Titer improvement of iso-migrastatin in selected heterologous Streptomyces hosts and related analysis of mRNA expression by quantitative RT–PCR

iso-Migrastatin, Migrastatin, and Dorrigocin Production in Streptomyces platensis NRRL 18993 Is Governed by a Single Biosynthetic Machinery Featuring an Acyltransferase-less Type I Polyketide Synthase

(2009) Si-Kyu Lim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lactimidomycin, Iso-migrastatin and Related Glutarimide-Containing 12-Membered Macrolides Are Extremely Potent Inhibitors of Cell Migration

(2009) Jianhua Ju et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineered production of iso-migrastatin in heterologous Streptomyces hosts

(2008) Zhiyang Feng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency

(2008) Jianhua Ju et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Migrastatin and analogues: New anti-metastatic agents

(2008) Sébastien Reymond et al.   COMPTES RENDUS CHIMIE

Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?

(2008) David J. Newman   JOURNAL OF MEDICINAL CHEMISTRY

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

(2008) Carlos Olano et al.   METABOLIC ENGINEERING

Bacterial Hosts for Natural Product Production

(2008) Haoran Zhang et al.   MOLECULAR PHARMACEUTICS