Combretastatin A-4 derived imidazoles show cytotoxic, antivascular, and antimetastatic effects based on cytoskeletal reorganisation

Emerging molecular targets in melanoma invasion and metastasis

(2012) Jose L. Orgaz et al.   Pigment Cell & Melanoma Research

Cytotoxic and antivascular 1-methyl-4-(3-fluoro-4-methoxyphenyl)-5-(halophenyl)-imidazoles

(2011) Bernhard Biersack et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

(2011) James D. Orth et al.   MOLECULAR BIOLOGY OF THE CELL

Tumor angiogenesis: molecular pathways and therapeutic targets

(2011) Sara M Weis et al.   NATURE MEDICINE

Integrins in Cell Migration

(2011) A. Huttenlocher et al.   Cold Spring Harbor Perspectives in Biology

Novel compounds with antiangiogenic and antiproliferative potency for growth control of testicular germ cell tumours

(2010) B Nitzsche et al.   BRITISH JOURNAL OF CANCER

Oxazole-Bridged Combretastatin A Analogues with Improved Anticancer Properties

(2010) Bernhard Biersack et al.   ChemMedChem

Vascular effects dominate solid tumor response to treatment with combretastatin A-4-phosphate

(2010) Sarah Jane Lunt et al.   INTERNATIONAL JOURNAL OF CANCER

Microtubule depolymerizing vascular disrupting agents: novel therapeutic agents for oncology and other pathologies

(2010) Chryso Kanthou et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

4-(3-Halo/amino-4,5-dimethoxyphenyl)-5-aryloxazoles and -N-methylimidazoles That Are Cytotoxic against Combretastatin A Resistant Tumor Cells and Vascular Disrupting in a Cisplatin Resistant Germ Cell Tumor Model

(2010) Rainer Schobert et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mycotoxin Citrinin Induced Cell Cycle G2/M Arrest and Numerical Chromosomal Aberration Associated with Disruption of Microtubule Formation in Human Cells

(2010) Chia-Hao Chang et al.   TOXICOLOGICAL SCIENCES

Primary Endothelial Damage Is the Mechanism of Cardiotoxicity of Tubulin-Binding Drugs

(2010) Igor Mikaelian et al.   TOXICOLOGICAL SCIENCES

Metastasis mechanisms

(2009) Thomas R. Geiger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line

(2009) EVELYN ARANDA et al.   BIOLOGICAL RESEARCH

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

(2009) John M.L. Ebos et al.   CANCER CELL

Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

(2009) Marta Pàez-Ribes et al.   CANCER CELL

Antivascular Actions of Microtubule-Binding Drugs

(2009) E. L. Schwartz   CLINICAL CANCER RESEARCH

AVE8062: a new combretastatin derivative vascular disrupting agent

(2009) Angelo Delmonte et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Vascular Disrupting Activity of Tubulin-Binding 1,5-Diaryl-1H-imidazoles†

(2009) Katiuscia Bonezzi et al.   JOURNAL OF MEDICINAL CHEMISTRY