Article
Biotechnology & Applied Microbiology
Ye Li, Hui Feng, Lihua Jin, Xiulan Xin, Qipeng Yuan
Summary: A new vector-based RNAi method using the mouse U6 promoter to express shRNA in filamentous fungi was developed and evaluated. The results suggest that the mouse U6 promoter may serve as a novel tool for RNAi induction in filamentous fungi. This study provides insights into the potential of utilizing shRNA vectors driven by the mouse U6 promoter for RNAi in fungi.
BIOTECHNOLOGY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Tianyi Wang, Yaming Zhang, Yuwei Liu, Yi Huang, Weiping Wang
Summary: This study demonstrates that under amino acid starvation, macropinocytosis and ubiquitin-proteasome system are activated as a nutrient supply route. Therefore, amino acid deprivation also sensitizes cancer cells to proteasome inhibition. By blocking macropinocytosis and proteasome simultaneously, an innovative approach is presented to exacerbate amino acid starvation in cancer therapy. A pH-responsive polymersome nanocarrier is developed to maximize therapeutic efficacy and minimize systemic side effects.
Article
Biology
Laura N. Balarezo-Cisneros, Soukaina Timouma, Alistair Hanak, Andrew Currin, Fernando Valle, Daniela Delneri
Summary: Kazachstania bulderi is a non-conventional yeast species with the ability to efficiently grow on glucose and d-gluconolactone at low pH. With a high-quality phased genome assembly, this reference genome provides valuable information for further research on biotechnologically relevant non-conventional yeasts and the development of genetic tools for manipulating them as production hosts in biotechnological processes.
COMMUNICATIONS BIOLOGY
(2023)
Review
Food Science & Technology
Miriam Regina Canesin, Cinthia Bau Betim Cazarin
Summary: Bread is a staple food in the human diet, and the bakery process involves the study of microbiological, nutritional, and technological aspects to improve the nutritional quality of bread products. Through the fermentation process, bread can have increased nutrient bioaccessibility and beneficial effects on consumer health.
CURRENT OPINION IN FOOD SCIENCE
(2021)
Article
Cell Biology
Vikramjit Lahiri, Shree Padma Metur, Zehan Hu, Xinxin Song, Muriel Mari, Wayne D. Hawkins, Janakraj Bhattarai, Elizabeth Delorme-Axford, Fulvio Reggiori, Daolin Tang, Joern Dengjel, Daniel J. Klionsky
Summary: This study reveals that subtle changes in nutrient availability can have a significant impact on autophagy flux through unknown post-transcriptional regulatory mechanisms affecting the expression of key autophagy-inducing kinase. The identification of two novel post-transcriptional regulators further highlights the complexity of autophagy regulation.
Article
Agriculture, Multidisciplinary
Tatiana Antipova, Valentina Zhelifonova, Kirill Zaitsev, Alexander Zherebker, Boris Baskunov, Yuri F. Oprunenko
Summary: Natural food colorants have gained much attention due to the increasing demand for healthy and safe food. This study discovered a red pigment and monasnicotinic acid (MNA) in the culture fluid extract of the fungus Aspergillus cavernicola VKM F-906. The structure of the pigment corresponded to cis-cavernamine (red pigment, RP), which exhibited rapid equilibrium between NH and OH forms in solution. In vitro experiments showed that MNA was synthesized from RP through chemical transformations without enzymatic participation. The culture broth extract and MNA exhibited antifungal activity against Fusarium fungi.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Cell Biology
Ying Zhou, Jian Guo, Xinyu Wang, Yang Cheng, Jianwen Guan, Priyam Barman, Ming-An Sun, Yuanyuan Fu, Wanhong Wei, Congjing Feng, Mary A. Lilly, Youheng Wei
Summary: The study identified multiple pathways regulating the expression of the GATOR1 component Nprl3 in Drosophila, and highlighted the crucial role of FKBP39 in controlling cellular metabolism.
CELL DEATH & DISEASE
(2021)
Review
Biotechnology & Applied Microbiology
Lulu Chang, Haiqin Chen, Xin Tang, Jianxin Zhao, Hao Zhang, Yong Q. Chen, Wei Chen
Summary: Mortierella alpina, an oleaginous filamentous fungus, is used for industrial production of arachidonic acid due to its high lipid productivity. Understanding its metabolic characteristics and key factors governing lipid biosynthesis is essential to enhance its industrial performance. Optimisation of fermentation and metabolic engineering are key strategies to improve lipid yield.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Food Science & Technology
Tingting Song, Zuofa Zhang, Qunli Jin, Weilin Feng, Yingyue Shen, Lijun Fan, Weiming Cai
Summary: Sanghuangporus sanghuang (SS) can be fermented on various grains to enhance nutritional composition and antioxidant activities. Oats are found to be one of the best substrates for SS fermentation, showing improved antioxidant properties.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2021)
Article
Food Science & Technology
Shuai Liu, Yuhao Li, Xiaoxiao Song, Xiaoyi Hu, Yuxin He, Junyi Yin, Shaoping Nie, Mingyong Xie
Summary: This study investigated the changes in volatile and nutrient compounds of mango juice fermentation by different strains of lactic acid bacteria. The results showed that fermentation could enhance the aroma of mango juice and reduce the levels of nitrite and carotenoids. Different strains of lactic acid bacteria had varying effects on the aroma of the juice. Further research is needed to understand the fermentation mechanisms.
Article
Green & Sustainable Science & Technology
Abba Nabayi, Christopher Teh Boon Sung, Ali Tan Kee Zuan, Tan Ngai Paing
Summary: This study aimed to investigate the effect of fermenting washed rice water (WRW) on bacterial population and nutrient composition. The results indicated that fermenting WRW can potentially increase plant growth and enhance soil health, particularly after 3 days of fermentation.
Article
Food Science & Technology
Marcela Aparecida Deziderio, Handray Fernandes de Souza, Eliana Setsuko Kamimura, Rodrigo Rodrigues Petrus
Summary: This study focused on the development of fermented beverages made from water-soluble extracts of oats, almonds, soybeans, Brazil nuts, and rice, and found that completely replacing dairy ingredients with water-soluble plant extracts could lead to the development of functional plant-based fermented beverages.
Article
Agriculture, Dairy & Animal Science
C. Liu, C. Wang, J. Zhang, Q. Liu, G. Guo, W. J. Huo, C. X. Pei, L. Chen, Y. L. Zhang
Summary: This study evaluated the effects of guanidinoacetic acid (GAA) and betaine (BT) on growth performance, nutrient digestion, and ruminal fermentation in bulls. The results showed that supplementing GAA or BT improved growth performance and feed efficiency, while also affecting ruminal pH and fermentation. However, combining GAA and BT did not have a further enhancing effect on bull performance compared to using GAA or BT alone.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Ilavenil Soundharrajan, Jeong Sung Jung, Karnan Muthusamy, Bae Hun Lee, Hyung Soo Park, Ravikumar Sivanesan, Ki Choon Choi
Summary: In this study, the anaerobic fermentation in triticale silage was improved by adding lactic acid bacteria (LAB). The LAB treatment resulted in a decrease in pH, an increase in lactic acid content, and a decrease in butyric acid content in the silage. Furthermore, the LAB treatment suppressed the growth of yeast and mold, enhancing the nutritional quality of the silage.
Article
Agriculture, Multidisciplinary
Yongjia Liu, Jing Zhang, Cong Wang, Gang Guo, Wenjie Huo, Chengqiang Xia, Lei Chen, Yawei Zhang, Caixia Pei, Qiang Liu
Summary: This study investigated the effects of different guanidinoacetic acid (GAA) supplementation levels on lactation performance, nutrient digestion, and ruminal fermentation in dairy cows. The results showed that supplementation of GAA improved milk performance and rumen fermentation in lactating dairy cows.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Biochemistry & Molecular Biology
Lydia Schmidt, Natalie Wielsch, Ding Wang, Wilhelm Boland, Antje Burse
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Mukesh Kumar Meena, Ramgopal Prajapati, Deepthi Krishna, Keerthi Divakaran, Yogesh Pandey, Michael Reichelt, M. K. Mathew, Wilhelm Boland, Axel Mithoefer, Jyothilakshmi Vadassery
Editorial Material
Biochemistry & Molecular Biology
Wilhelm Boland
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
(2019)
Article
Plant Sciences
Guanjun Li, Stefan Bartram, Huijuan Guo, Axel Mithoefer, Maritta Kunert, Wilhelm Boland
Article
Biochemistry & Molecular Biology
Guillermo H. Jimenez-Aleman, Marilia Almeida-Trapp, Gemma Fernandez-Barbero, Selena Gimenez-Ibanez, Michael Reichelt, Jyothilakshmi Vadassery, Axel Mithoefer, Julio Caballero, Wilhelm Boland, Roberto Solano
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
(2019)
Article
Chemistry, Multidisciplinary
Marcel Ritter, Vincensius S. P. Oetama, Daniel Schulze, Katrin Muetzlaff, Anja K. Meents, Raphael A. Seidel, Helmar Goerls, Matthias Westerhausen, Wilhelm Boland, Georg Pohnert
CHEMISTRY-A EUROPEAN JOURNAL
(2020)
Article
Biotechnology & Applied Microbiology
Sen Xie, Marine Vallet, Chao Sun, Maritta Kunert, Anja David, Xiancui Zhang, Bosheng Chen, Xingmeng Lu, Wilhelm Boland, Yongqi Shao
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2020)
Review
Biochemistry & Molecular Biology
Vincensius S. P. Oetama, Stefan Pentzold, Wilhelm Boland
Summary: Chlorophyll degradation in phytophagous insects may provide antimicrobial, antifungal, and antiviral effects when bound to certain proteins. These products not only offer nutritional value to insects but also provide protection against reactive oxygen species, benefiting both insects and humans.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
(2021)
Article
Plant Sciences
Mohammed Mahmood Sarheed, Fatemeh Rajabi, Maritta Kunert, Wilhelm Boland, Sascha Wetters, Kai Miadowitz, Andrzej Kazmierczak, Vaidurya Pratap Sahi, Peter Nick
FRONTIERS IN PLANT SCIENCE
(2020)
Article
Biochemistry & Molecular Biology
Tilottama Mazumdar, Beng Soon Teh, Aishwarya Murali, Wolfgang Schmidt-Heck, Yvonne Schlenker, Heiko Vogel, Wilhelm Boland
Summary: This study investigates the spatial and temporal changes of microbial communities in the larvae of the lepidopteran pest Spodoptera littoralis, as well as the survival strategies of the major gut bacterium E. mundtii in the larval gut.
JOURNAL OF CHEMICAL ECOLOGY
(2021)
Article
Plant Sciences
Oluwatosin Abdulsalam, Katharina Wagner, Sophia Wirth, Maritta Kunert, Anja David, Mario Kallenbach, Wilhelm Boland, Erika Kothe, Katrin Krause
Summary: The ectomycorrhizospheric habitat contains a diverse pool of organisms, including the host plant, mycorrhizal fungi, and other rhizospheric microorganisms. Different signaling molecules may influence the ectomycorrhizal symbiosis. The basidiomycete Tricholoma vaccinum has the potential to produce unique communication molecules for interaction with its coniferous host, Norway spruce.
Article
Multidisciplinary Sciences
Sophia Wirth, Katrin Krause, Maritta Kunert, Selina Broska, Christian Paetz, Wilhelm Boland, Erika Kothe
Summary: Wood inhabiting fungi release volatiles that play an important role in wood decomposition and have activity against other fungi and bacteria. The volatiles of Schizophyllum commune inhibit fungal growth and modify bacterial motility. The microbial community in the mycosphere of S. commune includes Actinobacteria, Proteobacteria, Pseudomonadaceae, Sphingomonadaceae, Erwiniaceae, Yersiniaceae and Mariprofundacea as the dominating families, as well as ascomycetes and basidiomycetes in the fungal community.
Article
Biochemistry & Molecular Biology
Oldokh Otgon, Suvd Nadmid, Christian Paetz, Hans-Martin Dahse, Kerstin Voigt, Stefan Bartram, Wilhelm Boland, Enkhmaa Dagvadorj
Summary: Phytochemical investigation of the ethanol extract of underground parts of Iris tenuifolia Pall. resulted in the discovery of five new compounds, including one with high antibacterial activity. In addition, a newly discovered isoflavone showed inhibitory effects against leukemia cells.
Article
Microbiology
Marycolette Ndidi Ezediokpu, Katrin Krause, Maritta Kunert, Dirk Hoffmeister, Wilhelm Boland, Erika Kothe
Summary: Tricholoma vaccinum is an ectomycorrhizal basidiomycete with high host specificity. It is capable of producing multiple sesquiterpenes during co-cultivation with its ectomycorrhizal partner tree, Picea abies. The production of certain compounds changes dynamically during mycorrhizal growth, indicating the involvement of specific biosynthesis genes.
Review
Biochemistry & Molecular Biology
Matias L. Giglio, Wilhelm Boland, Horacio Heras
Summary: This article provides an overview of animal egg toxins, analyzing their chemistry and biosynthesis trends and patterns. It identifies around 100 properly identified egg toxins in 188 species, distributed across 5 phyla. The article proposes a multiparametric classification system and emphasizes the origin, structure, function, and toxicity range of egg toxins, as well as the existence of aposematic coloration in toxic eggs. However, there is still a significant lack of information in this field.
NATURAL PRODUCT REPORTS
(2022)