Article
Biochemistry & Molecular Biology
Mackenzie R. Lovegrove, Peter K. Dearden, Elizabeth J. Duncan
Summary: Eusocial insect societies are characterized by reproductive division of labour maintained by reproductive dominants or queens. Queen mandibular pheromone (QMP), produced by queen honeybees, can inhibit worker reproduction and also has effects on non-target arthropods. In Drosophila melanogaster, QMP treatment mimics the starvation response, leading to reduced reproduction and changes in ovary function. These findings suggest that QMP evolved by co-opting nutrition signalling pathways to regulate reproduction.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2023)
Article
Multidisciplinary Sciences
Meng Jie Jin, Zi Long Wang, Zi Hao Wu, Xu Jiang He, Yong Zhang, Qiang Huang, Li Zhen Zhang, Xiao Bo Wu, Wei Yu Yan, Zhi Jiang Zeng
Summary: Phenotypic dimorphism between honeybee queens and workers is regulated by chromosomal conformation and H3K27ac and H3K4me1 modifications, as revealed by Hi-C and ChIP-Seq technologies. Queens have more chromosome interactions and unique H3K27ac modifications, while workers have more H3K4me1 modifications. The potential caste gene Map3k15 is identified in queen-worker differentiation.
Article
Environmental Sciences
Maxime Pineaux, Stephane Grateau, Tiffany Lirand, Pierrick Aupinel, Freddie -Jeanne Richard
Summary: The widely used fungicide boscalid has detrimental effects on honey bee queen reproduction, leading to increased mortality and reduced sperm storage. However, it does not affect paternity frequency in successfully established colonies.
ENVIRONMENTAL POLLUTION
(2023)
Article
Engineering, Electrical & Electronic
Jun-Fei Zhang, Fan Wu, Ming-Zhu Tang, Dong-Xiao Chen, Jing Tan, Qing-Jun Liu, Hong-Liang Li
Summary: A biosensor specific for queen pheromone components was successfully constructed in this study, showing high sensitivity and specificity. The biosensor demonstrated a wide detection linear range and excellent detection capability for methyl p-hydroxy-benzoate (HOB) and vanillyl alcohol (HVA), with theoretical detection limits as low as 10(-8) mol/L. This biosensor is beneficial for the future protection and sustainability of honeybee resources.
IEEE SENSORS JOURNAL
(2021)
Article
Microbiology
Jiandong Yang, Yun Zhong, Liqun Xu, Bo Zeng, Kang Lai, Mingxian Yang, Diyan Li, Ye Zhao, Mingwang Zhang, Debing Li
Summary: The study found that the gut microbiota of asexual hybridization queens bred through nutritional crossbreeding differs slightly from normally bred queens, with dominant genera being Brevundimonas, Bombella, and Lactobacillus, and more related to A. mellifera queens. Genetic background plays a more dominant role in shaping the gut microbiota of honeybee queens.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Sonia E. Eynard, Alain Vignal, Benjamin Basso, Kamila Canale-Tabet, Yves Le Conte, Axel Decourtye, Lucie Genestout, Emmanuelle Labarthe, Fanny Mondet, Bertrand Servin
Summary: This study introduces new statistical methods to accurately estimate the genetic ancestry and reconstruct the genotypes of the queen from pool sequencing data of workers in a eusocial colony, allowing for genetic diversity monitoring, genomic-based studies, and selective breeding.
MOLECULAR ECOLOGY RESOURCES
(2022)
Review
Agriculture, Multidisciplinary
Cassandra Uthoff, Masun Nabhan Homsi, Martin von Bergen
Summary: Honeybees use various signals to communicate. Acoustic and vibration recordings are being used to automatically monitor colony behavior and health. Queen presence and swarming preparation are important indicators for assessing colony state, but there are challenges in using these recordings to detect them. This review provides an overview of studies using acoustic and vibration recordings to determine queen presence and indicators of swarming, discussing methods, challenges, and future improvements.
COMPUTERS AND ELECTRONICS IN AGRICULTURE
(2023)
Article
Toxicology
Michael P. Kellett, Jordan T. Jatko, Caitlin L. Darling, Scott W. Ventrello, Lisa J. Bain
Summary: This study found that arsenic exposure impairs intestinal stromal cells, particularly trophocytes and telocytes, leading to alterations in the Bmp signaling pathway. However, differentiated epithelial cells were not affected.
TOXICOLOGY LETTERS
(2022)
Article
Behavioral Sciences
Cintia Akemi Oi
Summary: The queen mandibular pheromone (QMP) plays a crucial role in honeybees, but its effects on other insect species are still unclear.
JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY
(2022)
Article
Entomology
Tetsu Yamamoto, Michio Sugahara, Ryuichi Okada, Hidetoshi Ikeno
Summary: The study revealed that the piping signals of two honeybee species, Apis cerana and Apis mellifera, had different temporal structures. The tooting of A. cerana consisted of almost one long syllable, while that of A. mellifera was constructed from several syllables. The quacking of both species comprised around 50 short syllables, but the duration and period of the syllables of A. cerana were about half those of A. mellifera.
Article
Endocrinology & Metabolism
Mengyu Liu, Wenzhu Li, Xiaowei Zhou, Mingjuan Zhou, Wenjie Zhang, Qiang Liu, Aijun Zhang, Bufang Xu
Summary: This study found that cell-free fat extract (CEFFE) can rescue the decline in ovarian function and improve fertility in naturally aging mice. CEFFE was found to increase sex hormone levels, angiogenesis, and the number of growth follicles. It also improved granulosa cell function by promoting proliferation, alleviating senescence, and repairing DNA damage.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Ecology
Ian M. Traniello, Syed Abbas Bukhari, Payam Dibaeinia, Guillermo Serrano, Arian Avalos, Amy Cash Ahmed, Alison L. Sankey, Mikel Hernaez, Saurabh Sinha, Sihai Dave Zhao, Julian Catchen, Gene E. Robinson
Summary: Understanding the genetic basis of collective behavior in honeybees, researchers found that genetic variation for colony aggression influences individual differences in brain gene expression and regulation. Differences in gene regulatory network architecture were found between aggressive soldiers and non-aggressive foragers.
NATURE ECOLOGY & EVOLUTION
(2023)
Article
Biochemistry & Molecular Biology
Andrew Ndhlovu, Pierre M. Durand, Grant Ramsey
Summary: Programmed cell death (PCD) in unicellular organisms can be seen as an altruistic trait, possibly explained by kin selection or group selection theory. The Black Queen Hypothesis (BQH) suggests that PCD functions as a black queen in microbial communities, with leakiness and costliness being key characteristics. More empirical data is needed to fully assess this hypothesis, but it provides a useful framework for studying the role of PCD in communities.
Article
Entomology
Cole Baril, Christophe M. R. LeMoine, Bryan J. Cassone
Summary: In this study, the novel black queen cell virus (BQCV) was identified in mosquitoes collected from Manitoba, Canada. The nearly complete genome sequence of BQCV was obtained, revealing its high similarity to a BQCV isolate from Sweden. It is hypothesized that mosquitoes acquired the virus indirectly through foraging at the same nectar sources as honeybees.
JOURNAL OF INSECT SCIENCE
(2023)
Article
Food Science & Technology
Akang Dan, Yushi Chen, Yongqi Tian, Shaoyun Wang
Summary: The study aimed to explore the potential of the fungus Paecilomyces hepiali as a foodborne antioxidant and anti-aging agent. The n-butanol extract from rice cultures showed significant antioxidant activity and prolonged the lifespan of Drosophila on a high-fat diet. Further research revealed the presence of dimerumic acid as the major antioxidant compound in PHE.
FOOD SCIENCE AND HUMAN WELLNESS
(2023)
Article
Medicine, Research & Experimental
Soonho Kwon, Yu Shan Hsieh, You Kyoung Shin, Purum Kang, Geun Hee Seol
BIOMEDICINE & PHARMACOTHERAPY
(2018)
Article
Physiology
You Kyoung Shin, Yu Shan Hsieh, Soonho Kwon, Hui Su Lee, Geun Hee Seol
JOURNAL OF APPLIED PHYSIOLOGY
(2018)
Article
Medicine, Research & Experimental
Yu Shan Hsieh, You Kyoung Shin, A. Young Han, Soonho Kwon, Geun Hee Seol
Article
Chemistry, Medicinal
You Kyoung Shin, Yu Shan Hsieh, A. Young Han, Kwang-Won Lee, Geun Hee Seol
PHYTOTHERAPY RESEARCH
(2020)
Article
Medicine, Research & Experimental
You Kyoung Shin, Yu Shan Hsieh, A. Young Han, Soonho Kwon, Geun Hee Seol
EXPERIMENTAL BIOLOGY AND MEDICINE
(2020)
Article
Pharmacology & Pharmacy
Eunhye Seo, You Kyoung Shin, Yu Shan Hsieh, Jeong-Min Lee, Geun Hee Seol
Summary: Chronic nicotine exposure exacerbates symptoms in rats with rheumatoid arthritis, including muscle wasting. Research indicates that lavender oil and LA can prevent this muscle wasting condition.
JOURNAL OF PHARMACOLOGICAL SCIENCES
(2021)
Article
Medicine, General & Internal
Yan-Yu Lin, Shuen-Fu Weng, Chung-Huei Hsu, Chen-Ling Huang, Yu-Pei Lin, Min-Chun Yeh, A-Young Han, Yu-Shan Hsieh
Summary: This study compared the effects of metformin-based dual therapy and triple therapy on glycemic control and lipid profile changes in Taiwanese patients with T2DM. The results showed that the combination of metformin and DPP4 and SGLT2 inhibitor therapy was more effective in reducing LDL-C and improving total cholesterol and HDL-C compared to metformin monotherapy. Dual therapy of metformin and linagliptin had a better glycemic control ability than metformin monotherapy, while triple therapy of empagliflozin and linagliptin had a better glycemic control ability than linagliptin dual therapy. Additionally, triple therapy of dapagliflozin and saxagliptin had a better lipid control ability than dapagliflozin dual therapy.
FRONTIERS IN MEDICINE
(2022)
Article
Endocrinology & Metabolism
Yu-Shan Hsieh, Min-Chun Yeh, Yan-Yu Lin, Shuen-Fu Weng, Chung-Huei Hsu, Chen-Ling Huang, Yu-Pei Lin, A-Young Han
Summary: This study identifies the significance of serum lactate dehydrogenase (LDH) level in T2DM patients and investigates its relationship with other variables.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Yan-Yu Lin, Yu-Shan Hsieh
Summary: In this study, the relationship between iodine nutritional status and the prevalence of BRAF600E mutation in PTC patients was analyzed. The results showed that iodine intake did not significantly influence the prevalence of BRAFV600E mutation. This study provides preliminary research on the association between dietary iodine intake and BRAFV600E mutation in PTC patients.
ARCHIVES OF ENDOCRINOLOGY METABOLISM
(2023)
Article
Medicine, General & Internal
Yi-Wei Lee, Ting-Teng Yang, Yan-Yu Lin, Yu-Shan Hsieh
Summary: This study aimed to explore the relationship between elevated thyroid hormone levels and lipid profile in insulin resistance in patients with type 2 diabetes mellitus (T2DM) with hyperthyroidism. The results showed that elevated thyroid hormone levels were positively correlated with insulin resistance and triglyceride levels. Additionally, decreased high-density lipoprotein levels were associated with insulin resistance. In conclusion, elevated thyroid hormone levels due to hyperthyroidism may alter the lipid profile and insulin resistance in patients with T2DM.
Review
Medicine, General & Internal
Yu-Shan Hsieh
Summary: Graves' disease can complicate glucose control in patients with type 2 diabetes mellitus. Selecting a drug with limited blood glucose side effects is important in these patients. This review examines the effects of current antithyroid drugs used for Graves' disease on blood glucose control in patients with type 2 diabetes mellitus.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Medicine, General & Internal
Yi-Wei Lee, Yan-Yu Lin, Shuen-Fu Weng, Chung-Huei Hsu, Chen-Ling Huang, Yu-Pei Lin, Yu-Shan Hsieh
Summary: This study found that diabetes affects liver function in patients with Graves disease. The presence of diabetes worsens thyroid function control. The correlation between glutamate pyruvate transaminase (GPT) and triiodothyronine was observed in diabetes patients but not with free thyroxine (FT4).
Article
Medicine, General & Internal
Yan-Yu Lin, Yu-Shan Hsieh
Summary: A 41-year-old male patient presented with acute lower limb weakness, severe hypokalemia, and hyperthyroidism. Chronic alcohol abuse may have increased the patient's tolerance to the profound hypokalemia, delaying the manifestation of critical symptoms.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Physiology
Yu Shan Hsieh, You Kyoung Shin, Geun Hee Seol
Summary: The study found that linalyl acetate (LA) has a protective effect on neural cells, astrocytes, and microglia damaged under conditions simulating CRII, reducing LDH release. The protective effects of LA on different NVU cell types may vary, involving mechanisms such as blocking oxidative stress and reducing nitric oxide abnormalities.
CHINESE JOURNAL OF PHYSIOLOGY
(2021)
Article
Medicine, Research & Experimental
You Kyoung Shin, Yu Shan Hsieh, A. Young Han, Soonho Kwon, Purum Kang, Geun Hee Seol