang, Ji-Xin Cheng
ANALYTICAL CHEMISTRY
(2019)
Article
Multidisciplinary Sciences
Yeran Bai, Delong Zhang, Lu Lan, Yimin Huang, Kerry Maize, Ali Shakouri, Ji-Xin Cheng
Article
Optics
Delong Zhang, Lu Lan, Yeran Bai, Hassaan Majeed, Mikhail E. Kandel, Gabriel Popescu, Ji-Xin Cheng
LIGHT-SCIENCE & APPLICATIONS
(2019)
Article
Engineering, Electrical & Electronic
Anton D. Shutov, Joseph T. Harrington, Hanlin Zhu, Da-Wei Wang, Delong Zhang, Vladislav V. Yakovlev
Summary: Raman spectroscopy provides a non-invasive, chemically-specific optical imaging of biological objects without using endogenous labels. Nonlinear Raman spectroscopy allows faster imaging with improved spatial resolution and axial sectioning capability. The report introduces a novel use of nonlinear Raman spectroscopy as a sensor of local nano-environment, where time-resolved coherent anti-Stokes Raman spectrograms are sensitive to small variations in local structural changes not normally observed with conventional Raman spectroscopy.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2021)
Article
Nanoscience & Nanotechnology
Weiru Fang, Tianrun Chen, Eddie Gil, Shiyao Zhu, Vladislav Yakovlev, Da-Wei Wang, Delong Zhang
Summary: Wavefront sensing and reconstruction are widely used in various applications including adaptive optics and high-resolution imaging. A novel nonlinear optical encoding method using optical second harmonic generation has been developed to enhance phase imaging sensitivity and efficiency. By utilizing deep neural networks, the method demonstrates efficient phase retrieval with high robustness.
Article
Chemistry, Analytical
Hanlin Zhu, Chenran Xu, Da-Wei Wang, Vladislav V. Yakovlev, Delong Zhang
Summary: Molecular vibrational spectroscopy is a widely used technique for sensing and imaging applications. This study developed a novel coherent Raman spectroscopy platform to investigate the temporal evolution of molecular vibrational dephasing.
ANALYTICAL CHEMISTRY
(2022)
Article
Optics
Weiru Fan, Tianrun Chen, Xingqi Xu, Ziyang Chen, Huizhu Hu, Delong Zhang, Da-Wei Wang, Jixiong Pu, Shi-Yao Zhu
Summary: Optical phase is crucial for biomedical imaging and astronomical observation, but it is often obscured by scattering media. Current methods are limited in retrieving phases at different depths. To address this challenge, a speckle three-dimensional reconstruction network (STRN) is developed to simultaneously extract multiple phase objects at different depths with high fidelity from speckle patterns.
LASER & PHOTONICS REVIEWS
(2022)
Proceedings Paper
Optics
Pengcheng Fu, Tianrun Chen, Hanlin Zhu, Chenran Xu, Ming Chen, Delong Zhang
ADVANCED OPTICAL IMAGING TECHNOLOGIES III
(2020)
Proceedings Paper
Engineering, Biomedical
Anton Shutov, Georgi Petrov, Delong Zhang, Vladislav V. Yakovlev
LABEL-FREE BIOMEDICAL IMAGING AND SENSING (LBIS) 2020
(2020)
Proceedings Paper
Optics
Delong Zhang, Ji-Xin Cheng
30TH ANNUAL CONFERENCE OF THE IEEE PHOTONICS SOCIETY (IPC)
(2017)
Article
Chemistry, Analytical
Chen Li, Delong Zhang, Mikhail N. Slipchenko, Ji-Xin Cheng
ANALYTICAL CHEMISTRY
(2017)