期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 78, 期 18, 页码 6773-6776出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.01650-12
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资金
- National Health and Medical Research Council
- Australian Research Council
Wolbachia pipientis delays RNA virus-induced mortality in Drosophila spp. We investigated whether Wolbachia-mediated protection was dependent on the small interfering RNA (siRNA) pathway, a key antiviral defense. Compared to Wolbachia-free flies, virus-induced mortality was delayed in Wolbachia-infected flies with loss-of-function of siRNA pathway components, indicating that Wolbachia-mediated protection functions in the absence of the canonical siRNA pathway.
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