Capsaicin induces apoptosis in human small cell lung cancer via the TRPV6 receptor and the calpain pathway

Transient Receptor Potential Ion Channels

(2013) Adrian T. Billeter et al.   ANNALS OF SURGERY

TRPV1 inhibition attenuates IL-13 mediated asthma features in mice by reducing airway epithelial injury

(2013) Rakhshinda Rehman et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Nicotine Induces the Up-regulation of the α7-Nicotinic Receptor (α7-nAChR) in Human Squamous Cell Lung Cancer Cells via the Sp1/GATA Protein Pathway

(2013) Kathleen C. Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vivo Detection of Human TRPV6-Rich Tumors with Anti-Cancer Peptides Derived from Soricidin

(2013) Chris V. Bowen et al.   PLoS One

Multidisciplinary Management of Small Cell Lung Cancer

(2013) Sarah B. Goldberg et al.   Surgical Oncology Clinics of North America

Plants vs. Cancer: A Review on Natural Phytochemicals in Preventing and Treating Cancers and Their Druggability

(2012) Hu Wang et al.   Anti-Cancer Agents in Medicinal Chemistry

Inhibition of Cholinergic Signaling Causes Apoptosis in Human Bronchioalveolar Carcinoma

(2012) J. K. Lau et al.   CANCER RESEARCH

The role of the TRPV6 channel in cancer

(2012) V’yacheslav Lehen’kyi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression

(2012) Jong Hun Lee et al.   PHARMACOLOGY & THERAPEUTICS

TRP Channels and Cancer: New Targets for Diagnosis and Chemotherapy

(2012) Giorgio Santoni et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

G Protein-coupled Receptor Signaling via Src Kinase Induces Endogenous Human Transient Receptor Potential Vanilloid Type 6 (TRPV6) Channel Activation

(2011) Jennifer Spehr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical and Pharmacological Aspects of Capsaicin

(2011) Maria Reyes-Escogido et al.   MOLECULES

Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy

(2011) Amteshwar Singh Jaggi et al.   TOXICOLOGY

Calpain and Caspase Orchestrated Death Signal to Accomplish Apoptosis Induced by Resveratrol and Its Novel Analog Hydroxstilbene-1 in Cancer Cells

(2010) P. Guha et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

1189 CAPSAICIN REDUCES PROLIFERATION AND INDUCES APOPTOSIS IN PROSTATE CANCER CELLS VIA TRPV6 MEDIATED PHENOMENON

(2010) Natalie Venier et al.   JOURNAL OF UROLOGY

Capsaicin Displays Anti-Proliferative Activity against Human Small Cell Lung Cancer in Cell Culture and Nude Mice Models via the E2F Pathway

(2010) Kathleen C. Brown et al.   PLoS One

Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner

(2009) C. Amantini et al.   CARCINOGENESIS

Capsaicin causes cell-cycle arrest and apoptosis in ER-positive and -negative breast cancer cells by modulating the EGFR/HER-2 pathway

(2009) N H Thoennissen et al.   ONCOGENE

Capsaicin-induced apoptosis is regulated by endoplasmic reticulum stress- and calpain-mediated mitochondrial cell death pathways

(2009) Mi-Ja Lee et al.   TOXICOLOGY

A Small Molecule Disruptor of Rb/Raf-1 Interaction Inhibits Cell Proliferation, Angiogenesis, and Growth of Human Tumor Xenografts in Nude Mice

(2008) R. Kinkade et al.   CANCER RESEARCH

Activated Cholinergic Signaling Provides a Target in Squamous Cell Lung Carcinoma

(2008) P. Song et al.   CANCER RESEARCH

Peripheral TRPV1 Receptors As Targets for Drug Development: New Molecules and Mechanisms

(2008) Arpad Szallasi et al.   CURRENT PHARMACEUTICAL DESIGN

The TRPV1 receptor is associated with preferential stress in large dorsal root ganglion neurons in early diabetic sensory neuropathy

(2008) Shuangsong Hong et al.   JOURNAL OF NEUROCHEMISTRY

Short-Chain Fatty Acids Induce Intestinal Transient Receptor Potential Vanilloid Type 6 Expression in Rats and Caco-2 Cells

(2008) Akiko Fukushima et al.   JOURNAL OF NUTRITION

Capsaicin induces apoptosis and terminal differentiation in human glioma A172 cells

(2008) Young-Gi Gil et al.   LIFE SCIENCES

The role of TRPV6 in breast carcinogenesis

(2008) K. A. Bolanz et al.   MOLECULAR CANCER THERAPEUTICS

Calciotropic and Magnesiotropic TRP Channels

(2008) Joost G. J. Hoenderop et al.   PHYSIOLOGY

Potential of Spice-Derived Phytochemicals for Cancer Prevention

(2008) Bharat Aggarwal et al.   PLANTA MEDICA

Stabilization of pulmonary mitochondrial enzyme system by capsaicin during benzo(a)pyrene induced experimental lung cancer

(2007) P. Anandakumar et al.   BIOMEDICINE & PHARMACOTHERAPY