TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis

Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions

(2011) Sarit Kahana et al.   CELLULAR SIGNALLING

Caspase signalling controls microglia activation and neurotoxicity

(2011) Miguel A. Burguillos et al.   NATURE

Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy

(2011) Qian Huang et al.   NATURE MEDICINE

Membrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization

(2010) Sylvie Montessuit et al.   CELL

Mutant PIK3CA licenses TRAIL and CD95L to induce non-apoptotic caspase-8-mediated ROCK activation

(2010) M Ehrenschwender et al.   CELL DEATH AND DIFFERENTIATION

Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level

(2010) A Morizot et al.   CELL DEATH AND DIFFERENTIATION

Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis

(2010) M Hörnle et al.   ONCOGENE

New insights into apoptosis signaling by Apo2L/TRAIL

(2010) F Gonzalvez et al.   ONCOGENE

Proteasome inhibitor sensitizes oral squamous cell carcinoma cells to TRAIL-mediated apoptosis

(2010) Yoshiba   ONCOLOGY REPORTS

Caspase-3 Is Transiently Activated without Cell Death during Early Antigen Driven Expansion of CD8+ T Cells In Vivo

(2010) Scott McComb et al.   PLoS One

c-Cbl-mediated degradation of TRAIL receptors is responsible for the development of the early phase of TRAIL resistance

(2009) Jae J. Song et al.   CELLULAR SIGNALLING

TRAIL induces proliferation of human glioma cells by c-FLIPL-mediated activation of ERK1/2

(2008) U. Vilimanovich et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Caspase‐3 enhances lung metastasis and cell migration in a protease‐independent mechanism through the ERK pathway

(2008) Yu‐Jung Cheng et al.   INTERNATIONAL JOURNAL OF CANCER

Cell motility through plasma membrane blebbing

(2008) Oliver T. Fackler et al.   JOURNAL OF CELL BIOLOGY

Blebs lead the way: how to migrate without lamellipodia

(2008) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY