期刊
APPLIED PHYSICS LETTERS
卷 93, 期 1, 页码 -出版社
AMER INST PHYSICS
DOI: 10.1063/1.2956679
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资金
- NIBIB NIH HHS [R33 EB000778] Funding Source: Medline
We present real-time detection of airborne Vaccinia viruses using quartz crystal microbalance (QCM) in an integrated manner. Vaccinia viruses were aerosolized and neutralized using an electrospray aerosol generator, transported into the QCM chamber, and captured by a QCM crystal. The capture of the viruses on the QCM crystal resulted in frequency shifts proportional to the number of viruses. The capture rate varied linearly with the concentration of initial virus suspensions (8.5 x 10(8)-8.5 x 10(10) particles/ml) at flow rates of 2.0 and 1.1 l/min. This work demonstrates the general potential of mass sensitive detection of nanoscale biological entities in air. (C) 2008 American Institute of Physics.
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