Production of tranilast [N-(3′,4′-dimethoxycinnamoyl)-anthranilic acid] and its analogs in yeast Saccharomyces cerevisiae

The anti-allergic compound tranilast attenuates inflammation and inhibits bone destruction in collagen-induced arthritis in mice

(2010) N Shiota et al.   BRITISH JOURNAL OF PHARMACOLOGY

Tranilast inhibits the growth and metastasis of mammary carcinoma

(2009) Rabindranath Chakrabarti et al.   ANTI-CANCER DRUGS

Chymase activity is closely related with plaque vulnerability in a hamster model of atherosclerosis

(2009) Tao Guo et al.   ATHEROSCLEROSIS

Dihydroavenanthramide D protects pancreatic β-cells from cytokine and streptozotocin toxicity

(2009) Na Lv et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates

(2009) Steven C. Zammit et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Topical tranilast for treatment of the early stage of mild dry eye associated with chronic GVHD

(2009) Y Ogawa et al.   BONE MARROW TRANSPLANTATION

Dermal and transdermal targeting of dihydroavenanthramide D using enhancer molecules and novel microemulsions

(2009) Sandra Heuschkel et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

In Vitro Antioxidant Activity and Antigenotoxic Effects of Avenanthramides and Related Compounds

(2009) Alison M. Lee-Manion et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Engineering Monolignol 4-O-Methyltransferases to Modulate Lignin Biosynthesis

(2009) Mohammad-Wadud Bhuiya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PAD1 and FDC1 are essential for the decarboxylation of phenylacrylic acids in Saccharomyces cerevisiae

(2009) Nobuhiko Mukai et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Metabolic engineering of the complete pathway leading to heterologous biosynthesis of various flavonoids and stilbenoids in Saccharomyces cerevisiae

(2009) Emmanouil Trantas et al.   METABOLIC ENGINEERING

Production of novel antioxidative phenolic amides through heterologous expression of the plant’s chlorogenic acid biosynthesis genes in yeast

(2009) Moglia Andrea et al.   METABOLIC ENGINEERING

Rectal administration of tranilast ameliorated acute colitis in mice through increased expression of heme oxygenase-1

(2009) Xiaomei Sun et al.   PATHOLOGY INTERNATIONAL

Expression of serotonin derivative synthetic genes on a single self-processing polypeptide and the production of serotonin derivatives in microbes

(2008) Munyoung Park et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages

(2008) Hyun-Ock Pae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reducing post-surgical adhesions utilizing a drug-enhanced device: sodium carboxymethylcellulose aqueous gel/poly(p-dioxanone) and Tranilast

(2008) Helen Cui et al.   Biomedical Materials

Modulation of Dihydroavenanthramide D release and skin penetration by 1,2-alkanediols

(2008) S HEUSCHKEL et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Radical-scavenging and antioxidant activity of avenanthramides

(2008) Amelie Fagerlund et al.   FOOD CHEMISTRY

Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production

(2008) Benedikt Engels et al.   METABOLIC ENGINEERING

Production of phenylpropanoid compounds by recombinant microorganisms expressing plant-specific biosynthesis genes

(2008) Ilef Limem et al.   PROCESS BIOCHEMISTRY

Avenanthramides, polyphenols from oats, inhibit IL-1β-induced NF-κB activation in endothelial cells

(2007) Weimin Guo et al.   FREE RADICAL BIOLOGY AND MEDICINE