期刊
APPLIED BIOCHEMISTRY AND MICROBIOLOGY
卷 47, 期 6, 页码 580-585出版社
PLEIADES PUBLISHING INC
DOI: 10.1134/S0003683811060020
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资金
- Federal Special-Purpose Program Scientific and Scientific-Pedagogical Personnel of the Innovative Russia [14.740.11.0801]
Four major families of bacterial histone-like proteins (HU, IHF, H-NS, FIS), united on the basis of structural similarity and performing specific structural and regulatory functions in the cell, are discussed. Histone-like proteins perform topological modification of the chromosome (twisting, bending, and folding) and directly regulate the functioning of promoters of individual operons. Histone-like proteins are critical for the regulation of cell metabolism, are involved in the response to environmental changes, and play a key role in the transition to and maintenance of the resting cells of bacteria. DOI: 10.1134/S0003683811060020
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