期刊
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
卷 77, 期 1, 页码 369-373出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.01173-10
关键词
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资金
- Ministerio de Educacion y Ciencia (MEC) [AGL2006-01042]
- Ministerio de Ciencia e Innovacion (MICINN) [AGL2009-08348]
- Comunidad de Madrid (CAM), Spain [S-0505/AGR/0265, S2009/AGR-1489]
- CAM
Lactococcus garvieae DCC43 produces a bacteriocin, garvicin ML (GarML), with a molecular mass of 6,004.2 Da. Data from de novo amino acid sequencing by tandem mass spectrometry and nucleotide sequencing by reverse genetics suggested that the bacteriocin is synthesized as a 63-amino-acid precursor with a 3-amino-acid leader peptide that is removed by cleavage. Subsequently, a covalent linkage between the N and C termini forms the mature version of this novel 60-amino-acid circular bacteriocin.
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