High expression of a plectasin-derived peptide NZ2114 in Pichia pastoris and its pharmacodynamics, postantibiotic and synergy against Staphylococcus aureus

Design, expression, and characterization of a novel targeted plectasin against methicillin-resistant Staphylococcus aureus

(2012) Ruoyu Mao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

In vitro synergy, pharmacodynamics, and postantibiotic effect of 11 antimicrobial agents against Rhodococcus equi

(2012) Steeve Giguère et al.   VETERINARY MICROBIOLOGY

Efficacy of NZ2114, a Novel Plectasin-Derived Cationic Antimicrobial Peptide Antibiotic, in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus aureus

(2011) Yan Q. Xiong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The characteristic region of arenicin-1 involved with a bacterial membrane targeting mechanism

(2011) Jaeyong Cho et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Road to clinical efficacy: challenges and novel strategies for antimicrobial peptide development

(2011) Randal Eckert   Future Microbiology

Genotypes and Toxin Gene Profiles of Staphylococcus aureus Clinical Isolates from China

(2011) Yanping Xie et al.   PLoS One

Expression of plectasin in Pichia pastoris and its characterization as a new antimicrobial peptide against Staphyloccocus and Streptococcus

(2011) Jun Zhang et al.   PROTEIN EXPRESSION AND PURIFICATION

Engineering of protein secretion in yeast: strategies and impact on protein production

(2010) Alimjan Idiris et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

(2010) K. S. Brinch et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Molecular epidemiology of community-associated meticillin-resistant Staphylococcus aureus in Europe

(2010) Jonathan A Otter et al.   LANCET INFECTIOUS DISEASES

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

In Vivo Pharmacodynamic Characterization of a Novel Plectasin Antibiotic, NZ2114, in a Murine Infection Model

(2009) D. Andes et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High Cerebrospinal Fluid (CSF) Penetration and Potent Bactericidal Activity in CSF of NZ2114, a Novel Plectasin Variant, during Experimental Pneumococcal Meningitis

(2009) C. Ostergaard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

High-Level Expression and Novel Antifungal Activity of Mouse Beta Defensin-1 Mature Peptide in Escherichia coli

(2009) Yueling Wang et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Expression of antimicrobial peptide LH multimers in Escherichia coli C43(DE3)

(2009) Zi-gang Tian et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Vancomycin in Combination with Other Antibiotics for the Treatment of Serious Methicillin‐ResistantStaphylococcus aureusInfections

(2009) Stan Deresinski   CLINICAL INFECTIOUS DISEASES

Antibacterial activities of a fosfomycin/tobramycin combination: a novel inhaled antibiotic for bronchiectasis

(2009) D. L. MacLeod et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Limitations of antibiotic options for invasive infections caused by methicillin-resistant Staphylococcus aureus: is combination therapy the answer?

(2009) H. M. Nguyen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Identification and characterization of a novel antibacterial peptide, avian β-defensin 2 from ducks

(2009) Deying Ma et al.   JOURNAL OF MICROBIOLOGY

Postantibiotic Effect of Tigecycline against 14 Gram-Positive Organisms

(2008) G. A. Pankuch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Plectasin has antibacterial activity and no affect on cell viability or IL-8 production

(2008) Shintaro Hara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression, purification and structural studies of a short antimicrobial peptide

(2008) Mateja Zorko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Antimicrobial peptides effectively kill a broad spectrum of Listeria monocytogenes and Staphylococcus aureus strains independently of origin, sub-type, or virulence factor expression

(2008) Caroline Gottlieb et al.   BMC MICROBIOLOGY