期刊
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
卷 87, 期 3, 页码 965-970出版社
SPRINGER
DOI: 10.1007/s00253-010-2557-8
关键词
2,3-Butanediol; Klebsiella pneumoniae; Corncob molasses; Fermentation
资金
- Chinese National Program for High-Technology Research and Development [2006AA02Z244]
- Chinese National Natural Science Foundation [30770064]
- National Basic Research Program of China [2007CB707803]
Corncob molasses, a waste by-product in xylitol production, contains high concentrations of mixed sugars. In the present study, corncob molasses was used to produce 2,3-butanediol (BD) using Klebsiella pneumoniae SDM. This was the first report on the use of corncob molasses to produce bulk chemicals. Our results indicated that K. pneumoniae SDM can utilize various sugars contained in the corncob molasses in a preferential manner: glucose > arabinose > xylose. It was shown that high sugars concentration had an inhibitory effect on the cells growth and BD production. The maximum concentration of BD was 78.9 g/l after 61 h of fed-batch fermentation, giving a BD productivity of 1.3 g/l h and a yield of 81.4%. The present study suggests that the low-cost corncob molasses could be used as an alternative substrate for the production of BD by K. pneumoniae SDM, as well as a potential carbon source for production of other high-value chemicals.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据