Article
Biology
Digar Singh, Sang Hee Lee, Choong Hwan Lee
Summary: This study investigates the ecological interactions between Bacillus amyloliquefaciens and Aspergillus oryzae through a pairwise metabolite cross-feeding experiment. The results show that cross-feeding Aspergillus metabolites benefit the growth and biofilm formation of Bacillus, while cross-feeding Bacillus extracts suppress the mycelial growth and conidiation of Aspergillus.
COMMUNICATIONS BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ida Szmigiel, Dorota Kwiatkowska, Marcin Lukaszewicz, Anna Krasowska
Summary: This study found that using xylan and its derivatives from plant hemicellulose as substrates can promote efficient biosurfactant production by Bacillus subtilis, providing a new approach for the reutilization of agricultural residues.
Article
Biotechnology & Applied Microbiology
Mathieu Bouchard-Rochette, Younes Machrafi, Louis Cossus, Thi Thuy An Nguyen, Hani Antoun, Arnaud Droit, Russell J. Tweddell
Summary: Bacillus pumilus strain PTB180 and Bacillus subtilis strain PTB185 secrete lipopetides that have strong antagonistic activity against several plant pathogens, including Botrytis cinerea. These strains inhibit the mycelial growth and conidial germination of B. cinerea and can survive on tomato phyllosphere for at least 21 days. Foliar applications of these strains significantly reduce the incidence and severity of gray mold on tomato plants.
BIOLOGICAL CONTROL
(2022)
Article
Chemistry, Organic
Diana Gimenez, Aoife Phelan, Cormac D. Murphy, Steven L. Cobb
Summary: The synthesis of fengycin A analogues with enhanced antifungal properties and chemical stability under acidic and basic conditions is reported. The analogues show that the fengycin core structure can be modified and simplified without loss of antifungal activity.
Article
Biochemistry & Molecular Biology
Beata Koim-Puchowska, Grzegorz Klosowski, Joanna Maria Drozdz-Afelt, Dawid Mikulski, Alicja Zielinska
Summary: The study found that under suitable culture conditions, Bacillus subtilis natto BS19 can efficiently synthesize surfactin using starch as the carbon source and yeast extract as the nitrogen source. Potato peelings were proven to be an effective waste substrate, enhancing the biosynthesis of surfactin.
Article
Biotechnology & Applied Microbiology
Stephen Olusanmi Akintayo, Behnoush Hosseini, Maliheh Vahidinasab, Marc Messmer, Jens Pfannstiel, Ute Bertsche, Philipp Hubel, Marius Henkel, Rudolf Hausmann, Ralf T. Voegele, Lars Lilge
Summary: This study evaluated the biocontrol ability of two new B. velezensis strains, ES1-02 and EFSO2-04, against fungal phytopathogens Diaporthe spp. and compared with reference strains QST713 and FZB42. The results showed that all strains were effective against the plant pathogens, with the new strains showing comparable antifungal activity to QST713 and slightly lower activity than FZB42.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Peter Klausmann, Katja Hennemann, Mareen Hoffmann, Chantal Treinen, Moritz Aschern, Lars Lilge, Kambiz Morabbi Heravi, Marius Henkel, Rudolf Hausmann
Summary: Bacillus subtilis 3NA, a strain capable of high cell densities, utilized its surfactin-producing variant JABs32 in fed-batch processes to achieve significantly increased surfactin titers. Optimization of culture conditions showed a promising potential for enhanced surfactin production in high cell density fermentation.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Review
Food Science & Technology
Bo Zhang, Linlin Xu, Jinlin Ding, Mengze Wang, Rui Ge, Hongfei Zhao, Bolin Zhang, Junfeng Fan
Summary: This article reviews the potential and application of lipopeptides (LPs) formed by Bacillus spp. in food preservation. LPs have broad-spectrum antimicrobial activities and can effectively inhibit microbial spoilage of food, playing an important role in preserving the quality of vegetables, fruits, drinks, and aquatic products. In addition, the yield of LPs can be enhanced by gene regulation and the optimization of fermentation parameters, and nano-encapsulation of LPs holds promise for improving the preservation of food.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Plant Sciences
Yu Long, Shaoru Chen, Xiaochen Xu, Wenbao Zhao, Xinghao Tang, Lei Zhang, Qinghua Zhang
Summary: The endophytic bacterium N4, isolated from the healthy leaves of Phoebe bournei, demonstrates excellent biocontrol activity against stem canker caused by Lasiodiplodia theobromae in P. bournei. By assembling a high-quality genome of N4 using second- and third-generation sequencing methods, it was found that the N4 genome contains a circular DNA chromosome of 4,218,183 bp length with 43.5% GC content and 11 secondary metabolite biosynthesis gene clusters, including genes for subtilomycin synthesis. This high-quality genome assembly and gene annotation resource provide valuable insights into the biocontrol potential of B. subtilis strain N4 against stem canker in P. bournei.
Article
Biochemistry & Molecular Biology
Raguchander Thiruvengadam, Karthikeyan Gandhi, Sendhilvel Vaithiyanathan, Harish Sankarasubramanian, Karthiba Loganathan, Rajendran Lingan, Veera Ranjani Rajagopalan, Raveendran Muthurajan, Jonathan Ebenezer Iyadurai, Prabakar Kuppusami
Summary: Plant growth-promoting rhizobacteria (PGPR), especially Bacillus sp., are beneficial bacteria and widely used as biocontrol agents. In this study, the genome complexity of the potential biocontrol agent Bacillus subtilis Bbv57 was explored, revealing the presence of antimicrobial secondary metabolites.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biotechnology & Applied Microbiology
Michal Bochynek, Agnieszka Lewinska, Maciej Witwicki, Agnieszka Debczak, Marcin Lukaszewicz
Summary: In this study, we comprehensively characterized surfactin, a cyclic lipopeptide produced by Bacillus subtilis. We investigated its production, purified the homologues (C-12, C-13, C-14, C-15), and studied their physicochemical properties. We found a relationship between the structure and properties of surfactin, providing valuable insights for understanding its biological significance and potential applications in various industries. The methodology developed in this study can also be applied to other cyclic lipopeptides, facilitating a better understanding of their structure-properties relationship.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Biophysics
Mareen Hoffmann, Denise Mueck, Lutz Grossmann, Lena Greiner, Peter Klausmann, Marius Henkel, Lars Lilge, Jochen Weiss, Rudolf Hausmann
Summary: Surfactin, a biosurfactant produced by Bacillus subtilis, exhibits high interfacial activity and emulsion forming properties, making it a strong candidate for O/W emulsification. It is stable within the pH range of 6 to 9, but destabilizes with CaCl2 addition (>3mM).
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Agronomy
Yanjie Yi, Pengyu Luan, Shifei Liu, Youtian Shan, Zhipeng Hou, Shuyun Zhao, Shao Jia, Ruifang Li
Summary: The study demonstrates that the biocontrol agent Bacillus subtilis XZ18-3 can inhibit the growth of Rhizoctonia cerealis and cause cellular damage. A wettable powder formulation of B. subtilis XZ18-3 effectively controls the pathogen, highlighting its potential as a biocontrol agent.
Article
Agriculture, Multidisciplinary
Haining Xu, Chunhua Dai, Yingxiu Tang, Xueting Xu, Ekene Christopher Umego, Ronghai He, Haile Ma
Summary: The study utilized ARTP mutagenesis technology to successfully increase the production of Surfactin in Bacillus subtilis, resulting in the mutant strain M45 with higher growth rate and yield. The findings provide a basis for industrial production of Surfactin and shed light on the mutagenesis mechanism.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Medicine, Research & Experimental
Agnes Jakab, Fruzsina Kovacs, Noemi Balla, Zoltan Toth, Agota Ragyak, Zsofi Sajtos, Kinga Csillag, Csaba Nagy-Koteles, Daniel Nemes, Ildiko Bacskay, Istvan Pocsi, Laszlo Majoros, Akos T. Kovacs, Renato Kovacs
Summary: This study demonstrates that surfactin, a secondary metabolite derived from Bacillus subtilis, exhibits antifungal properties against Candida albicans. It inhibits the growth, adhesion, and morphogenesis of C. albicans, increases the level of reduced glutathione, and enhances the efficacy of fluconazole. Surfactin also affects the gene transcription of C. albicans, with down-regulation of genes involved in morphogenesis and metabolism, and up-regulation of genes associated with ribosome biogenesis, iron metabolism, and drug transport.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Parasitology
A. M. Manonmani, G. Prabakaran, S. L. Hoti
Article
Parasitology
G. Prabakaran, S. L. Hoti, A. M. Manonmani, K. Balaraman
Article
Parasitology
I. Geetha, A. M. Manonmani, G. Prabakaran
Article
Biotechnology & Applied Microbiology
I. Geetha, A. M. Manonmani
BIOLOGICAL CONTROL
(2008)
Article
Entomology
A. M. Manonmani, A. Mathivanan, R. Srinivasan, P. Jambulingam
JOURNAL OF MEDICAL ENTOMOLOGY
(2010)
Article
Biotechnology & Applied Microbiology
I. Geetha, A. M. Manonmani
LETTERS IN APPLIED MICROBIOLOGY
(2010)
Article
Agronomy
Irudayaraj Geetha, Kummankottil P. Paily, Arulsamy M. Manonmani
PEST MANAGEMENT SCIENCE
(2012)
Article
Public, Environmental & Occupational Health
Arulsamy Mary Manonmani, Ashok Kumar Mathivanan, Candassamy Sadanandane, Purushothaman Jambulingam
JOURNAL OF ARTHROPOD-BORNE DISEASES
(2013)
Article
Immunology
A. M. Manonmani, S. S. Sahu
INDIAN JOURNAL OF MEDICAL RESEARCH
(2008)
Article
Parasitology
A. M. Manonmani, C. Sadanandane, S. S. Sahu, A. Mathivanan, P. Jambulingam
Article
Biotechnology & Applied Microbiology
I. Geetha, G. Prabakaran, K. P. Paily, A. M. Manonmani, K. Balaraman
BIOLOGICAL CONTROL
(2007)
Article
Biotechnology & Applied Microbiology
G. Prabakaran, K. Balaraman, S. L. Hoti, A. M. Manonmani
BIOLOGICAL CONTROL
(2007)
Article
Parasitology
P Jambulingam, SS Sahu, A Manonmani
Article
Entomology
A Manonmani, N Nanda, P Jambulingam, S Sahu, T Vijayakumar, JR Vani, SK Subbarao
BULLETIN OF ENTOMOLOGICAL RESEARCH
(2003)